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- 抗原 See all IgG4 products
- IgG4
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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应用范围
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- Supernatant
- 克隆位点
- MRQ-44
- 亚型
- IgG1
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 注意事项
- Monoclonal antibodies should not be stored at a temperature below -25 °C due to the aggregation effect of the protein.
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- 抗原
- IgG4
- 别名
- Immunoglobulin G4 (IgG4) (IgG4 产品)
- 物质类
- Antibody
- 背景
- IgG4-related sclerosing disease has been recognized as a systemic disease entity characterized by an elevated serum IgG4 level, sclerosing fibrosis and diffuse lymphoplasmacytic infiltration with the presence of many IgG4-positive plasma cells. As these patients tend to respond favorably to steroid treatment, it is important to recognize this entity and differentiate it from such mimics as lymphoma. Clinical manifestations are apparent in the pancreas, bile duct, gallbladder, lacrimal gland, salivary gland, retroperitoneum, kidney, lung, breast, thyroid, and prostate. Immunohistochemical analyses in the case of IgG4-related sclerosing disease not only exhibits significantly more IgG4-positive plasma cells in affected tissues but also significantly higher IgG4/ IgG ratios (typically > 30 % ).Synonyms: Human Immunoglobulin G4
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