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|抗原||Cholinergic Receptor, Nicotinic, alpha 10 (CHRNA10) 抗体|
|适用||人, 小鼠, 大鼠 其他选择|
|标记||Alexa Fluor 350 其他选择|
Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
|Supplier||Log in to see|
产品细节目标详细情况 使用细节 贮存及处理 图像
|纯化方法||Purified by Protein A.|
|免疫原||KLH conjugated synthetic peptide derived from human CHRNA10|
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|别名||Chrna10 (CHRNA10 Antibody 摘要)|
Members of the ligand-gated ion channel receptor family are characterized by their fast transmitting response to neurotransmitters. Two important members of this family are the nicotinic acetylcholine and glutamate receptors, both of which are composed of five homologous subunits forming a transmembrane aqueous pore. These transmembrane receptors change conformation in response to their cognate neurotransmitter. Nicotinic acetylcholine receptors (AChRs) are found at the postsynaptic membrane of the neuromuscular junction and bind acetylcholine molecules, allowing ions to move through the pore. Glutamate receptors are found in the postsynaptic membrane of cells in the central nervous system. The activity that is generated at the synapse by the binding of acetylcholine is terminated by acetylcholinesterase, an enzyme that rapidly hydrolyzes acetylcholine. ACh Ralpha 10, also known as CHRNA10, is a 450 amino acid multi-pass membrane protein expressed in inner-ear tissue, tonsil, immortalized B-cells, cultured T-cells and peripheral blood lymphocytes. AChR alpha 10 forms a hetero-oligomeric channels in conjunction with AChR alpha 9 and is considered an ionotropic receptor with a probable role in the modulation of auditory stimuli.
Subcellular location: Extracellular
Synonyms: Acetylcholine receptor, neuronal nicotinic, alpha-10 subunit, ACH10_HUMAN, Alpha 10 nAChR, Cholinergic receptor nicotinic alpha 10, Cholinergic receptor, neuronal nicotinic, alpha polypeptide 10, Cholinergic receptor, nicotinic, alpha polypeptide 10, CHRNA 10, CHRNA10, NACHR alpha 10, NACHR alpha-10, NACHRA10, Neuronal acetylcholine receptor protein subunit alpha 10, Neuronal acetylcholine receptor subunit alpha-10, Nicotinic acetylcholine receptor subunit alpha 10, Nicotinic acetylcholine receptor subunit alpha-10.
|途径||Sensory Perception of Sound, Synaptic Membrane|
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贮存及处理产品细节 目标详细情况 使用细节 图像 回页首
|缓冲液||Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.|
|注意事项||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.|
|储存方法||Store at 4°C|