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SIRT1 抗体 (AA 207-256)

SIRT1 适用: 人, 小鼠, 大鼠, 犬, 猴, 兔, Cow, 斑马鱼, 豚鼠, 马, Bat, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN214144
发货至: 中国
  • 抗原 See all SIRT1 抗体
    SIRT1 (Sirtuin 1 (SIRT1))
    抗原表位
    • 27
    • 16
    • 16
    • 9
    • 8
    • 7
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 207-256
    适用
    人, 小鼠, 大鼠, 犬, 猴, 兔, Cow, 斑马鱼, 豚鼠, 马, Bat, Pig
    宿主
    • 127
    • 20
    • 2
    • 2
    • 1
    克隆类型
    • 111
    • 41
    多克隆
    标记
    • 73
    • 14
    • 10
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    This SIRT1 antibody is un-conjugated
    应用范围
    • 124
    • 50
    • 50
    • 41
    • 39
    • 34
    • 26
    • 23
    • 19
    • 14
    • 9
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    品牌
    IHC-plus™
    特异性
    Human SIRT1
    预测反应
    Percent identity by BLAST analysis: Human, Mouse, Rat, Dog, Bovine, Rabbit, Horse, Pig, Guinea pig (100%) Xenopus (92%) Chicken (85%) Zebrafish (84%).
    纯化方法
    Immunoaffinity purified
    免疫原
    Synthetic peptide located between aa207-256 of human SIRT1 (Q96EB6, NP_036370). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Elephant, Dog, Bovine, Bat, Rabbit, Horse, Pig, Guinea pig (100%), Turkey, Xenopus (92%), Chicken (85%), Zebrafish (84%).

    Type of Immunogen: Synthetic peptide
    亚型
    IgG
    Top Product
    Discover our top product SIRT1 Primary Antibody
  • 应用备注
    Approved: IHC, IHC-P (5 μg/mL), WB (0.5 μg/mL)

    Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5 μg/mL.
    说明

    Target Species of Antibody: Human

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Distilled water
    浓度
    Lot specific
    缓冲液
    Lyophilized from PBS with 2 % sucrose
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C,-20 °C
    储存方法
    Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
    Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.
  • 抗原
    SIRT1 (Sirtuin 1 (SIRT1))
    别名
    SIRT1 / Sirtuin 1 (SIRT1 产品)
    别名
    sirtuin 1 antibody, AA673258 antibody, SIR2L1 antibody, Sir2 antibody, Sir2a antibody, Sir2alpha antibody, sir2l1 antibody, sirtuin antibody, SIR2 antibody, sirtuin 1 antibody, sirtuin 1 L homeolog antibody, SIRT1 antibody, SRT1 antibody, Sirt1 antibody, sirt1.L antibody
    背景
    Name/Gene ID: SIRT1
    Family: ADP-Ribosyltransferase

    Synonyms: SIRT1, SIR2-like protein 1, SIR2alpha, SIR2L1, Sirtuin 1, Sir2-like 1, Sirtuin type 1, HSIR2, HSIRT1
    基因ID
    23411
    NCBI登录号
    NP_036370
    UniProt
    Q96EB6
    途径
    MAPK Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Negative Regulation of intrinsic apoptotic Signaling
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