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SGOL2 抗体

(Shugoshin-Like 2 (SGOL2))
Cooperates with PPP2CA to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I. Has a crucial role in protecting REC8 at centromeres from cleavage by separase. During meiosis, protects centromeric cohesion complexes until metaphase II/anaphase II transition, preventing premature release of meiosis-specific REC8 cohesin complexes from anaphase I centromeres. Is thus essential for an accurate gametogenesis. May act by targeting PPP2CA to centromeres, thus leading to cohesin dephosphorylation (By similarity). Essential for recruiting KIF2C to the inner centromere and for correcting defective kinetochore attachments.
SGOL2 抗体 SGOL2 抗体 SGOL2 抗体 (ABIN5587828)

SGOL2 适用: 人 IHC (p), IF 宿主: 兔 Polyclonal unconjugated

SGOL2 抗体  (AA 391-419) SGOL2 抗体  (AA 391-419) SGOL2 抗体 (AA 391-419) (ABIN1881800)

SGOL2 适用: 人 WB 宿主: 兔 Polyclonal RB42663 unconjugated

SGOL2 抗体 (Internal Region) (ABIN7188086)

SGOL2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated

SGOL2 抗体 by 适用

Find SGOL2 抗体 for a variety of species such as anti-Human SGOL2, anti-Monkey SGOL2. The species listed below are among those available. Click on a link to go to the corresponding products.

SGOL2 抗体 by 应用范围

Find SGOL2 抗体 validated for a specific application such as ELISA, WB, IP, IHC. Some of the available applications are listed below. Click on a link to go to the corresponding products.

SGOL2 抗体 by 抗体来源

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SGOL2 抗体 by 抗原表位

Find SGOL2 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

SGOL2 抗体 by 克隆形成能力

Find available monoclonal or polyclonal SGOL2 抗体. Click on a link to go to the corresponding products.

SGOL2 抗体 by 克隆

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SGOL2 抗体 by 标记

Find SGOL2 抗体 with a specific conjugate such as APC, Alkaline Phosphatase (AP), Biotin. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular SGOL2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application IHC (p), IF
Validations
  • (2)
Cat. No. ABIN5587828
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (5)
  • (1)
Cat. No. ABIN1881800
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
Cat. No. ABIN7188086
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC (p)
Validations
Cat. No. ABIN6287322
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application IP
Validations
Cat. No. ABIN7452431
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
Cat. No. ABIN7452040
Quantity 20 μg
Datasheet Datasheet
Reactivity Human, Monkey
Application IP
Validations
Cat. No. ABIN1934414
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
Cat. No. ABIN1934418
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
Cat. No. ABIN1934416
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
Cat. No. ABIN1934417
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
Cat. No. ABIN2571047
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
Cat. No. ABIN1934421
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
Cat. No. ABIN1934419
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
Cat. No. ABIN1934420
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (1)
Cat. No. ABIN1535371
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our SGOL2 抗体

Gantchev, Martínez Villarreal, Xie, Lefrançois, Gunn, Netchiporouk, Sasseville, Litvinov: "The Ectopic Expression of Meiosis Regulatory Genes in Cutaneous T-Cell Lymphomas (CTCL)." in: Frontiers in oncology, Vol. 9, pp. 429, (2019) (PubMed).

Deeraksa, Pan, Sha, Liu, Eissa, Lin, Yu-Lee: "Plk1 is upregulated in androgen-insensitive prostate cancer cells and its inhibition leads to necroptosis." in: Oncogene, Vol. 32, Issue 24, pp. 2973-83, (2013) (PubMed).

Lindsey, Byrnes, Eller, Rosa, Dabas, Escandon, Grichnik: "Potential role of meiosis proteins in melanoma chromosomal instability." in: Journal of skin cancer, Vol. 2013, pp. 190109, (2013) (PubMed).

Tanno, Kitajima, Honda, Ando, Ishiguro, Watanabe: "Phosphorylation of mammalian Sgo2 by Aurora B recruits PP2A and MCAK to centromeres." in: Genes & development, Vol. 24, Issue 19, pp. 2169-79, (2010) (PubMed).

Ross, Katzov-Eckert, Dubé, Brooks, Rassekh, Barhdadi, Feroz-Zada, Visscher, Brown, Rieder, Rogers, Phillips, Carleton, Hayden: "Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy." in: Nature genetics, Vol. 41, Issue 12, pp. 1345-9, (2009) (PubMed).

Lee, Kitajima, Tanno, Yoshida, Morita, Miyano, Miyake, Watanabe: "Unified mode of centromeric protection by shugoshin in mammalian oocytes and somatic cells." in: Nature cell biology, Vol. 10, Issue 1, pp. 42-52, (2008) (PubMed).

Huang, Feng, Famulski, Rattner, Liu, Kao, Muschel, Chan, Yen: "Tripin/hSgo2 recruits MCAK to the inner centromere to correct defective kinetochore attachments." in: The Journal of cell biology, Vol. 177, Issue 3, pp. 413-24, (2007) (PubMed).

Kitajima, Sakuno, Ishiguro, Iemura, Natsume, Kawashima, Watanabe: "Shugoshin collaborates with protein phosphatase 2A to protect cohesin." in: Nature, Vol. 441, Issue 7089, pp. 46-52, (2006) (PubMed).

Aliases for SGOL2 抗体

shugoshin 2 (SGO2) 抗体
shugoshin 2A (Sgo2a) 抗体
1110007N04Rik 抗体
4932411A20Rik 抗体
5730576N04Rik 抗体
AU018846 抗体
AV008062 抗体
D1Ertd8e 抗体
SGO2 抗体
TRIPIN 抗体
Tripin 抗体
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