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Axin 蛋白

(Axin 1 (AXIN1))
This gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein interacts with adenomatosis polyposis coli, catenin beta-1, glycogen synthase kinase 3 beta, protein phosphate 2, and itself. This protein functions as a negative regulator of the wingless-type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. The crystal structure of a portion of this protein, alone and in a complex with other proteins, has been resolved. Mutations in this gene have been associated with hepatocellular carcinoma, hepatoblastomas, ovarian endometriod adenocarcinomas, and medullablastomas. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Dec 2010].
Axin Protein (AA 540-768) (His tag) Axin Protein (AA 540-768) (His tag) Axin Protein (AA 540-768) (His tag) (ABIN7121954)

AXIN1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA

Axin Protein (AA 643-740) (GST tag) Axin Protein (AA 643-740) (GST tag) Axin Protein (AA 643-740) (GST tag) (ABIN1346237)

AXIN1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP

Axin Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) Axin Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) Axin Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) (ABIN2715088)

AXIN1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD

Axin 蛋白 by Origin

Find Axin 蛋白 for a variety of species such as anti-Human Axin, anti-Mouse Axin, anti-Rat Axin. The species listed below are among those available. Click on a link to go to the corresponding products.

Axin 蛋白 by Source

Here you will find Axin 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

Axin 蛋白 by 蛋白类型

Here you can find Axin 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

Axin 蛋白 by 应用范围

Find Axin 蛋白 validated for a specific application such as WB, SDS, ELISA, Imm. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular Axin 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7121954
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1346237
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
  • (1)
Cat. No. ABIN2715088
Quantity 20 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7405157
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7406062
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7405900
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3089641
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3131624
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3008424
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our Axin 蛋白

Cha, Cho, Lee, Lee, Jeong, Moon, Yun, Yang, Choi, Yoon, Kim, Kim, Kaduwal, Lee, Min, Kim, Han, Choi: "Small-molecule binding of the axin RGS domain promotes β-catenin and Ras degradation." in: Nature chemical biology, Vol. 12, Issue 8, pp. 593-600, (2016) (PubMed).

Aliases for Axin 蛋白

axin 1 (AXIN1) 蛋白
axin 1 S homeolog (axin1.S) 蛋白
axin 1 L homeolog (axin1.L) 蛋白
axin 1 (Axin1) 蛋白
axin 1 (axin1) 蛋白
AI316800 蛋白
axin 蛋白
AXIN 蛋白
Axin 蛋白
AXIN1 蛋白
AXIN1-RGS 蛋白
Fu 蛋白
fused 蛋白
Kb 蛋白
Ki 蛋白
kinky 蛋白
knobbly 蛋白
LOC100226467 蛋白
PPP1R49 蛋白
wu:fi22e03 蛋白
wu:fj14c08 蛋白
wu:fk11b03 蛋白
xAxin 蛋白
zgc:109872 蛋白
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