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SOCS2 抗体

(Suppressor of Cytokine Signaling 2 (SOCS2))
This gene encodes a member of the suppressor of cytokine signaling (SOCS) family. SOCS family members are cytokine-inducible negative regulators of cytokine receptor signaling via the Janus kinase/signal transducer and activation of transcription pathway (the JAK/STAT pathway). SOCS family proteins interact with major molecules of signaling complexes to block further signal transduction, in part, by proteasomal depletion of receptors or signal-transducing proteins via ubiquitination. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10, interferon (IFN)-gamma and by cytokine receptors such as growth horomone receptor. The protein encoded by this gene interacts with the cytoplasmic domain of insulin-like growth factor-1 receptor (IGF1R) and is thought to be involved in the regulation of IGF1R mediated cell signaling. This gene has pseudogenes on chromosomes 20 and 22. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012].

Active filters:

  • 抗原: SOCS2
  • Primary
Catalog no. 产品 适用 宿主 / 克隆类型 应用 价格和交货时间
ABIN6887106
Recombinant SOCS2 抗体 (Alexa Fluor 555) SOCS2 · Primary Antibody 人 兔 Monoclonal
  • 100 μL
发货至: 中国
ABIN6871043
Recombinant SOCS2 抗体 (Biotin) SOCS2 · Primary Antibody 人 兔 Monoclonal
  • 100 μL
发货至: 中国
ABIN6846853
Recombinant SOCS2 抗体 (Alexa Fluor 647) SOCS2 · Primary Antibody 人 兔 Monoclonal
  • 100 μL
发货至: 中国
ABIN6903169
Recombinant SOCS2 抗体 (Alexa Fluor 680) SOCS2 · Primary Antibody 人 兔 Monoclonal
  • 100 μL
发货至: 中国
ABIN6830790
Recombinant SOCS2 抗体 (Alexa Fluor 594) SOCS2 · Primary Antibody 人 兔 Monoclonal
  • 100 μL
发货至: 中国
ABIN6337636
SOCS2 抗体 SOCS2 · Primary Antibody 大鼠 小鼠 Monoclonal
  • WB (Western Blotting: 所列应用)
  • IHC (Immunohistochemistry: 所列应用)
  • IP (Immunoprecipitation: 所列应用)
  • IF/ICC (Immunofluorescence (fixed cells): 所列应用)
  • 1 mL
  • 20 μL
  • 50 μL
  • 100 μL
  • 200 μL
发货至: 中国
ABIN1453938
SOCS2 抗体 (AA 18-67) SOCS2 · Primary Antibody 人, 大鼠, 小鼠 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • IHC (Immunohistochemistry: 所列应用)
  • 100 μL
  • 20 μg
  • 50 μL
发货至: 中国
Primary Antibody
适用
人
宿主
兔
克隆形成能力
Monoclonal
标记
Alexa Fluor 555
蛋白类型
Recombinant Antibody
产品编号 ABIN6887106
Primary Antibody
适用
人
宿主
兔
克隆形成能力
Monoclonal
标记
Biotin
蛋白类型
Recombinant Antibody
产品编号 ABIN6871043
Primary Antibody
适用
人
宿主
兔
克隆形成能力
Monoclonal
标记
Alexa Fluor 647
蛋白类型
Recombinant Antibody
产品编号 ABIN6846853
Primary Antibody
适用
人
宿主
兔
克隆形成能力
Monoclonal
标记
Alexa Fluor 680
蛋白类型
Recombinant Antibody
产品编号 ABIN6903169
Primary Antibody
适用
人
宿主
兔
克隆形成能力
Monoclonal
标记
Alexa Fluor 594
蛋白类型
Recombinant Antibody
产品编号 ABIN6830790
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • IHC (Immunohistochemistry: 所列应用)
  • IP (Immunoprecipitation: 所列应用)
  • IF/ICC (Immunofluorescence (fixed cells): 所列应用)
适用
大鼠
宿主
小鼠
克隆形成能力
Monoclonal
标记
unconjugated
产品编号 ABIN6337636
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • IHC (Immunohistochemistry: 所列应用)
适用
人, 大鼠, 小鼠
宿主
兔
克隆形成能力
Polyclonal
标记
unconjugated
抗体亚型
IgG
抗原表位
AA 18-67
产品编号 ABIN1453938
100 μL (More quantities available)
发货至: 中国
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Latest Publications for our SOCS2 抗体

Shin, Riew, Park, Pak, Lee: "Expression of SOCS2 mRNA and protein in the ischemic core and penumbra after transient focal cerebral ischemia in rats." in: Cell and tissue research, Vol. 364, Issue 1, pp. 67-81, (2016) (PubMed).

