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SIRT1 抗体

(Sirtuin 1 (SIRT1))

SIRT1 (Sirtuin 1) is a protein that plays a role in regulating metabolism and has been implicated in the development and progression of obesity. Several studies have investigated the potential of targeting SIRT1 as a therapeutic strategy for obesity.

Research has shown that SIRT1 is involved in the regulation of nutrient sensing and can modulate lipid and glucose metabolism. It has been found to protect against high-fat diet-induced metabolic damage and hepatic lipid accumulation. SIRT1 has also been shown to promote lipid metabolism and mitochondrial function, which are important processes in adipogenesis and obesity.

In addition, SIRT1 has been found to counteract aging- and obesity-related diseases by deacetylating many proteins. It has been suggested that targeting SIRT1 activity in the brain may show promise for the treatment of obesity and associated metabolic disorders.

SIRT1 antibodies are essential research tools for better understanding the role of SIRT1 in in regulating metabolism, lipid metabolism, and mitochondrial function.

178 results :

SIRT1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
Pubmed 5 references
产品编号 ABIN729853
 
SIRT1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 7B7 unconjugated
Pubmed 3 references
产品编号 ABIN565071
 
SIRT1 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6147784
 
SIRT1 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB50965 unconjugated
Pubmed 1 reference
产品编号 ABIN6242824
 
SIRT1 适用: 人 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 1F3 unconjugated
Pubmed 2 references
产品编号 ABIN969396
 
KO Validated SIRT1 适用: 人 WB, IHC, IP, IF, ChIP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7270322
 
SIRT1 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 马, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
Pubmed 5 references
产品编号 ABIN2779607
 
SIRT1 适用: 人, 小鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3032583
 
SIRT1 适用: 人 WB, IF, IHC (p), EIA 宿主: 小鼠 Monoclonal 7B7 unconjugated
产品编号 ABIN614713
 
SIRT1 适用: 人, 小鼠, 大鼠, 犬 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
Pubmed 4 references
产品编号 ABIN745658
 
SIRT1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7435913
 
SIRT1 适用: 人 IF (cc), IHC (p) 宿主: 兔 Monoclonal 6H5 unconjugated
产品编号 ABIN5557342
 
SIRT1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7160851
 
SIRT1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7435916
 
SIRT1 适用: 人 IHC, ELISA, IF 宿主: 兔 Monoclonal 9E9 unconjugated Recombinant Antibody
产品编号 ABIN7127809
 
SIRT1 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6265090
 
SIRT1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6254894
 
SIRT1 适用: 人, 小鼠, 大鼠, 犬, 兔, 猴, Cow, 豚鼠, 马, 斑马鱼, Bat, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN214144
 
Verified SIRT1 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN625834
 
Verified SIRT1 适用: 小鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN185702
 
  • 类型 Primary
    • Primary
  • 应用范围
    • Western Blotting (WB)
    • Immunohistochemistry (IHC)
    • ELISA
    • Flow Cytometry (FACS)
    • Immunofluorescence (Cultured Cells) (IF (cc))
    • Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    • Immunoprecipitation (IP)
    • Immunocytochemistry (ICC)
    • Immunofluorescence (IF)
    • Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    • Immunohistochemistry (Frozen Sections) (IHC (fro))
    • Enzyme Immunoassay (EIA)
    • Immunofluorescence (fixed cells) (IF/ICC)
    • Chromatin Immunoprecipitation (ChIP)
    • Radioimmunoassay (RIA)
    • Immunochromatography (IC)
    • Proximity Ligation Assay (PLA)
    • Coating (Coat)
  • 适用
    • Human
    • Mouse
    • Rat
    • Dog
    • Monkey
    • Rabbit
    • Chicken
    • Cow
    • Guinea Pig
    • Horse
    • Zebrafish (Danio rerio)
    • Bat
    • Pig
  • 论文引用
  • 图像
  • Preservative free only
  • Carrier free only
  • 抗体来源
    • Rabbit
    • Mouse
    • Chicken
    • Goat
    • Sheep
  • 克隆形成能力
    • Polyclonal
    • Monoclonal
  • 克隆
    • C2
    • 1089CT5-3-1
    • 1F3
    • 7B7
    • 9E9
    • D4
    • 2G1-F7
    • 2G10-F4-D9
    • 3C7
    • 6A1
    • 6H5
    • FDA-19
    • GG-19
    • HAI-19
    • PT0158R
    • PT0764R
    • R06-4K9
    • RB50965
  • 抗原表位
    • pSer47
    • AA 101-200
    • AA 551-650
    • AA 244-498
    • pThr530
    • C-Term
    • AA 2-747
    • AA 254-495
    • N-Term
    • AA 456-555
    • AA 236-490
    • AA 238-482
    • AA 25-75
    • AA 566-601
    • Ser47
    • AA 1-180
    • AA 1-490
    • AA 112-311
    • AA 13-62
    • AA 142-533
    • AA 194-747
    • AA 207-256
    • AA 30-110
    • AA 41-90
    • AA 448-747
    • AA 551-599
    • AA 577-590
    • AA 581-630
    • AA 587-621
    • AA 686-721
    • AA 700-747
    • Internal Region
    • Tyr631
    • pSer27
  • 标记
    • 非结合性
    • Biotin
    • FITC
    • Alexa Fluor 488
    • Alexa Fluor 555
    • Alexa Fluor 594
    • Alexa Fluor 647
    • Alexa Fluor 680
    • Alexa Fluor 750
    • HRP
    • PE
    • AbBy Fluor® 350
    • AbBy Fluor® 488
    • AbBy Fluor® 555
    • AbBy Fluor® 594
    • AbBy Fluor® 647
    • AbBy Fluor® 680
    • AbBy Fluor® 750
    • Cy3
    • Cy5
    • Cy5.5
    • Cy7
    • APC
    • PerCP
  • 抗体亚型
    • IgG
    • IgG1
    • Ig Fraction
    • IgG1 kappa
    • IgG3 kappa
    • kappa
    • IgG2b
    • IgG2b kappa
    • IgY
  • 蛋白类型
    • Recombinant Antibody
  • Format
    • Liquid
    • Lyophilized
  • Grade
    • Verified
    • KO Validated
  • Supplier
    • antibodies-online
    • Signalway
    • Biomatik
    • Assaypro
    • Abbexa
    • Boster Bio
    • NSJ Bioreagents
    • FabGennix
    • Acris
    • Rockland
    • Abcepta
    • Active Motif
    • Angio-Proteomie
    • Assay Biotechnology Company, Inc.
    • Aviva Systems Biology
    • Cloud-Clone
    • Cohesion Biosciences
    • Elabscience

