TDG 抗体
(Thymine-DNA Glycosylase (TDG))
The protein encoded by this gene belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. This gene may have a pseudogene in the p arm of chromosome 12. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| TDG 抗体 (AA 141-410) | 人 | 兔 Polyclonal |
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| TDG 抗体 (AA 360-410) | 人 | 兔 Polyclonal |
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| TDG 抗体 (N-Term) | 人, 小鼠 | 兔 Polyclonal |
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| TDG 抗体 (C-Term) | 人 | 兔 Polyclonal |
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| TDG 抗体 (AA 1-410) | 人 | 小鼠 Polyclonal |
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| TDG 抗体 | 小鼠 | 兔 Polyclonal |
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| TDG 抗体 (C-Term) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| TDG 抗体 (AA 1-160) | 人 | 兔 Polyclonal |
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| TDG 抗体 (AA 1-410) | 人 | 小鼠 Monoclonal |
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| TDG 抗体 (Internal Region) | 人, 小鼠 | 小鼠 Monoclonal |
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| TDG 抗体 (AA 1-410) | 人 | 兔 Polyclonal |
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| TDG 抗体 (AA 15-370) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| TDG 抗体 (AA 115-343) | 人 | 兔 Polyclonal |
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| TDG 抗体 (ubLys330) | 人, 小鼠, 大鼠 | Polyclonal |
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| TDG 抗体 (AA 1-80) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| TDG 抗体 (AA 81-110) | 人, 小鼠 | 兔 Polyclonal |
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| TDG 抗体 (AA 281-310) | 人 | 兔 Polyclonal |
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| TDG 抗体 (AA 360-410) | 人, 猴 | 兔 Polyclonal |
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| TDG 抗体 (Internal Region) | 人, 小鼠, 大鼠, Cow | 兔 Polyclonal |
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| TDG 抗体 | 人 | 小鼠 Monoclonal |
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Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 141-410
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- IP (Immunoprecipitation: 所列应用)
- IHC (fp) (Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 360-410
Primary Antibody
- WB (Western Blotting: 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 克隆
- RB19893
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- AA 81-110, N-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 克隆
- RB19894
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- AA 281-310, C-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 1-410
Primary Antibody
- IHC (Immunohistochemistry: 所列应用)
4 references - 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- C-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 1-160
Primary Antibody
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- IF (Immunofluorescence: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- AT2F7
- 标记
- unconjugated
- 抗体亚型
- IgG1 kappa
- 抗原表位
- AA 1-410
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人, 小鼠
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- AFfirm8968
- 标记
- unconjugated
- 抗体亚型
- IgG1
- 抗原表位
- Internal Region
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 1-410
Primary Antibody
- WB (Western Blotting: 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- ELISA (ELISA: 所列应用)
- IF (Immunofluorescence: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 15-370
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 115-343
Primary Antibody
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- ubLys330
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- IF (Immunofluorescence: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 1-80
Primary Antibody
- WB (Western Blotting: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 81-110
Primary Antibody
- WB (Western Blotting: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 281-310
Primary Antibody
- WB (Western Blotting: 所列应用)
- IP (Immunoprecipitation: 所列应用)
- 适用
- 人, 猴
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 360-410
Primary Antibody
- WB (Western Blotting: 所列应用)
- IF (Immunofluorescence: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠, Cow
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- Internal Region
Latest Publications for our TDG 抗体
: "Mutational signatures reveal the role of RAD52 in p53-independent p21-driven genomic instability." in: Genome biology, Vol. 19, Issue 1, pp. 37, (2018) (PubMed).
: "A G-quadruplex-selective luminescent probe with an anchor tail for the switch-on detection of thymine DNA glycosylase activity." in: Biosensors & bioelectronics, Vol. 86, pp. 849-57, (2016) (PubMed).
: "TGFβ promotes mesenchymal phenotype of pancreatic cancer cells, in part, through epigenetic activation of VAV1." in: Oncogene, Vol. 36, Issue 16, pp. 2202-2214, (2016) (PubMed).
: "Crystal structure of thymine DNA glycosylase conjugated to SUMO-1." in: Nature, Vol. 435, Issue 7044, pp. 979-82, (2005) (PubMed).
: "Modification of the human thymine-DNA glycosylase by ubiquitin-like proteins facilitates enzymatic turnover." in: The EMBO journal, Vol. 21, Issue 6, pp. 1456-64, (2002) (PubMed).
: "Cloning and expression of human G/T mismatch-specific thymine-DNA glycosylase." in: The Journal of biological chemistry, Vol. 271, Issue 22, pp. 12767-74, (1996) (PubMed).
: "Efficient removal of uracil from G.U mispairs by the mismatch-specific thymine DNA glycosylase from HeLa cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 91, Issue 5, pp. 1642-6, (1994) (PubMed).
: "A G-quadruplex-selective luminescent probe with an anchor tail for the switch-on detection of thymine DNA glycosylase activity." in: Biosensors & bioelectronics, Vol. 86, pp. 849-57, (2016) (PubMed).
: "TGFβ promotes mesenchymal phenotype of pancreatic cancer cells, in part, through epigenetic activation of VAV1." in: Oncogene, Vol. 36, Issue 16, pp. 2202-2214, (2016) (PubMed).
: "Crystal structure of thymine DNA glycosylase conjugated to SUMO-1." in: Nature, Vol. 435, Issue 7044, pp. 979-82, (2005) (PubMed).
: "Modification of the human thymine-DNA glycosylase by ubiquitin-like proteins facilitates enzymatic turnover." in: The EMBO journal, Vol. 21, Issue 6, pp. 1456-64, (2002) (PubMed).
: "Cloning and expression of human G/T mismatch-specific thymine-DNA glycosylase." in: The Journal of biological chemistry, Vol. 271, Issue 22, pp. 12767-74, (1996) (PubMed).
: "Efficient removal of uracil from G.U mispairs by the mismatch-specific thymine DNA glycosylase from HeLa cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 91, Issue 5, pp. 1642-6, (1994) (PubMed).
Aliases for TDG 抗体
thymine DNA glycosylase (TDG) 抗体thymine DNA glycosylase, tandem duplicate 1 (tdg.1) 抗体
putative g/t mismatch-specific thymine DNA glycosylase (Smp_149220) 抗体
G/T mismatch-specific thymine DNA glycosylase (Tsp_05734) 抗体
thymine DNA glycosylase S homeolog (tdg.S) 抗体
thymine DNA glycosylase (tdg) 抗体
thymine DNA glycosylase (Tdg) 抗体
thymine-DNA glycosylase (Tdg) 抗体
5-MCDG 抗体
E130317C12Rik 抗体
hTDG 抗体
JZA-3 抗体
Jza1 抗体
MGC82456 抗体
MGC89441 抗体
wu:fb44b11 抗体
zgc:110622 抗体
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