Letellier, Schmitz, Baig, Beaume, Schwartz, Frasquilho, Antunes, Marcon, Nazarov, Vallar, Even, Haan: "Identification of SOCS2 and SOCS6 as biomarkers in human colorectal cancer." in: British journal of cancer, Vol. 111, Issue 4, pp. 726-35, (2014) (PubMed).

Zhu, Dai, Han, He, Mo, Chen, Chen, Wu, Yang, Jiang, Chen, Sun, Zhong: "Expression of SOCSs in human prostate cancer and their association in prognosis." in: Molecular and cellular biochemistry, Vol. 381, Issue 1-2, pp. 51-9, (2013) (PubMed).

Inagaki, Lin, Goetz, Mohammadi, Mangelsdorf, Kliewer: "Inhibition of growth hormone signaling by the fasting-induced hormone FGF21." in: Cell metabolism, Vol. 8, Issue 1, pp. 77-83, (2008) (PubMed).

Hamilton, Lin, Wang, Knowlton: "Effect of ovariectomy on cardiac gene expression: inflammation and changes in SOCS gene expression." in: Physiological genomics, Vol. 32, Issue 2, pp. 254-63, (2008) (PubMed).

Ransome, Turnley: "Analysis of neuronal subpopulations in mice over-expressing suppressor of cytokine signaling-2." in: Neuroscience, Vol. 132, Issue 3, pp. 673-87, (2005) (PubMed).

Greenhalgh, Bertolino, Asa, Metcalf, Corbin, Adams, Davey, Nicola, Hilton, Alexander: "Growth enhancement in suppressor of cytokine signaling 2 (SOCS-2)-deficient mice is dependent on signal transducer and activator of transcription 5b (STAT5b)." in: Molecular endocrinology (Baltimore, Md.), Vol. 16, Issue 6, pp. 1394-406, (2002) (PubMed).

Gregorieff, Pyronnet, Sonenberg, Veillette: "Regulation of SOCS-1 expression by translational repression." in: The Journal of biological chemistry, Vol. 275, Issue 28, pp. 21596-604, (2000) (PubMed).

Ram, Waxman: "SOCS/CIS protein inhibition of growth hormone-stimulated STAT5 signaling by multiple mechanisms." in: The Journal of biological chemistry, Vol. 274, Issue 50, pp. 35553-61, (2000) (PubMed).

Dey, Spence, Nissley, Furlanetto: "Interaction of human suppressor of cytokine signaling (SOCS)-2 with the insulin-like growth factor-I receptor." in: The Journal of biological chemistry, Vol. 273, Issue 37, pp. 24095-101, (1998) (PubMed).

Aliases for SOCS2 抗体

suppressor of cytokine signaling 2 (SOCS2) 抗体
suppressor of cytokine signaling 1 (Socs1) 抗体
suppressor of cytokine signaling 2 (Socs2) 抗体
suppressor of cytokine signaling 2 (socs2) 抗体
death domain-containing protein CRADD (LOC100716104) 抗体
suppressor of cytokine signaling 2 S homeolog (socs2.S) 抗体
8030460M17 抗体
AI527257 抗体
AW108012 抗体
CIS2 抗体
cis2 抗体
Cish1 抗体
Cish2 抗体
cish2 抗体
Cradd 抗体
D130043N08Rik 抗体
hg 抗体
JAB 抗体
si:dkey-202b22.1 抗体
Socs-1 抗体
SOCS-2 抗体
Socs-2 抗体
socs-2 抗体
socs2 抗体
Socs2 抗体
SSI-2 抗体
ssi-2 抗体
SSI2 抗体
ssi2 抗体
STATI2 抗体
stati2 抗体
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