SGOL2 抗体 (AA 681-730)
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北京 101111
Quick Overview for SGOL2 抗体 (AA 681-730) (ABIN1535371)
抗原
See all SGOL2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 681-730
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原理
- Sgo2 Antibody
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特异性
- Sgo2 Polyclonal Antibody detects endogenous levels of Sgo2 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human SGOL2. AA range:681-730
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亚型
- IgG
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应用备注
- IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- SGOL2 (Shugoshin-Like 2 (SGOL2))
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别名
- SGOL2
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背景
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Synonyms: SGOL2, Shugoshin-like 2, Shugoshin-2, Sgo2, Tripin
Background: function:During meiosis, protects centromeric cohesion complexes until metaphase II/anaphase II transition, preventing premature release of meiosis-specific REC8 cohesin complexes from anaphase I centromeres. Is thus essential for an accurate gametogenesis (By similarity). May act by targeting PPP2CA to centromeres, thus leading to cohesin dephosphorylation.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the shugoshin family.,subcellular location:In Hela cells, localizes at centromeres throughout prophase until metaphase and disappears at anaphase.,subunit:Directly interacts with PPP2CA.,
Gene Name: SGOL2
Protein Name: Shugoshin-like 2
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分子量
- 144 kDa
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基因ID
- 151246
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OMIM
- 612425
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UniProt
- Q562F6
抗原
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