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Septin 9 产品

(Septin 9 (SEPT9))

Categories

This gene is a member of the septin family involved in cytokinesis and cell cycle control. This gene is a candidate for the ovarian tumor suppressor gene. Mutations in this gene cause hereditary neuralgic amyotrophy, also known as neuritis with brachial predilection. A chromosomal translocation involving this gene on chromosome 17 and the MLL gene on chromosome 11 results in acute myelomonocytic leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Mar 2009].

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Featured Septin 9 Categories

Septin 9 抗体

High quality antibodies with extensive validation data.

Septin 9 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

Septin 9 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Septin 9 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC (p), FACS
Validations
  • (2)
  • (6)
Cat. No. ABIN390155
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
  • (2)
Cat. No. ABIN564709
Quantity 50 μL
Datasheet Datasheet
Reactivity Chicken, Guinea Pig, Hamster, Human, Monkey, Mouse, Rat, Zebrafish (Danio rerio)
Application WB, IHC, IHC (p)
Validations
  • (3)
Cat. No. ABIN6749752
Quantity 100 μL
Datasheet Datasheet

Recommended Septin 9 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970103
Quantity 96 tests
Datasheet Datasheet

Recommended Septin 9 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7125030
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1319565
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1319561
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our Septin 9 Products

Tóth, Wasserkort, Sipos, Kalmár, Wichmann, Leiszter, Valcz, Juhász, Miheller, Patai, Tulassay, Molnár: "Detection of methylated septin 9 in tissue and plasma of colorectal patients with neoplasia and the relationship to the amount of circulating cell-free DNA." in: PLoS ONE, Vol. 9, Issue 12, pp. e115415, (2014) (PubMed).

Wasserkort, Kalmar, Valcz, Spisak, Krispin, Toth, Tulassay, Sledziewski, Molnar: "Aberrant septin 9 DNA methylation in colorectal cancer is restricted to a single CpG island." in: BMC cancer, Vol. 13, pp. 398, (2013) (PubMed).

Tóth, Galamb, Spisák, Wichmann, Sipos, Valcz, Leiszter, Molnár, Tulassay: "The influence of methylated septin 9 gene on RNA and protein level in colorectal cancer." in: Pathology oncology research : POR, Vol. 17, Issue 3, pp. 503-9, (2011) (PubMed).

Amir, Golan, Mabjeesh: "Targeted knockdown of SEPT9_v1 inhibits tumor growth and angiogenesis of human prostate cancer cells concomitant with disruption of hypoxia-inducible factor-1 pathway." in: Molecular cancer research : MCR, Vol. 8, Issue 5, pp. 643-52, (2010) (PubMed).

Bennett, Romigh, Eng: "Disruption of transforming growth factor-beta signaling by five frequently methylated genes leads to head and neck squamous cell carcinoma pathogenesis." in: Cancer research, Vol. 69, Issue 24, pp. 9301-5, (2009) (PubMed).

Sudo, Ito, Iwamoto, Morishita, Asano, Nagata: "SEPT9 sequence alternations causing hereditary neuralgic amyotrophy are associated with altered interactions with SEPT4/SEPT11 and resistance to Rho/Rhotekin-signaling." in: Human mutation, Vol. 28, Issue 10, pp. 1005-13, (2007) (PubMed).

McIlhatton, Burrows, Donaghy, Chanduloy, Johnston, Russell: "Genomic organization, complex splicing pattern and expression of a human septin gene on chromosome 17q25.3." in: Oncogene, Vol. 20, Issue 41, pp. 5930-9, (2001) (PubMed).

Russell, McIlhatton, Burrows, Donaghy, Chanduloy, Petty, Kalikin, Church, McIlroy, Harkin, Keilty, Cranston, Weissenbach, Hickey, Johnston: "Isolation and mapping of a human septin gene to a region on chromosome 17q, commonly deleted in sporadic epithelial ovarian tumors." in: Cancer research, Vol. 60, Issue 17, pp. 4729-34, (2000) (PubMed).

Synonyms and alternative names related to Septin 9

septin 9 (SEPT9), septin 9 (sept9), septin-9 (LOC100605286), septin 9 S homeolog (sept9.S), septin 9 (Sept9), septin 9a (sept9a), af17q25, AF17q25, cb999, Eseptin, fb02h06, msf, MSF, Msf, msf1, MSF1, napb, NAPB, pnutl4, PNUTL4, SEPT9, sept9, septd1, SeptD1, septin-9, sint1, SINT1, Sint1, Slpa, wu:fb02h06

Protein level used designations for Septin 9

  • septin 9
  • septin-9-like
  • septin-9
  • MLL septin-like fusion protein MSF-A
  • Ov/Br septin
  • ovarian/breast septin
  • septin D1
  • MLL septin-like fusion
  • SL3-3 integration site 1 protein
  • E-septin
  • SLP
  • eighth septin
  • septin-like protein
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