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Septin 9 抗体 (C-Term)

SEPT9 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB1931 unconjugated
产品编号 ABIN390155
发货至: 中国
  • 抗原 See all Septin 9 (SEPT9) 抗体
    Septin 9 (SEPT9)
    抗原表位
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 57-85, C-Term
    适用
    • 28
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 24
    • 4
    克隆类型
    • 27
    • 1
    多克隆
    标记
    • 21
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Septin 9 antibody is un-conjugated
    应用范围
    • 16
    • 9
    • 7
    • 5
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This SEPT9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 57-85 amino acids from the C-terminal region of human SEPT9.
    克隆位点
    RB1931
    亚型
    Ig Fraction
  • 应用备注
    WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. IHC-P: 1:50~100. FC: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Amir, Golan, Mabjeesh: "Targeted knockdown of SEPT9_v1 inhibits tumor growth and angiogenesis of human prostate cancer cells concomitant with disruption of hypoxia-inducible factor-1 pathway." in: Molecular cancer research : MCR, Vol. 8, Issue 5, pp. 643-52, (2010) (PubMed).

    Bennett, Romigh, Eng: "Disruption of transforming growth factor-beta signaling by five frequently methylated genes leads to head and neck squamous cell carcinoma pathogenesis." in: Cancer research, Vol. 69, Issue 24, pp. 9301-5, (2009) (PubMed).

  • 抗原
    Septin 9 (SEPT9)
    别名
    SEPT9 (SEPT9 产品)
    别名
    SEPT9 antibody, msf antibody, msf1 antibody, napb antibody, sint1 antibody, pnutl4 antibody, septd1 antibody, af17q25 antibody, septin-9 antibody, AF17q25 antibody, MSF antibody, MSF1 antibody, NAPB antibody, PNUTL4 antibody, SINT1 antibody, SeptD1 antibody, Msf antibody, Sint1 antibody, Eseptin antibody, Slpa antibody, cb999 antibody, fb02h06 antibody, sept9 antibody, wu:fb02h06 antibody, septin 9 antibody, septin-9 antibody, septin 9 S homeolog antibody, septin 9a antibody, SEPT9 antibody, sept9 antibody, LOC100605286 antibody, sept9.S antibody, Sept9 antibody, sept9a antibody
    背景
    The maf oncogene was identified by structural analysis of the AS42 avian transforming retrovirus genome. The Maf family is divided into two subclasses, large Mafs (vMaf, cMaf, MafB and Nrl) and small Mafs (MafF, MafK, and MafG). Both subclasses contain leucinezipper motifs, which allow homodimerization as well as heterodimerization with a variety of other bZip transcription factors. Large Mafs also contain an acidic transactivation domain absent in the small Maf proteins. Although they do not possess inherent transactivation activity, small Maf proteins can act as positive regulators of transcription by targeting transcriptionally active dimerization partners to specific DNA regulatory elements. Conversely, small Mafs can act also as negative regulators of transcription by recruiting transcriptional repressors or by forming homodimers that can replace active dimers. Human MafF was isolated in a yeast one-hybrid system from a human myometrium cDNA library. Human MAFF encodes a 164 amino acids proten. Like other small MAFF proteins, it contains an extended leucine zipper structure and lacks an N-terminal transactivating domain. The three small Maf proteins have been implicated in a number of physiological processes, including development, differentiation, haematopoiesis and stress response. Interestingly, these three proteins regulate the stress response via different mechanisms.
    分子量
    65401
    基因ID
    7975
    NCBI登录号
    NP_001106963, NP_001106964, NP_001106965, NP_001106966, NP_001106967, NP_001106968, NP_006631
    UniProt
    Q9UHD8
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