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TDG 抗体 (N-Term)

TDG 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB19893 unconjugated
产品编号 ABIN390559
发货至: 中国
  • 抗原 See all TDG 抗体
    TDG (Thymine-DNA Glycosylase (TDG))
    抗原表位
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 81-110, N-Term
    适用
    • 46
    • 19
    • 12
    • 2
    • 1
    人, 小鼠
    宿主
    • 37
    • 10
    克隆类型
    • 40
    • 8
    多克隆
    标记
    • 41
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TDG antibody is un-conjugated
    应用范围
    • 37
    • 11
    • 11
    • 8
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This TDG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-110 amino acids from the N-terminal region of human TDG.
    克隆位点
    RB19893
    亚型
    Ig Fraction
    Top Product
    Discover our top product TDG Primary Antibody
  • 应用备注
    WB: 1:1000. FC: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    TDG (Thymine-DNA Glycosylase (TDG))
    别名
    TDG (TDG 产品)
    别名
    5-MCDG antibody, wu:fb44b11 antibody, zgc:110622 antibody, MGC82456 antibody, MGC89441 antibody, E130317C12Rik antibody, JZA-3 antibody, Jza1 antibody, hTDG antibody, thymine DNA glycosylase antibody, thymine DNA glycosylase, tandem duplicate 1 antibody, putative g/t mismatch-specific thymine DNA glycosylase antibody, G/T mismatch-specific thymine DNA glycosylase antibody, thymine DNA glycosylase S homeolog antibody, thymine-DNA glycosylase antibody, TDG antibody, tdg.1 antibody, Smp_149220 antibody, Tsp_05734 antibody, tdg.S antibody, tdg antibody, Tdg antibody
    背景
    The protein TDG belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine.
    分子量
    46053
    基因ID
    6996
    NCBI登录号
    NP_003202
    UniProt
    Q13569
    途径
    DNA Damage Repair, Chromatin Binding
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