兔 anti-人 IgG (Heavy & Light Chain) Antibody
IP, ID
Polyclonal
unconjugated
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- 抗原 See all IgG products
- IgG
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抗原表位
- Heavy & Light Chain
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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应用范围
- Immunoprecipitation (IP), Immunodiffusion (ID)
- 产品特性
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The antiserum of individual host animals was monitored for titre and specificity before pooling into uniform high titre lots.
Against NHS: Single band at all dilutions up to 1/1024.
Against NMS: No bands at a dilution of 1/4.
Against Human IgG (5 mg/mL): Lot 0128 produced a single band homogeneous with a single band from NHS dilutions of 1/4 and 1/8. - 纯化方法
- Serum
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Store the antibody (in aliquots) at -20 °C.
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- 抗原
- IgG
- Abstract
- IgG 产品
- 物质类
- Antibody
- 背景
- IgG is a monomeric immunoglobulin, built of two heavy chains gamma and two light chains. Each molecule has two antigen binding sites. This is the most abundant immunoglobulin and is approximately equally distributed in blood and in tissue liquids, constituting 75 % of serum immunoglobulins in humans. This is the only isotype that can pass through the human placenta, thereby providing protection to the fetus in its first weeks of life before its own immune system has developed. It can bind to many kinds of pathogens, for example viruses, bacteria, and fungi, and protects the body against them by complement activation (classic pathway), opsonization for phagocytosis and neutralisation of their toxins. There are 4 subclasses: IgG1 (66 %), IgG2 (23 %), IgG3 (7 %) and IgG4 (4 %).Synonyms: Human Immunoglobulin G
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