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TDG 抗体

(Thymine-DNA Glycosylase (TDG))
The protein encoded by this gene belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. This gene may have a pseudogene in the p arm of chromosome 12. [provided by RefSeq, Jul 2008].

52 results

TDG 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7153379
 
TDG 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
产品编号 ABIN520808
 
TDG 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6258811
 
TDG 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7256880
 
TDG 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN520809
 
TDG 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6972851
 
TDG 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
Pubmed 4 references
产品编号 ABIN967162
 
TDG 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB19894 unconjugated
产品编号 ABIN390560
 
TDG 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB19893 unconjugated
产品编号 ABIN390559
 
TDG 适用: 人, 小鼠, 大鼠, Cow WB, IF, IC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7299484
 
TDG 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6280165
 
TDG 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7647031
 
TDG 适用: 人 WB, IHC, ICC, IP 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN7647032
 
TDG 适用: 人, 小鼠, 大鼠 WB, ELISA, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7119947
 
TDG 适用: 人, 小鼠, 大鼠, Cow WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2573729
 
TDG 适用: 人 WB, IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7455026
 
TDG 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7571695
 
TDG 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1841313
 
TDG 适用: 人 WB, FACS 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1841314
 
TDG 适用: 人, 小鼠, 大鼠 WB, IF, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2892156
 
  • 类型 Primary
    • Primary
  • 应用范围
    • Western Blotting (WB)
    • ELISA
    • Immunofluorescence (IF)
    • Immunohistochemistry (IHC)
    • Immunocytochemistry (ICC)
    • Immunoprecipitation (IP)
    • Flow Cytometry (FACS)
    • Enzyme Immunoassay (EIA)
    • Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    • Immunochromatography (IC)
    • Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
  • 适用
    • Human
    • Mouse
    • Rat
    • Cow
    • Monkey
  • 论文引用
  • 图像
  • Preservative free only
  • Carrier free only
  • 抗体来源
    • Rabbit
    • Mouse
  • 克隆形成能力
    • Polyclonal
    • Monoclonal
  • 克隆
    • AT2F7
    • 1SJ-1F5
    • GT1142
    • GT1511
    • GT311
    • GT622
    • OTI3A12
    • OTI3C11
    • RB19893
    • RB19894
  • 抗原表位
    • AA 1-410
    • C-Term
    • Internal Region
    • N-Term
    • AA 141-410
    • AA 160-253
    • AA 281-310
    • AA 360-410
    • AA 81-110
    • AA 1-80
    • AA 115-343
    • AA 15-370
    • AA 31-80
    • Center
    • Lys90
    • ubLys330
  • 标记
    • 非结合性
    • Alexa Fluor 488
    • Alexa Fluor 555
    • Alexa Fluor 594
    • Alexa Fluor 647
    • Alexa Fluor 680
    • Alexa Fluor 750
    • Biotin
  • 抗体亚型
    • IgG
    • IgG1
    • Ig Fraction
    • IgG2b
    • IgG1 kappa
    • IgG2a
    • IgG2b kappa
  • Format
    • Liquid
    • Lyophilized
  • Grade
    • KO Validated
  • Supplier
    • antibodies-online
    • Signalway
    • USBio
    • Acris
    • Abbexa
    • Abcepta
    • OriGene
    • Abiocode
    • Assay Biotechnology Company, Inc.
    • Boster Bio
    • Cohesion Biosciences
    • ProteoGenix

Latest Publications for our TDG 抗体

Galanos, Pappas, Polyzos, Kotsinas, Svolaki, Giakoumakis, Glytsou, Pateras, Swain, Souliotis, Georgakilas, Geacintov, Scorrano, Lukas, Lukas, Livneh, Lygerou, Chowdhury, Sørensen, Bartek, Gorgoulis: "Mutational signatures reveal the role of RAD52 in p53-independent p21-driven genomic instability." in: Genome biology, Vol. 19, Issue 1, pp. 37, (2018) (PubMed).

Lin, Kang, Lu, Wang, Ma, Leung: "A G-quadruplex-selective luminescent probe with an anchor tail for the switch-on detection of thymine DNA glycosylase activity." in: Biosensors & bioelectronics, Vol. 86, pp. 849-57, (2016) (PubMed).

Huang, Lu, Ding, Chu, Hsu, Chen, Tsao, Chen, Lee, Shan, Chen: "TGFβ promotes mesenchymal phenotype of pancreatic cancer cells, in part, through epigenetic activation of VAV1." in: Oncogene, Vol. 36, Issue 16, pp. 2202-2214, (2016) (PubMed).

Baba, Maita, Jee, Uchimura, Saitoh, Sugasawa, Hanaoka, Tochio, Hiroaki, Shirakawa: "Crystal structure of thymine DNA glycosylase conjugated to SUMO-1." in: Nature, Vol. 435, Issue 7044, pp. 979-82, (2005) (PubMed).

Hardeland, Steinacher, Jiricny, Schär: "Modification of the human thymine-DNA glycosylase by ubiquitin-like proteins facilitates enzymatic turnover." in: The EMBO journal, Vol. 21, Issue 6, pp. 1456-64, (2002) (PubMed).

Neddermann, Gallinari, Lettieri, Schmid, Truong, Hsuan, Wiebauer, Jiricny: "Cloning and expression of human G/T mismatch-specific thymine-DNA glycosylase." in: The Journal of biological chemistry, Vol. 271, Issue 22, pp. 12767-74, (1996) (PubMed).

Neddermann, Jiricny: "Efficient removal of uracil from G.U mispairs by the mismatch-specific thymine DNA glycosylase from HeLa cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 91, Issue 5, pp. 1642-6, (1994) (PubMed).

Aliases for TDG 抗体

thymine DNA glycosylase (TDG) 抗体
thymine DNA glycosylase, tandem duplicate 1 (tdg.1) 抗体
putative g/t mismatch-specific thymine DNA glycosylase (Smp_149220) 抗体
G/T mismatch-specific thymine DNA glycosylase (Tsp_05734) 抗体
thymine DNA glycosylase S homeolog (tdg.S) 抗体
thymine DNA glycosylase (tdg) 抗体
thymine DNA glycosylase (Tdg) 抗体
thymine-DNA glycosylase (Tdg) 抗体
5-MCDG 抗体
E130317C12Rik 抗体
hTDG 抗体
JZA-3 抗体
Jza1 抗体
MGC82456 抗体
MGC89441 抗体
wu:fb44b11 抗体
zgc:110622 抗体
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