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TGS1 Protein (AA 713-853, partial) (His-SUMO Tag)

TGS1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % SDS
产品编号 ABIN5711660
发货至: 中国
  • 抗原 See all TGS1 蛋白
    TGS1 (Trimethylguanosine Synthase 1 (TGS1))
    蛋白类型
    Recombinant
    产品特性
    AA 713-853, partial
    宿主
    • 3
    • 1
    • 1
    资源
    • 2
    • 2
    • 1
    大肠杆菌(E. Coli)
    标记
    This TGS1 protein is labelled with His-SUMO Tag.
    应用范围
    SDS-PAGE (SDS)
    序列
    MRVIAIDIDP VKIALARNNA EVYGIADKIE FICGDFLLLA SFLKADVVFL SPPWGGPDYA TAETFDIRTM MSPDGFEIFR LSKKITNNIV YFLPRNADID QVASLAGPGG QVEIEQNFLN NKLKTITAYF GDLIRRPASE T
    纯化方法
    SDS-PAGE
    纯度
    > 90 %
    Top Product
    Discover our top product TGS1 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.1-2 mg/mL
    缓冲液
    20 mM Tris-HCl based buffer, pH 8.0
    储存条件
    -80 °C,4 °C,-20 °C
    储存方法
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • 抗原
    TGS1 (Trimethylguanosine Synthase 1 (TGS1))
    别名
    TGS1 (TGS1 产品)
    别名
    NCOA6IP Protein, PIMT Protein, PIPMT Protein, D4Ertd800e Protein, Ncoa6ip Protein, Pimt Protein, trimethylguanosine synthase 1 Protein, trimethylguanosine synthase 1 L homeolog Protein, TGS1 Protein, Tgs1 Protein, tgs1.L Protein
    背景
    Catalyzes the 2 serial methylation steps for the conversion of the 7-monomethylguanosine (m7G) caps of snRNAs and snoRNAs to a 2,2,7-trimethylguanosine (m(2,2,7)G) cap structure. The enzyme is specific for guanine, and N7 methylation must precede N2 methylation. Hypermethylation of the m7G cap of U snRNAs leads to their concentration in nuclear foci, their colocalization with coilin and the formation of canonical Cajal bodies (CBs). Plays a role in transcriptional regulation.
    分子量
    31.64 kDa
    UniProt
    Q96RS0
    途径
    Mitotic G1-G1/S Phases, Regulation of Lipid Metabolism by PPARalpha, Ribonucleoprotein Complex Subunit Organization
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