SLC8A1 抗体
(Solute Carrier Family 8 (Sodium/calcium Exchanger), Member 1 (SLC8A1))
In cardiac myocytes, Ca(2+) concentrations alternate between high levels during contraction and low levels during relaxation. The increase in Ca(2+) concentration during contraction is primarily due to release of Ca(2+) from intracellular stores. However, some Ca(2+) also enters the cell through the sarcolemma (plasma membrane). During relaxation, Ca(2+) is sequestered within the intracellular stores. To prevent overloading of intracellular stores, the Ca(2+) that entered across the sarcolemma must be extruded from the cell. The Na(+)-Ca(2+) exchanger is the primary mechanism by which the Ca(2+) is extruded from the cell during relaxation. In the heart, the exchanger may play a key role in digitalis action. The exchanger is the dominant mechanism in returning the cardiac myocyte to its resting state following excitation.[supplied by OMIM, Apr 2004].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| SLC8A1 抗体 (AA 801-900) (Cy3) | 人 | 兔 Polyclonal |
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| SLC8A1 抗体 (AA 407-718) | 人 | 兔 Polyclonal |
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| SLC8A1 抗体 (AA 270-350) | 人, 大鼠, 小鼠 | 兔 Polyclonal |
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| SLC8A1 抗体 (AA 46-95) | 人, 大鼠, 小鼠, 犬, Cow, 兔, 豚鼠, 马, 斑马鱼, Bat, 小鸡, 猴 | 兔 Polyclonal |
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| SLC8A1 抗体 (AA 296-325) (Biotin) | 人 | 兔 Polyclonal |
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| SLC8A1 抗体 (AA 296-325) (HRP) | 人 | 兔 Polyclonal |
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| SLC8A1 抗体 (AA 296-325) (FITC) | 人 | 兔 Polyclonal |
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| SLC8A1 抗体 (AA 296-325) (PE) | 人 | 兔 Polyclonal |
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| SLC8A1 抗体 (AA 296-325) (APC) | 人 | 兔 Polyclonal |
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| SLC8A1 抗体 (AA 336-381) | 人, 大鼠, 小鼠 | 兔 Polyclonal |
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| SLC8A1 抗体 (AA 296-325) | 人 | 兔 Polyclonal |
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| SLC8A1 抗体 (Cytoplasmic Domain) | 大鼠, 小鼠, 犬, Cat | 兔 Polyclonal |
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| SLC8A1 抗体 | 犬 | 兔 Polyclonal |
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| SLC8A1 抗体 | 犬 | 小鼠 Monoclonal |
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| SLC8A1 抗体 (N-Term) | 人 | 兔 Polyclonal |
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| SLC8A1 抗体 (N-Term) | 大鼠 | 兔 Polyclonal |
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| SLC8A1 抗体 | 人, 大鼠, 小鼠 | 兔 Monoclonal |
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| SLC8A1 抗体 (3rd Intracellular Loop) | 人, 大鼠, 小鼠 | 兔 Polyclonal |
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| SLC8A1 抗体 (N-Term) | 人, 大鼠, 小鼠, 犬, Cow, 兔, 豚鼠, 马, 斑马鱼 | 兔 Polyclonal |
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| SLC8A1 抗体 (AA 301-686) (Biotin) | 人 | 兔 Polyclonal |
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Primary Antibody
- WB (Western Blotting: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Cy3
- 抗体亚型
- IgG
- 抗原表位
- AA 801-900
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 407-718
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人, 大鼠, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 270-350
Primary Antibody
- WB (Western Blotting: 所列应用)
- 适用
- 人, 大鼠, 小鼠, 犬, Cow, 兔, 豚鼠, 马, 斑马鱼, Bat, 小鸡, 猴
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 46-95
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Biotin
- 抗体亚型
- IgG
- 抗原表位
- AA 296-325
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- HRP
- 抗体亚型
- IgG
- 抗原表位
- AA 296-325
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- FITC
- 抗体亚型
- IgG
- 抗原表位
- AA 296-325
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- PE
- 抗体亚型
- IgG
- 抗原表位
- AA 296-325
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- APC
- 抗体亚型
- IgG
- 抗原表位
- AA 296-325
Primary Antibody
- WB (Western Blotting: 所列应用)
- 适用
- 人, 大鼠, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 336-381
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 296-325
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 大鼠, 小鼠, 犬, Cat
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- Cytoplasmic Domain
Primary Antibody
- WB (Western Blotting: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- N-Term
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- N-Term
Primary Antibody
- M (Molecule: 有验证图片)
- WB (Western Blotting: 所列应用)
- IF (Immunofluorescence: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 质量等级
- Carrier-free
- 适用
- 人, 大鼠, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- 3rd Intracellular Loop, AA 308-320
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人, 大鼠, 小鼠, 犬, Cow, 兔, 豚鼠, 马, 斑马鱼
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- N-Term
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Biotin
- 抗体亚型
- IgG
- 抗原表位
- AA 301-686
Latest Publications for our SLC8A1 抗体
: "Effectiveness of gene delivery systems for pluripotent and differentiated cells." in: Molecular therapy. Methods & clinical development, Vol. 2, pp. 14067, (2015) (PubMed).
