TGS1 Protein (AA 713-853, partial) (His-SUMO Tag)
-
- 抗原 See all TGS1 蛋白
- TGS1 (Trimethylguanosine Synthase 1 (TGS1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 713-853, partial
-
宿主
- 人
-
资源
- 大肠杆菌(E. Coli)
- 标记
- This TGS1 protein is labelled with His-SUMO Tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- MRVIAIDIDP VKIALARNNA EVYGIADKIE FICGDFLLLA SFLKADVVFL SPPWGGPDYA TAETFDIRTM MSPDGFEIFR LSKKITNNIV YFLPRNADID QVASLAGPGG QVEIEQNFLN NKLKTITAYF GDLIRRPASE T
- 纯化方法
- SDS-PAGE
- 纯度
- > 90 %
- Top Product
- Discover our top product TGS1 蛋白
-
-
- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 0.1-2 mg/mL
- 缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
- 储存条件
- -80 °C,4 °C,-20 °C
- 储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
-
- 抗原
- TGS1 (Trimethylguanosine Synthase 1 (TGS1))
- 别名
- TGS1 (TGS1 产品)
- 别名
- NCOA6IP Protein, PIMT Protein, PIPMT Protein, D4Ertd800e Protein, Ncoa6ip Protein, Pimt Protein, trimethylguanosine synthase 1 Protein, trimethylguanosine synthase 1 L homeolog Protein, TGS1 Protein, Tgs1 Protein, tgs1.L Protein
- 背景
- Catalyzes the 2 serial methylation steps for the conversion of the 7-monomethylguanosine (m7G) caps of snRNAs and snoRNAs to a 2,2,7-trimethylguanosine (m(2,2,7)G) cap structure. The enzyme is specific for guanine, and N7 methylation must precede N2 methylation. Hypermethylation of the m7G cap of U snRNAs leads to their concentration in nuclear foci, their colocalization with coilin and the formation of canonical Cajal bodies (CBs). Plays a role in transcriptional regulation.
- 分子量
- 31.64 kDa
- UniProt
- Q96RS0
- 途径
- Mitotic G1-G1/S Phases, Regulation of Lipid Metabolism by PPARalpha, Ribonucleoprotein Complex Subunit Organization
-