SRCAP 抗体
(Snf2-Related CREBBP Activator Protein (SRCAP))
This gene encodes the core catalytic component of the multiprotein chromatin-remodeling SRCAP complex. The encoded protein is an ATPase that is necessary for the incorporation of the histone variant H2A.Z into nucleosomes. It can function as a transcriptional activator in Notch-mediated, CREB-mediated and steroid receptor-mediated transcription. Mutations in this gene cause Floating-Harbor syndrome, a rare disorder characterized by short stature, language deficits and dysmorphic facial features. [provided by RefSeq, Feb 2012].
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4 results
SRCAP
适用: 人
ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro)
宿主: 兔
Polyclonal
unconjugated
Latest Publications for our SRCAP 抗体
: "The chromatin remodeling protein, SRCAP, is critical for deposition of the histone variant H2A.Z at promoters." in: The Journal of biological chemistry, Vol. 282, Issue 36, pp. 26132-9, (2007) (PubMed).Aliases for SRCAP 抗体
Snf2 related CREBBP activator protein (SRCAP) 抗体Snf2-related CREBBP activator protein (Srcap) 抗体
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