: "Small-molecule activation of SERCA2a SUMOylation for the treatment of heart failure." in: Nature communications, Vol. 6, pp. 7229, (2015) (PubMed).
: "Arrhythmogenic coupling between the Na+ -Ca2+ exchanger and inositol 1,4,5-triphosphate receptor in rat pulmonary vein cardiomyocytes." in: Journal of molecular and cellular cardiology, Vol. 52, Issue 5, pp. 988-97, (2012) (PubMed).
: "Inverse correlation between the extent of N-glycan branching and intercellular adhesion in epithelia. Contribution of the Na,K-ATPase beta1 subunit." in: The Journal of biological chemistry, Vol. 283, Issue 4, pp. 2192-202, (2008) (PubMed).
: "Na+/Ca2+ exchange inhibition protects the rat heart from ischemia-reperfusion injury by blocking energy-wasting processes." in: American journal of physiology. Heart and circulatory physiology, Vol. 288, Issue 4, pp. H1699-707, (2005) (PubMed).
: "Cleavage of the plasma membrane Na+/Ca2+ exchanger in excitotoxicity." in: Cell, Vol. 120, Issue 2, pp. 275-85, (2005) (PubMed).
: "Neurodegeneration: cellular defences destroyed." in: Nature, Vol. 433, Issue 7027, pp. 696-8, (2005) (PubMed).
: "Dietary calcium deficiency increases Ca2+ uptake and Ca2+ extrusion mechanisms in chick enterocytes." in: Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, Vol. 139, Issue 2, pp. 133-41, (2004) (PubMed).
: "Cardiac neuronal nitric oxide synthase isoform regulates myocardial contraction and calcium handling." in: Circulation research, Vol. 92, Issue 5, pp. e52-9, (2003) (PubMed).
: "Regulation of phosphatidylinositol-4,5-biphosphate bound to the bovine cardiac Na+/Ca2+ exchanger." in: Annals of the New York Academy of Sciences, Vol. 976, pp. 288-99, (2002) (PubMed).
: "Small-molecule activation of SERCA2a SUMOylation for the treatment of heart failure." in: Nature communications, Vol. 6, pp. 7229, (2015) (PubMed).
: "Arrhythmogenic coupling between the Na+ -Ca2+ exchanger and inositol 1,4,5-triphosphate receptor in rat pulmonary vein cardiomyocytes." in: Journal of molecular and cellular cardiology, Vol. 52, Issue 5, pp. 988-97, (2012) (PubMed).
: "Inverse correlation between the extent of N-glycan branching and intercellular adhesion in epithelia. Contribution of the Na,K-ATPase beta1 subunit." in: The Journal of biological chemistry, Vol. 283, Issue 4, pp. 2192-202, (2008) (PubMed).
: "Na+/Ca2+ exchange inhibition protects the rat heart from ischemia-reperfusion injury by blocking energy-wasting processes." in: American journal of physiology. Heart and circulatory physiology, Vol. 288, Issue 4, pp. H1699-707, (2005) (PubMed).
: "Cleavage of the plasma membrane Na+/Ca2+ exchanger in excitotoxicity." in: Cell, Vol. 120, Issue 2, pp. 275-85, (2005) (PubMed).
: "Neurodegeneration: cellular defences destroyed." in: Nature, Vol. 433, Issue 7027, pp. 696-8, (2005) (PubMed).
: "Dietary calcium deficiency increases Ca2+ uptake and Ca2+ extrusion mechanisms in chick enterocytes." in: Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, Vol. 139, Issue 2, pp. 133-41, (2004) (PubMed).
: "Cardiac neuronal nitric oxide synthase isoform regulates myocardial contraction and calcium handling." in: Circulation research, Vol. 92, Issue 5, pp. e52-9, (2003) (PubMed).
: "Regulation of phosphatidylinositol-4,5-biphosphate bound to the bovine cardiac Na+/Ca2+ exchanger." in: Annals of the New York Academy of Sciences, Vol. 976, pp. 288-99, (2002) (PubMed).
Aliases for SLC8A1 抗体
solute carrier family 8 member A1 (SLC8A1) 抗体solute carrier family 8 (sodium/calcium exchanger), member 1 (Slc8a1) 抗体
solute carrier family 8 member A1 (Slc8a1) 抗体
solute carrier family 8 (sodium/calcium exchanger), member 1b (slc8a1b) 抗体
sodium/calcium exchanger 1 (Tsp_07038) 抗体
AI852629 抗体
AV344025 抗体
D930008O12Rik 抗体
Ncx 抗体
NCX1 抗体
Ncx1 抗体
ncx1n 抗体
SLC8A1 抗体
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