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TFEB 抗体

(Transcription Factor EB (TFEB))
Transcription factor that specifically recognizes and binds E-box sequences (3'-CANNTG-5'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFE3 or MITF. In association with TFE3, activates the expression of CD40L in T-cells, thereby playing a role in T- cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes and binds the CLEAR-box sequence (5'-GTCACGTGAC-3') present in the regulatory region of many lysosomal genes, leading to activate their expression. It thereby plays a central role in expression of lysosomal genes. Specifically recognizes the gamma-E3 box, a subset of E-boxes, present in the heavy-chain immunoglobulin enhancer. Plays a role in the signal transduction processes required for normal vascularization of the placenta.
TFEB 抗体  (AA 1-476) TFEB 抗体  (AA 1-476) TFEB 抗体 (AA 1-476) (ABIN563503)

TFEB 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal S1 unconjugated

TFEB 抗体  (N-Term) TFEB 抗体  (N-Term) TFEB 抗体 (N-Term) (ABIN184741)

Verified TFEB 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated

TFEB 抗体  (Middle Region) TFEB 抗体  (Middle Region) TFEB 抗体 (Middle Region) (ABIN2787554)

TFEB 适用: 人, 犬, Cow, 马, 山羊, 兔 WB 宿主: 兔 Polyclonal unconjugated

TFEB 抗体 by Grade

Find TFEB 抗体 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

TFEB 抗体 by 适用

Find TFEB 抗体 for a variety of species such as anti-Human TFEB, anti-Mouse TFEB, anti-Rat TFEB. The species listed below are among those available. Click on a link to go to the corresponding products.

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TFEB 抗体 by 抗原表位

Find TFEB 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

TFEB 抗体 by 克隆形成能力

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TFEB 抗体 by 克隆

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TFEB 抗体 by 标记

Find TFEB 抗体 with a specific conjugate such as FITC, Biotin, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular TFEB 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (1)
  • (5)
Cat. No. ABIN563503
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (8)
Cat. No. ABIN184741
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow, Dog, Goat, Horse, Human, Rabbit
Application WB
Validations
  • (5)
Cat. No. ABIN2787554
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7172536
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF
Validations
  • (3)
Cat. No. ABIN7263315
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7172534
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN3187234
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC (p), EIA
Validations
  • (3)
Cat. No. ABIN1450147
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro)
Validations
  • (1)
Cat. No. ABIN755392
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN563502
Quantity 50 μL
Datasheet Datasheet

Application WB
Validations
  • (1)
Cat. No. ABIN202620
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Goat, Horse, Human, Monkey, Rabbit
Application WB
Validations
  • (1)
Cat. No. ABIN6745235
Quantity 100 μL
Datasheet Datasheet
Reactivity Bat, Cow, Goat, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN6736030
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN791477
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN1533649
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our TFEB 抗体

Ye, Wang, Hu, Shen, Fan, Chen, Ma, Wu, Xiang: "Restoring autophagic flux attenuates cochlear spiral ganglion neuron degeneration by promoting TFEB nuclear translocation via inhibiting MTOR." in: Autophagy, Vol. 15, Issue 6, pp. 998-1016, (2019) (PubMed).

Bhatelia, Singh, Prajapati, Sripada, Roy, Singh: "MITA modulated autophagy flux promotes cell death in breast cancer cells." in: Cellular signalling, Vol. 35, pp. 73-83, (2018) (PubMed).

Awad, Panicker, Deranieh, Srikanth, Brown, Voit, Peesay, Park, Zambidis, Feldman: "Altered Differentiation Potential of Gaucher's Disease iPSC Neuronal Progenitors due to Wnt/β-Catenin Downregulation." in: Stem cell reports, Vol. 9, Issue 6, pp. 1853-1867, (2017) (PubMed).

Luo, Ma, Yang, Wang, Zhang, Zhang, Liu, Liu: "TFEB regulates PER3 expression via glucose-dependent effects on CLOCK/BMAL1." in: The international journal of biochemistry & cell biology, Vol. 78, pp. 31-42, (2017) (PubMed).

Nakamura, Karalay, Jäger, Horikawa, Klein, Nakamura, Latza, Templer, Dieterich, Antebi: "Mondo complexes regulate TFEB via TOR inhibition to promote longevity in response to gonadal signals." in: Nature communications, Vol. 7, pp. 10944, (2016) (PubMed).

Ju, Yan, Liu, Li, Sheng, Zhang, Li, Liang, Huang, Liu, Zhao, Zhang, Zou, Du, Zhong, Zhou, Yang, Lu, Tian, Li, Zhang, Jin, Jiang: "Neuraminidase of Influenza A Virus Binds Lysosome-Associated Membrane Proteins Directly and Induces Lysosome Rupture." in: Journal of virology, Vol. 89, Issue 20, pp. 10347-58, (2015) (PubMed).

Kawano, Ito, Kanai, Nakamura, Tada, Takai, Horie, Kobayashi, Hino: "Aberrant differentiation of Tsc2-deficient teratomas associated with activation of the mTORC1-TFE3 pathway." in: Oncology reports, Vol. 34, Issue 5, pp. 2251-8, (2015) (PubMed).

Hubbi, Hu, Kshitiz, Ahmed, Levchenko, Semenza: "Chaperone-mediated autophagy targets hypoxia-inducible factor-1α (HIF-1α) for lysosomal degradation." in: The Journal of biological chemistry, Vol. 288, Issue 15, pp. 10703-14, (2013) (PubMed).

Roczniak-Ferguson, Petit, Froehlich, Qian, Ky, Angarola, Walther, Ferguson: "The transcription factor TFEB links mTORC1 signaling to transcriptional control of lysosome homeostasis." in: Science signaling, Vol. 5, Issue 228, pp. ra42, (2012) (PubMed).

Esumi, Kachi, Campochiaro, Zack: "VMD2 promoter requires two proximal E-box sites for its activity in vivo and is regulated by the MITF-TFE family." in: The Journal of biological chemistry, Vol. 282, Issue 3, pp. 1838-50, (2007) (PubMed).

Aliases for TFEB 抗体

transcription factor EB (TFEB) 抗体
transcription factor EB (tfeb) 抗体
transcription factor EB (Tfeb) 抗体
alphatfeb 抗体
ALPHATFEB 抗体
BHLHE35 抗体
bHLHe35 抗体
MGC145796 抗体
tcfeb 抗体
TCFEB 抗体
Tcfeb 抗体
TFEB 抗体
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