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SGOL2 抗体

(Shugoshin-Like 2 (SGOL2))
Cooperates with PPP2CA to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I. Has a crucial role in protecting REC8 at centromeres from cleavage by separase. During meiosis, protects centromeric cohesion complexes until metaphase II/anaphase II transition, preventing premature release of meiosis-specific REC8 cohesin complexes from anaphase I centromeres. Is thus essential for an accurate gametogenesis. May act by targeting PPP2CA to centromeres, thus leading to cohesin dephosphorylation (By similarity). Essential for recruiting KIF2C to the inner centromere and for correcting defective kinetochore attachments.

14 results

SGOL2 适用: 人 WB 宿主: 兔 Polyclonal RB42663 unconjugated
Pubmed 5 references
产品编号 ABIN1881800
 
SGOL2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7188086
 
SGOL2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6287322
 
SGOL2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7452040
 
SGOL2 适用: 人 IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7452431
 
SGOL2 适用: 人, 猴 IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1934414
 
SGOL2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal HRP
产品编号 ABIN1934421
 
SGOL2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2571047
 
SGOL2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal Biotin
产品编号 ABIN1934418
 
SGOL2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal FITC
产品编号 ABIN1934419
 
SGOL2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal PE
产品编号 ABIN1934420
 
SGOL2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal APC
产品编号 ABIN1934417
 
SGOL2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1535371
 
SGOL2 适用: 人 WB, ELISA, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7602258
 
  • 类型 Primary
    • Primary
  • 应用范围
    • ELISA
    • Western Blotting (WB)
    • Immunoprecipitation (IP)
    • Immunohistochemistry (IHC)
    • Flow Cytometry (FACS)
    • Immunocytochemistry (ICC)
    • Immunofluorescence (IF)
    • Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 适用
    • Human
    • Monkey
  • 论文引用
  • 图像
  • Preservative free only
  • 抗体来源
    • Rabbit
  • 克隆形成能力
    • Polyclonal
  • 克隆
    • RB42663
  • 抗原表位
    • AA 391-419
    • AA 175-225
    • Internal Region
    • AA 650-730
    • AA 660-1011
    • AA 681-730
    • AA 750-800
  • 标记
    • 非结合性
    • APC
    • Biotin
    • FITC
    • HRP
    • PE
  • 抗体亚型
    • IgG
    • Ig Fraction
  • Format
    • Liquid
    • Lyophilized
  • Supplier
    • antibodies-online
    • Abcepta
    • Assay Biotechnology Company, Inc.
    • Boster Bio

Latest Publications for our SGOL2 抗体

Gantchev, Martínez Villarreal, Xie, Lefrançois, Gunn, Netchiporouk, Sasseville, Litvinov: "The Ectopic Expression of Meiosis Regulatory Genes in Cutaneous T-Cell Lymphomas (CTCL)." in: Frontiers in oncology, Vol. 9, pp. 429, (2019) (PubMed).

Deeraksa, Pan, Sha, Liu, Eissa, Lin, Yu-Lee: "Plk1 is upregulated in androgen-insensitive prostate cancer cells and its inhibition leads to necroptosis." in: Oncogene, Vol. 32, Issue 24, pp. 2973-83, (2013) (PubMed).

Lindsey, Byrnes, Eller, Rosa, Dabas, Escandon, Grichnik: "Potential role of meiosis proteins in melanoma chromosomal instability." in: Journal of skin cancer, Vol. 2013, pp. 190109, (2013) (PubMed).

Tanno, Kitajima, Honda, Ando, Ishiguro, Watanabe: "Phosphorylation of mammalian Sgo2 by Aurora B recruits PP2A and MCAK to centromeres." in: Genes & development, Vol. 24, Issue 19, pp. 2169-79, (2010) (PubMed).

Ross, Katzov-Eckert, Dubé, Brooks, Rassekh, Barhdadi, Feroz-Zada, Visscher, Brown, Rieder, Rogers, Phillips, Carleton, Hayden: "Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy." in: Nature genetics, Vol. 41, Issue 12, pp. 1345-9, (2009) (PubMed).

Lee, Kitajima, Tanno, Yoshida, Morita, Miyano, Miyake, Watanabe: "Unified mode of centromeric protection by shugoshin in mammalian oocytes and somatic cells." in: Nature cell biology, Vol. 10, Issue 1, pp. 42-52, (2008) (PubMed).

Huang, Feng, Famulski, Rattner, Liu, Kao, Muschel, Chan, Yen: "Tripin/hSgo2 recruits MCAK to the inner centromere to correct defective kinetochore attachments." in: The Journal of cell biology, Vol. 177, Issue 3, pp. 413-24, (2007) (PubMed).

Kitajima, Sakuno, Ishiguro, Iemura, Natsume, Kawashima, Watanabe: "Shugoshin collaborates with protein phosphatase 2A to protect cohesin." in: Nature, Vol. 441, Issue 7089, pp. 46-52, (2006) (PubMed).

Aliases for SGOL2 抗体

shugoshin 2 (SGO2) 抗体
shugoshin 2A (Sgo2a) 抗体
1110007N04Rik 抗体
4932411A20Rik 抗体
5730576N04Rik 抗体
AU018846 抗体
AV008062 抗体
D1Ertd8e 抗体
SGO2 抗体
TRIPIN 抗体
Tripin 抗体
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