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SOCS2 抗体 (AA 18-67)

The 兔 多克隆 anti-SOCS2 antibody (ABIN1453938) specifically detects SOCS2 in WB 和 IHC. The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN1453938
发货至: 中国
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Quick Overview for SOCS2 抗体 (AA 18-67) (ABIN1453938)

抗原

See all SOCS2 抗体
SOCS2 (Suppressor of Cytokine Signaling 2 (SOCS2))

适用

  • 64
  • 28
  • 9
  • 4
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
人, 大鼠, 小鼠

宿主

  • 63
  • 3
兔

克隆类型

  • 44
  • 22
多克隆

标记

  • 26
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SOCS2 antibody is un-conjugated

应用范围

  • 38
  • 15
  • 14
  • 11
  • 10
  • 10
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 12
    • 8
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    AA 18-67

    原理

    SOCS-2 Antibody

    特异性

    SOCS-2 Polyclonal Antibody detects endogenous levels of SOCS-2 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    The antiserum was produced against synthesized peptide derived from human SOCS-2. AA range:18-67

    亚型

    IgG
  • 应用备注

    WB 1:500-2000,IHC 1:50-300

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    SOCS2 (Suppressor of Cytokine Signaling 2 (SOCS2))

    别名

    SOCS-2

    背景

    Synonyms: SOCS2, CIS2, SSI2, STATI2, Suppressor of cytokine signaling 2, SOCS-2, Cytokine-inducible SH2 protein 2, CIS-2, STAT-induced STAT inhibitor 2, SSI-2

    Background: This gene encodes a member of the suppressor of cytokine signaling (SOCS) family. SOCS family members are cytokine-inducible negative regulators of cytokine receptor signaling via the Janus kinase/signal transducer and activation of transcription pathway (the JAK/STAT pathway). SOCS family proteins interact with major molecules of signaling complexes to block further signal transduction, in part, by proteasomal depletion of receptors or signal-transducing proteins via ubiquitination. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10, interferon (IFN)-gamma and by cytokine receptors such as growth horomone receptor.The protein encoded by this gene interacts with the cytoplasmic domain of insulin-like growth factor-1 receptor (IGF1R) and is thought to be involved in the regulation of IGF1R mediated cell signaling. This gene has

    Gene Name: SOCS2

    Protein Name: Suppressor of cytokine signaling 2

    分子量

    22 kDa

    基因ID

    8835

    OMIM

    605117

    UniProt

    O14508

    途径

    JAK/STAT Signaling, Response to Growth Hormone Stimulus
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