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SETD8 抗体

(SET Domain Containing (Lysine Methyltransferase) 8 (SETD8))
Protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins. Specifically monomethylates 'Lys-20' of histone H4 (H4K20me1). H4K20me1 is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes. Required for cell proliferation, probably by contributing to the maintenance of proper higher order structure of DNA during mitosis. Involved in chromosome condensation and proper cytokinesis. Nucleosomes are preferred as substrate compared to free histones. Mediates monomethylation of p53/TP53 at 'Lys-382', leading to repress p53/TP53-target genes (By similarity).
SETD8 抗体  (N-Term) SETD8 抗体  (N-Term) SETD8 抗体 (N-Term) (ABIN3032551)

SETD8 适用: 人, 小鼠 IF, IHC, ELISA, WB 宿主: 小鼠 Monoclonal 43AT551-86 unconjugated

SETD8 抗体  (N-Term) SETD8 抗体  (N-Term) SETD8 抗体 (N-Term) (ABIN387779)

SETD8 适用: 人 IF, IHC (p), WB 宿主: 小鼠 Monoclonal 43AT551-86 unconjugated

SETD8 抗体  (AA 220-249) SETD8 抗体  (AA 220-249) SETD8 抗体 (AA 220-249) (ABIN390472)

SETD8 适用: 人 FACS, IHC (p), WB 宿主: 兔 Polyclonal RB18964 unconjugated

SETD8 抗体 by 适用

Find SETD8 抗体 for a variety of species such as anti-Human SETD8, anti-Mouse SETD8, anti-Rat SETD8. The species listed below are among those available. Click on a link to go to the corresponding products.

SETD8 抗体 by 应用范围

Find SETD8 抗体 validated for a specific application such as WB, ELISA, IHC, IF. Some of the available applications are listed below. Click on a link to go to the corresponding products.

SETD8 抗体 by 抗体来源

Find SETD8 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

SETD8 抗体 by 抗原表位

Find SETD8 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

SETD8 抗体 by 克隆形成能力

Find available monoclonal or polyclonal SETD8 抗体. Click on a link to go to the corresponding products.

SETD8 抗体 by 克隆

Find SETD8 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

SETD8 抗体 by 标记

Find SETD8 抗体 with a specific conjugate such as FITC, APC, Alkaline Phosphatase (AP). The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular SETD8 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application IF, IHC, ELISA, WB
Validations
  • (5)
Cat. No. ABIN3032551
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application IF, IHC (p), WB
Validations
  • (1)
  • (3)
Cat. No. ABIN387779
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application FACS, IHC (p), WB
Validations
  • (3)
Cat. No. ABIN390472
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application IHC (p), WB
Validations
  • (2)
Cat. No. ABIN387992
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application IF, WB
Validations
  • (2)
Cat. No. ABIN6147653
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Rat
Application IC, IF, WB
Validations
  • (2)
Cat. No. ABIN7307000
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application EIA, IHC (p), WB
Validations
  • (2)
Cat. No. ABIN356687
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (1)
Cat. No. ABIN7160766
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB
Validations
  • (1)
Cat. No. ABIN387780
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN387993
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN7261217
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6972699
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IF
Validations
  • (1)
Cat. No. ABIN7263309
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application ICC, IHC (p), ELISA, WB
Validations
  • (1)
Cat. No. ABIN5693706
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application EIA, WB
Validations
  • (1)
Cat. No. ABIN356688
Quantity 0.4 mL
Datasheet Datasheet

Latest Publications for our SETD8 抗体

Zhang, Bruice: "Product specificity and mechanism of protein lysine methyltransferases: insights from the histone lysine methyltransferase SET8." in: Biochemistry, Vol. 47, Issue 25, pp. 6671-7, (2010) (PubMed).

Frye, Fisher, Watt: "Epidermal stem cells are defined by global histone modifications that are altered by Myc-induced differentiation." in: PLoS ONE, Vol. 2, Issue 8, pp. e763, (2010) (PubMed).

Song, Zheng, Liu, Wei, Dai, Zhang, Calin, Hao, Wei, Zhang, Chen: "An miR-502-binding site single-nucleotide polymorphism in the 3'-untranslated region of the SET8 gene is associated with early age of breast cancer onset." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 15, Issue 19, pp. 6292-300, (2009) (PubMed).

Houston, McManus, Adams, Sims, Carpenter, Hendzel, Rice: "Catalytic function of the PR-Set7 histone H4 lysine 20 monomethyltransferase is essential for mitotic entry and genomic stability." in: The Journal of biological chemistry, Vol. 283, Issue 28, pp. 19478-88, (2008) (PubMed).

Nishioka, Rice, Sarma, Erdjument-Bromage, Werner, Wang, Chuikov, Valenzuela, Tempst, Steward, Lis, Allis, Reinberg: "PR-Set7 is a nucleosome-specific methyltransferase that modifies lysine 20 of histone H4 and is associated with silent chromatin." in: Molecular cell, Vol. 9, Issue 6, pp. 1201-13, (2002) (PubMed).

Fang, Feng, Ketel, Wang, Cao, Xia, Erdjument-Bromage, Tempst, Simon, Zhang: "Purification and functional characterization of SET8, a nucleosomal histone H4-lysine 20-specific methyltransferase." in: Current biology : CB, Vol. 12, Issue 13, pp. 1086-99, (2002) (PubMed).

Aliases for SETD8 抗体

lysine methyltransferase 5A (KMT5A) 抗体
lysine methyltransferase 5A (Kmt5a) 抗体
lysine methyltransferase 5Ab (kmt5ab) 抗体
lysine methyltransferase 5A S homeolog (kmt5a.S) 抗体
2410195B05Rik 抗体
AA617402 抗体
AW536475 抗体
KMT5A 抗体
kmt5a 抗体
kmt5a-a 抗体
PR-Set7 抗体
PR-SET7 抗体
Pr-set7 抗体
RGD1305893 抗体
SET07 抗体
SET8 抗体
Setd8 抗体
setd8 抗体
setd8-a 抗体
setd8b 抗体
wu:fc23f12 抗体
zgc:171649 抗体
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