SSH1 抗体
(Slingshot Homolog 1 (SSH1))
The protein encoded by this gene belongs to the slingshot homolog (SSH) family of phosphatases, which regulate actin filament dynamics. The SSH proteins dephosphorylate and activate the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Cofilin is inactivated by kinases such as LIM domain kinase-1 (LIMK1), which may also be dephosphorylated and inactivated by SSH proteins. The SSH family thus appears to play a role in actin dynamics by reactivating cofilin proteins. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011].
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Latest Publications for our SSH1 抗体
: "Actin-depolymerizing factor cofilin-1 is necessary in maintaining mature podocyte architecture." in: The Journal of biological chemistry, Vol. 285, Issue 29, pp. 22676-88, (2010) (PubMed).
: "Pivotal Advance: PKCzeta is required for migration of macrophages." in: Journal of leukocyte biology, Vol. 85, Issue 6, pp. 911-8, (2009) (PubMed).
: "Pivotal Advance: PKCzeta is required for migration of macrophages." in: Journal of leukocyte biology, Vol. 85, Issue 6, pp. 911-8, (2009) (PubMed).
Aliases for SSH1 抗体
slingshot homolog 1 (Drosophila) (Ssh1) 抗体slingshot protein phosphatase 1 (SSH1) 抗体
AW551225 抗体
Gm1394 抗体
Gm1395 抗体
mSSH-1L 抗体
SSH-1 抗体
SSH1L 抗体
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