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TDG 抗体

(Thymine-DNA Glycosylase (TDG))
The protein encoded by this gene belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. This gene may have a pseudogene in the p arm of chromosome 12. [provided by RefSeq, Jul 2008].
TDG 抗体  (AA 141-410) TDG 抗体  (AA 141-410) TDG 抗体 (AA 141-410) (ABIN7153379)

TDG 适用: 人 ELISA, IHC, WB 宿主: 兔 Polyclonal unconjugated

TDG 抗体  (Internal Region) TDG 抗体  (Internal Region) TDG 抗体 (Internal Region) (ABIN6258811)

TDG 适用: 人, 小鼠, 大鼠 ELISA, ICC, IF, WB 宿主: 兔 Polyclonal unconjugated

TDG 抗体  (Center) TDG 抗体  (Center) TDG 抗体 (Center) (ABIN7299484)

TDG 适用: 人, 小鼠, 大鼠, Cow IC, IF, WB 宿主: 兔 Polyclonal unconjugated

TDG 抗体 by 适用

Find TDG 抗体 for a variety of species such as anti-Human TDG, anti-Mouse TDG, anti-Rat TDG. The species listed below are among those available. Click on a link to go to the corresponding products.

TDG 抗体 by 应用范围

Find TDG 抗体 validated for a specific application such as WB, ELISA, IF, IHC. Some of the available applications are listed below. Click on a link to go to the corresponding products.

TDG 抗体 by 抗体来源

Find TDG 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

TDG 抗体 by 抗原表位

Find TDG 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

TDG 抗体 by 克隆形成能力

Find available monoclonal or polyclonal TDG 抗体. Click on a link to go to the corresponding products.

TDG 抗体 by 克隆

Find TDG 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

TDG 抗体 by 标记

Find TDG 抗体 with a specific conjugate such as Alexa Fluor 488, Alexa Fluor 555, Alexa Fluor 594. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular TDG 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC, WB
Validations
  • (3)
Cat. No. ABIN7153379
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, ICC, IF, WB
Validations
  • (2)
Cat. No. ABIN6258811
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Human, Mouse, Rat
Application IC, IF, WB
Validations
  • (2)
Cat. No. ABIN7299484
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application FACS, ELISA, WB
Validations
  • (2)
Cat. No. ABIN2504505
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application FACS, ELISA, WB
Validations
  • (2)
Cat. No. ABIN2504506
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application IF, WB
Validations
  • (2)
Cat. No. ABIN520808
Quantity 50 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC
Validations
  • (4)
Cat. No. ABIN967162
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Mouse
Application WB
Validations
  • (1)
Cat. No. ABIN6972851
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN7256254
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IF
Validations
  • (1)
Cat. No. ABIN7256880
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, WB
Validations
  • (1)
Cat. No. ABIN1533874
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN520809
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application EIA, WB
Validations
  • (1)
Cat. No. ABIN453411
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human, Mouse
Application EIA, WB
Validations
  • (1)
Cat. No. ABIN453412
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application ELISA, IF, IHC, WB
Validations
Cat. No. ABIN7188253
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our TDG 抗体

Galanos, Pappas, Polyzos, Kotsinas, Svolaki, Giakoumakis, Glytsou, Pateras, Swain, Souliotis, Georgakilas, Geacintov, Scorrano, Lukas, Lukas, Livneh, Lygerou, Chowdhury, Sørensen, Bartek, Gorgoulis: "Mutational signatures reveal the role of RAD52 in p53-independent p21-driven genomic instability." in: Genome biology, Vol. 19, Issue 1, pp. 37, (2018) (PubMed).

Lin, Kang, Lu, Wang, Ma, Leung: "A G-quadruplex-selective luminescent probe with an anchor tail for the switch-on detection of thymine DNA glycosylase activity." in: Biosensors & bioelectronics, Vol. 86, pp. 849-57, (2016) (PubMed).

Huang, Lu, Ding, Chu, Hsu, Chen, Tsao, Chen, Lee, Shan, Chen: "TGFβ promotes mesenchymal phenotype of pancreatic cancer cells, in part, through epigenetic activation of VAV1." in: Oncogene, Vol. 36, Issue 16, pp. 2202-2214, (2016) (PubMed).

Baba, Maita, Jee, Uchimura, Saitoh, Sugasawa, Hanaoka, Tochio, Hiroaki, Shirakawa: "Crystal structure of thymine DNA glycosylase conjugated to SUMO-1." in: Nature, Vol. 435, Issue 7044, pp. 979-82, (2005) (PubMed).

Hardeland, Steinacher, Jiricny, Schär: "Modification of the human thymine-DNA glycosylase by ubiquitin-like proteins facilitates enzymatic turnover." in: The EMBO journal, Vol. 21, Issue 6, pp. 1456-64, (2002) (PubMed).

Neddermann, Gallinari, Lettieri, Schmid, Truong, Hsuan, Wiebauer, Jiricny: "Cloning and expression of human G/T mismatch-specific thymine-DNA glycosylase." in: The Journal of biological chemistry, Vol. 271, Issue 22, pp. 12767-74, (1996) (PubMed).

Neddermann, Jiricny: "Efficient removal of uracil from G.U mispairs by the mismatch-specific thymine DNA glycosylase from HeLa cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 91, Issue 5, pp. 1642-6, (1994) (PubMed).

Aliases for TDG 抗体

thymine DNA glycosylase (TDG) 抗体
thymine DNA glycosylase, tandem duplicate 1 (tdg.1) 抗体
putative g/t mismatch-specific thymine DNA glycosylase (Smp_149220) 抗体
G/T mismatch-specific thymine DNA glycosylase (Tsp_05734) 抗体
thymine DNA glycosylase S homeolog (tdg.S) 抗体
thymine DNA glycosylase (tdg) 抗体
thymine DNA glycosylase (Tdg) 抗体
thymine-DNA glycosylase (Tdg) 抗体
5-MCDG 抗体
E130317C12Rik 抗体
hTDG 抗体
JZA-3 抗体
Jza1 抗体
MGC82456 抗体
MGC89441 抗体
wu:fb44b11 抗体
zgc:110622 抗体
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