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SLC9A4 抗体

(Solute Carrier Family 9 (Sodium/hydrogen Exchanger), Member 4 (SLC9A4))

Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction. May play a specialized role in the kidney in rectifying cell volume in response to extreme fluctuations of hyperosmolar-stimulated cell shrinkage. Is relatively amiloride and ethylisopropylamiloride (EIPA) insensitive. Can be activated under conditions of hyperosmolar-induced cell shrinkage in a sustained intracellular acidification-dependence manner. Activated by 4,4'-diisothiocyanostilbene-2,2'-disulfonic acid (DIDS) in a sustained intracellular acidification-dependence manner. Affects potassium/proton exchange as well as sodium/proton and lithium/proton exchange. In basolateral cell membrane, participates in homeostatic control of intracellular pH, and may play a role in proton extrusion in order to achieve transepithelial HCO3(-) secretion. In apical cell membrane may be involved in mediating sodium absorption. Requires for normal levels of gastric acid secretion, secretory membrane development, parietal cell maturation and/or differentiation and at least secondarily for chief cell differentiation.

recommended

SLC9A4 抗体 (C-Term) (ABIN3172632)

SLC9A4 适用: 大鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated

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Popular SLC9A4 抗体

Product

Reactivity

Application

Validations

Cat. No.

Quantity

Datasheet

anti-SLC9A4 抗体 (C-Term)

Reactivity Rat

Application ELISA, WB

Validations

Cat. No. ABIN3172632

Quantity 100 μg

Datasheet Datasheet

Latest Publications for our SLC9A4 抗体

Hadsell, Hadsell, Rijnkels, Carcamo-Bahena, Wei, Williamson, Grusak: "In silico mapping of quantitative trait loci (QTL) regulating the milk ionome in mice identifies a milk iron locus on chromosome 1." in: Mammalian genome : official journal of the International Mammalian Genome Society, Vol. 29, Issue 9-10, pp. 632-655, (2019) (PubMed).

Aliases for SLC9A4 抗体

solute carrier family 9 member A4 (SLC9A4) 抗体
solute carrier family 9 member A4 (slc9a4) 抗体
solute carrier family 9 (sodium/hydrogen exchanger), member 4 (Slc9a4) 抗体
solute carrier family 9 member A4 (Slc9a4) 抗体
AW990558 抗体
D730009J23Rik 抗体
NHE4 抗体
Nhe4 抗体
SLC9A2 抗体

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