Signal-Regulatory Protein alpha 蛋白
(Signal-Regulatory Protein alpha (SIRPA))
Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of netrophils. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| SIRPA Protein (AA 31-373) (His tag,Fc Tag) | 人 | HEK-293 Cells |
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| SIRPA Protein (AA 31-370) (hFc-Avi Tag,Biotin) | 人 | HEK-293 Cells |
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| SIRPA Protein (AA 31-370) (His tag) | Cynomolgus | HEK-293 Cells |
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| SIRPA Protein (AA 31-373) (mFc Tag) | 人 | HEK-293 Cells |
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| SIRPA Protein (AA 31-369) (His tag) | Cynomolgus | HEK-293 Cells |
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| SIRPA Protein (AA 31-370) (His-Avi Tag,Biotin) | 人 | HEK-293 Cells |
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| SIRPA Protein (AA 31-370) (His tag) | 人 | HEK-293 Cells |
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| SIRPA Protein (AA 31-370) (His tag) | Cynomolgus | HEK-293 Cells |
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| SIRPA Protein (AA 32-373) (His tag) | 大鼠 | Baculovirus infected Insect Cells |
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| SIRPA Protein (AA 27-373) (His tag) | 人 | 大肠杆菌（E. Coli） |
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| SIRPA Protein (AA 32-373) (His tag) | 小鼠 | HEK-293 Cells |
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| SIRPA Protein (Fc Tag) | 小鼠 | HEK-293 Cells |
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| SIRPA Protein (His tag) | 小鼠 | HEK-293 Cells |
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| SIRPA Protein (AA 1-373) (His tag) | 大鼠 | HEK-293 Cells |
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| SIRPA Protein (AA 28-507) (GST tag) | 人 | 小麦胚 |
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| SIRPA Protein (AA 32-372) (mFc Tag) | 小鼠 | HEK-293 Cells |
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| SIRPA Protein (AA 32-373) (Fc Tag) | 小鼠 | HEK-293 Cells |
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| SIRPA Protein (AA 31-370) (Fc Tag) | 人 | HEK-293 Cells |
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| SIRPA Protein (AA 31-370) (Fc Tag,AVI tag,Biotin) | 人 | HEK-293 Cells |
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| SIRPA Protein (AA 32-373) (Fc Tag) | 小鼠 | HEK-293 Cells |
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Protein
- SDS (SDS-PAGE: 有验证图片)
- ELISA (ELISA: 有验证图片)
- AM (Affinity Measurement: 所列应用)
- ADA (Antibody Drug Assay: 所列应用)
- IA (Immunoassay: 所列应用)
- ScA (Screening Assay: 所列应用)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Protein
- SDS (SDS-PAGE: 有验证图片)
- ELISA (ELISA: 有验证图片)
- SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: 有验证图片)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 有验证图片)
- SPR (Surface Plasmon Resonance: 有验证图片)
- SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: 有验证图片)
- ELISA (ELISA: 有验证图片)
- 宿主
- Cynomolgus
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 有验证图片)
- ELISA (ELISA: 有验证图片)
- AM (Affinity Measurement: 所列应用)
- ADA (Antibody Drug Assay: 所列应用)
- IA (Immunoassay: 所列应用)
- ScA (Screening Assay: 所列应用)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Protein
- ELISA (ELISA: 有验证图片)
- WB (Western Blotting: 有验证图片)
- BLI (Bio-Layer Interferometry: 所列应用)
- 宿主
- Cynomolgus
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 生物活性
- Active
Protein
- ELISA (ELISA: 有验证图片)
- WB (Western Blotting: 有验证图片)
- BLI (Bio-Layer Interferometry: 所列应用)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 生物活性
- Active
Protein
- ELISA (ELISA: 有验证图片)
- WB (Western Blotting: 有验证图片)
- BLI (Bio-Layer Interferometry: 所列应用)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 有验证图片)
- ELISA (ELISA: 有验证图片)
1 reference - 宿主
- Cynomolgus
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- >95 % as determined by SDS-PAGE.