Latest Publications for our SIRT1 抗体

Zbroch, Bazyluk, Malyszko, Koc-Zorawska, Rydzewska-Rosolowska, Kakareko, Hryszko: "The Serum Concentration of Anti-Aging Proteins, Sirtuin1 and αKlotho in Patients with End-Stage Kidney Disease on Maintenance Hemodialysis." in: Clinical interventions in aging, Vol. 15, pp. 387-393, (2020) (PubMed).

Yang, Wang, He, Liu, Chen, Wang, Wang, Wang: "Trimetazidine Inhibits Renal Tubular Epithelial Cells to Mesenchymal Transition in Diabetic Rats via Upregulation of Sirt1." in: Frontiers in pharmacology, Vol. 11, pp. 1136, (2020) (PubMed).

Ascenzi, Barberi, Dobrowolny, Villa Nova Bacurau, Nicoletti, Rizzuto, Rosenthal, Scicchitano, Musarò: "Effects of IGF-1 isoforms on muscle growth and sarcopenia." in: Aging cell, Vol. 18, Issue 3, pp. e12954, (2019) (PubMed).

Takata, Sakasai-Sakai, Takino, Takeuchi: "Evidence for Toxic Advanced Glycation End-Products Generated in the Normal Rat Liver." in: Nutrients, Vol. 11, Issue 7, (2019) (PubMed).

Yanes, Zhang, Shen, Weyand, Goronzy: "Metabolic reprogramming in memory CD4 T cell responses of old adults." in: Clinical immunology (Orlando, Fla.), Vol. 207, pp. 58-67, (2019) (PubMed).

Zhang, Abdukerim, Abilailieti, Tang, Ling, Pan: "The protective effects of orexin a against high glucose-induced activation of NLRP3 inflammasome in human vascular endothelial cells." in: Archives of biochemistry and biophysics, Vol. 672, pp. 108052, (2019) (PubMed).

Piao, Zhao, Zhu, Inoue, Shibata, Lei, Hu, Yu, Yang, Wu, Xu, Okumura, Ouchi, Murohara, Kuzuya, Cheng: "Chronic Psychological Stress Accelerates Vascular Senescence and Impairs Ischemia-Induced Neovascularization: The Role of Dipeptidyl Peptidase-4/Glucagon-Like Peptide-1-Adiponectin Axis." in: Journal of the American Heart Association, Vol. 6, Issue 10, (2018) (PubMed).

Zang, Fan, Chen, Huang, Qin: "Improvement of Lipid and Glucose Metabolism by Capsiate in Palmitic Acid-Treated HepG2 Cells via Activation of the AMPK/SIRT1 Signaling Pathway." in: Journal of agricultural and food chemistry, Vol. 66, Issue 26, pp. 6772-6781, (2018) (PubMed).

Zeng, Hu, He, Wang, Li, Xiong, Ye: "Hypothermic machine perfusion ameliorates inflammation during ischemia‑reperfusion injury via sirtuin‑1‑mediated deacetylation of nuclear factor‑κB p65 in rat livers donated after circulatory death." in: Molecular medicine reports, Vol. 16, Issue 6, pp. 8649-8656, (2018) (PubMed).

Zhang, Zhang, Guo, Zeng, Wu, Liu, He, Wang, Huang, Chen: "Sirt1 Protects Endothelial Cells against LPS-Induced Barrier Dysfunction." in: Oxidative medicine and cellular longevity, Vol. 2017, pp. 4082102, (2018) (PubMed).

Aliases for SIRT1 抗体

sirtuin 1 (SIRT1) 抗体
sirtuin 1 (SRT1) 抗体
sirtuin 1 (Sirt1) 抗体
sirtuin 1 L homeolog (sirt1.L) 抗体
AA673258 抗体
Sir2 抗体
SIR2 抗体
Sir2a 抗体
Sir2alpha 抗体
SIR2L1 抗体
sir2l1 抗体
sirtuin 抗体
sirtuin 1 抗体
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