Signal-Regulatory Protein alpha 蛋白
(Signal-Regulatory Protein alpha (SIRPA))
Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of netrophils. [provided by RefSeq, Jul 2008].
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MALS verified
SIRPA
宿主: Cynomolgus
宿主: HEK-293 Cells
Recombinant
>95 % as determined by SDS-PAGE.
MALS verified
SIRPA
宿主: 小鼠
宿主: HEK-293 Cells
Recombinant
>90 % as determined by SDS-PAGE.
SIRPA
宿主: 小鼠
宿主: 人细胞
Recombinant
Greater than 95 % as determined by reducing SDS-PAGE.
WB, SDS, ELISA, MS
Latest Publications for our Signal-Regulatory Protein alpha 蛋白
: "Novel SIRPα Antibodies That Induce Single-Agent Phagocytosis of Tumor Cells while Preserving T Cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 206, Issue 4, pp. 712-721, (2021) (PubMed).
: "Luteolin promotes macrophage-mediated phagocytosis by inhibiting CD47 pyroglutamation." in: Translational oncology, Vol. 14, Issue 8, pp. 101129, (2021) (PubMed).
: "Tumor-selective blockade of CD47 signaling with a CD47/PD-L1 bispecific antibody for enhanced anti-tumor activity and limited toxicity." in: Cancer immunology, immunotherapy : CII, (2020) (PubMed).
: "A novel fully human anti-CD47 antibody as a potential therapy for human neoplasms with good safety." in: Biochimie, Vol. 151, pp. 54-66, (2018) (PubMed).
: "Luteolin promotes macrophage-mediated phagocytosis by inhibiting CD47 pyroglutamation." in: Translational oncology, Vol. 14, Issue 8, pp. 101129, (2021) (PubMed).
: "Tumor-selective blockade of CD47 signaling with a CD47/PD-L1 bispecific antibody for enhanced anti-tumor activity and limited toxicity." in: Cancer immunology, immunotherapy : CII, (2020) (PubMed).
: "A novel fully human anti-CD47 antibody as a potential therapy for human neoplasms with good safety." in: Biochimie, Vol. 151, pp. 54-66, (2018) (PubMed).
Aliases for Signal-Regulatory Protein alpha 蛋白
signal regulatory protein alpha (SIRPA) 蛋白myeloperoxidase (MPO) 蛋白
signal-regulatory protein alpha (SIRPA) 蛋白
tyrosine-protein phosphatase non-receptor type substrate 1 (LOC458039) 蛋白
tyrosine-protein phosphatase non-receptor type substrate 1 (LOC100400378) 蛋白
tyrosine-protein phosphatase non-receptor type substrate 1 (LOC100590224) 蛋白
signal-regulatory protein alpha (Sirpa) 蛋白
AI835480 蛋白
BIT 蛋白
Bit 蛋白
CD172A 蛋白
CD172a 蛋白
MFR 蛋白
MYD-1 蛋白
P84 蛋白
PTPNS1 蛋白
Ptpns1 蛋白
SHP-1 蛋白
SHPS-1 蛋白
SHPS1 蛋白
SIRP 蛋白
SIRP-A1 蛋白
SIRP-B1 蛋白
SIRPA 蛋白
swc3 蛋白
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