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 有验证图片)
- 宿主
- 大鼠
- 宿主
- Baculovirus infected Insect Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 %
Protein
- SDS (SDS-PAGE: 有验证图片)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
Protein
- SDS (SDS-PAGE: 有验证图片)
- AM (Affinity Measurement: 所列应用)
- ADA (Antibody Drug Assay: 所列应用)
- IA (Immunoassay: 所列应用)
- ScA (Screening Assay: 所列应用)
- 宿主
- 小鼠
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Protein
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- 宿主
- 小鼠
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 90 % as determined by reducing SDS-PAGE.
- 生物活性
- Active
Protein
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- 宿主
- 小鼠
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 生物活性
- Active
Protein
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- 宿主
- 大鼠
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 生物活性
- Active
Protein
- WB (Western Blotting: 有验证图片)
- 宿主
- 小鼠
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
Protein
- WB (Western Blotting: 有验证图片)
- 宿主
- 小鼠
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
Protein
- SDS (SDS-PAGE: 有验证图片)
- Bind (Binding Studies: 有验证图片)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- >95 % as determined by SDS-PAGE.
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 有验证图片)
- ELISA (ELISA: 有验证图片)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- >95 % as determined by SDS-PAGE.
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 有验证图片)
- ELISA (ELISA: 有验证图片)
- 宿主
- 小鼠
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- >95 % as determined by SDS-PAGE.
- 生物活性
- Active
Latest Publications for our Signal-Regulatory Protein alpha 蛋白
: "Novel SIRPα Antibodies That Induce Single-Agent Phagocytosis of Tumor Cells while Preserving T Cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 206, Issue 4, pp. 712-721, (2021) (PubMed).
: "Luteolin promotes macrophage-mediated phagocytosis by inhibiting CD47 pyroglutamation." in: Translational oncology, Vol. 14, Issue 8, pp. 101129, (2021) (PubMed).
: "Tumor-selective blockade of CD47 signaling with a CD47/PD-L1 bispecific antibody for enhanced anti-tumor activity and limited toxicity." in: Cancer immunology, immunotherapy : CII, (2020) (PubMed).
: "A novel fully human anti-CD47 antibody as a potential therapy for human neoplasms with good safety." in: Biochimie, Vol. 151, pp. 54-66, (2018) (PubMed).
: "Luteolin promotes macrophage-mediated phagocytosis by inhibiting CD47 pyroglutamation." in: Translational oncology, Vol. 14, Issue 8, pp. 101129, (2021) (PubMed).
: "Tumor-selective blockade of CD47 signaling with a CD47/PD-L1 bispecific antibody for enhanced anti-tumor activity and limited toxicity." in: Cancer immunology, immunotherapy : CII, (2020) (PubMed).
: "A novel fully human anti-CD47 antibody as a potential therapy for human neoplasms with good safety." in: Biochimie, Vol. 151, pp. 54-66, (2018) (PubMed).
Aliases for Signal-Regulatory Protein alpha 蛋白
signal regulatory protein alpha (SIRPA) 蛋白myeloperoxidase (MPO) 蛋白
signal-regulatory protein alpha (SIRPA) 蛋白
tyrosine-protein phosphatase non-receptor type substrate 1 (LOC458039) 蛋白
tyrosine-protein phosphatase non-receptor type substrate 1 (LOC100400378) 蛋白
tyrosine-protein phosphatase non-receptor type substrate 1 (LOC100590224) 蛋白
signal-regulatory protein alpha (Sirpa) 蛋白
AI835480 蛋白
BIT 蛋白
Bit 蛋白
CD172A 蛋白
CD172a 蛋白
MFR 蛋白
MYD-1 蛋白
P84 蛋白
PTPNS1 蛋白
Ptpns1 蛋白
SHP-1 蛋白
SHPS-1 蛋白
SHPS1 蛋白
SIRP 蛋白
SIRP-A1 蛋白
SIRP-B1 蛋白
SIRPA 蛋白
swc3 蛋白
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