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Shugoshin 抗体

(Shugoshin 1 (SGOL1))
Plays a central role in chromosome cohesion during mitosis by preventing premature dissociation of cohesin complex from centromeres after prophase, when most of cohesin complex dissociates from chromosomes arms. May act by preventing phosphorylation of the stag2 subunit of cohesin complex at the centromere, ensuring cohesin persistence at centromere until cohesin cleavage by espl1/separase at anaphase. May regulate kinetochore microtubule stability in mitosis, possibly to sense tension on mitotic chromosomes.

42 results :

SGOL1 适用: 人 ELISA, WB, IP 宿主: 小鼠 Monoclonal 3C11 unconjugated
Pubmed 9 references
产品编号 ABIN566873
 
SGOL1 适用: 人 ELISA, WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7169545
 
SGOL1 适用: Schizosaccharomyces pombe WB, IF 宿主: 兔 Polyclonal unconjugated
Pubmed 3 references
产品编号 ABIN2452123
 
SGOL1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN531036
 
SGOL1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7270288
 
SGOL1 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7188085
 
SGOL1 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7258968
 
SGOL1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
产品编号 ABIN531035
 
SGOL1 适用: 人, 小鼠, 大鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6259304
 
SGOL1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6749951
 
SGOL1 适用: 人, 小鼠 ELISA, WB, IF/ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6090168
 
SGOL1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7182664
 
SGOL1 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6282517
 
SGOL1 适用: 人 ELISA 宿主: 兔 Polyclonal Biotin
产品编号 ABIN7169546
 
SGOL1 适用: 人 ELISA 宿主: 兔 Polyclonal HRP
产品编号 ABIN7169548
 
SGOL1 适用: 人 宿主: 兔 Polyclonal FITC
产品编号 ABIN7169547
 
SGOL1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6287809
 
SGOL1 适用: 人, 小鼠, 大鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7119043
 
SGOL1 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7464591
 
SGOL1 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2571046
 
  • 类型 Primary
    • Primary
  • 应用范围
    • Western Blotting (WB)
    • ELISA
    • Immunofluorescence (IF)
    • Immunohistochemistry (IHC)
    • Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    • Immunoprecipitation (IP)
    • Immunocytochemistry (ICC)
    • Immunofluorescence (fixed cells) (IF/ICC)
  • 适用
    • Human
    • Mouse
    • Rat
    • C. elegans
    • Horse
    • Schizosaccharomyces pombe
  • 论文引用
  • 图像
  • Preservative free only
  • Carrier free only
  • 抗体来源
    • Rabbit
    • Mouse
  • 克隆形成能力
    • Polyclonal
    • Monoclonal
  • 克隆
    • 3C11
    • RB36785
  • 抗原表位
    • AA 260-439
    • AA 339-367
    • AA 1-292
    • Internal Region
    • pSer14
    • AA 1-293
    • AA 1-50
    • AA 1-80
    • AA 10-100
    • AA 240-320
    • AA 271-320
    • AA 338-367
    • AA 395-444
    • C-Term
    • Center
    • N-Term
  • 标记
    • 非结合性
    • FITC
    • Biotin
    • HRP
    • APC
    • Alexa Fluor 488
    • Alexa Fluor 555
    • Alexa Fluor 594
    • Alexa Fluor 647
    • Alexa Fluor 680
    • Alexa Fluor 750
    • PE
  • 抗体亚型
    • IgG
    • Ig Fraction
    • IgG2a
    • IgG2a kappa
  • Format
    • Liquid
    • Lyophilized
  • Supplier
    • antibodies-online
    • Signalway
    • USBio
    • Abbexa
    • Assay Biotechnology Company, Inc.
    • Abcepta
    • Aviva Systems Biology
    • BioAcademia
    • Biomatik
    • Boster Bio
    • Enogene Biotech

Latest Publications for our Shugoshin 抗体

Nijenhuis, Vallardi, Teixeira, Kops, Saurin: "Negative feedback at kinetochores underlies a responsive spindle checkpoint signal." in: Nature cell biology, Vol. 16, Issue 12, pp. 1257-64, (2014) (PubMed).

Nobumori, Shouse, Wu, Lee, Shen, Liu: "B56? tumor-associated mutations provide new mechanisms for B56?-PP2A tumor suppressor activity." in: Molecular cancer research : MCR, Vol. 11, Issue 9, pp. 995-1003, (2013) (PubMed).

Wang, Mayer, Stemmann, Nigg: "Centromere DNA decatenation depends on cohesin removal and is required for mammalian cell division." in: Journal of cell science, Vol. 123, Issue Pt 5, pp. 806-13, (2010) (PubMed).

Shouse, Nobumori, Liu: "A B56gamma mutation in lung cancer disrupts the p53-dependent tumor-suppressor function of protein phosphatase 2A." in: Oncogene, Vol. 29, Issue 27, pp. 3933-41, (2010) (PubMed).

Nozawa, Nagao, Masuda, Iwasaki, Hirota, Nozaki, Kimura, Obuse: "Human POGZ modulates dissociation of HP1alpha from mitotic chromosome arms through Aurora B activation." in: Nature cell biology, Vol. 12, Issue 7, pp. 719-27, (2010) (PubMed).

Garcia-Cruz, Brieño, Roig, Grossmann, Velilla, Pujol, Cabero, Pessarrodona, Barbero, Garcia Caldés: "Dynamics of cohesin proteins REC8, STAG3, SMC1 beta and SMC3 are consistent with a role in sister chromatid cohesion during meiosis in human oocytes." in: Human reproduction (Oxford, England), Vol. 25, Issue 9, pp. 2316-27, (2010) (PubMed).

Hayashi-Takanaka, Yamagata, Nozaki, Kimura: "Visualizing histone modifications in living cells: spatiotemporal dynamics of H3 phosphorylation during interphase." in: The Journal of cell biology, Vol. 187, Issue 6, pp. 781-90, (2009) (PubMed).

Yamagishi, Sakuno, Shimura, Watanabe: "Heterochromatin links to centromeric protection by recruiting shugoshin." in: Nature, Vol. 455, Issue 7210, pp. 251-5, (2008) (PubMed).

Fu, Ding, Yuan, Aikhionbare, Yao, Cai, Jiang, Yao: "Phosphorylation of human Sgo1 by NEK2A is essential for chromosome congression in mitosis." in: Cell research, Vol. 17, Issue 7, pp. 608-18, (2007) (PubMed).

Thein, Kleylein-Sohn, Nigg, Gruneberg: "Astrin is required for the maintenance of sister chromatid cohesion and centrosome integrity." in: The Journal of cell biology, Vol. 178, Issue 3, pp. 345-54, (2007) (PubMed).

Aliases for Shugoshin 抗体

shugoshin 1 (Sgo1) 抗体
shugoshin centromeric cohesion 1 (sgo1) 抗体
shugoshin 1 L homeolog (sgo1.L) 抗体
shugoshin 1 (SGO1) 抗体
3300001M08Rik 抗体
C81037 抗体
NY-BR-85 抗体
SGO 抗体
sgo1 抗体
Sgo1 抗体
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