Senataxin 抗体
(Senataxin (SETX))
This gene encodes a protein named for its homology to the Sen1p protein of fungi which has RNA helicase activity encoded by a domain at the C-terminal end of the protein. The protein encoded by this gene contains a DNA/RNA helicase domain at its C-terminal end which suggests that it may be involved in both DNA and RNA processing. Mutations in this gene have been associated with ataxia-ocular apraxia-2 (AOA2) and an autosomal dominant form of juvenile amyotrophic lateral sclerosis (ALS4). [provided by RefSeq, Jul 2008].
Recommended next Filters:
您想试用我们的人工智能搜索吗？
26 results
SETX
适用: 人
WB, IP
宿主: 兔
Monoclonal
BLR050F
unconjugated
Recombinant Antibody
Latest Publications for our Senataxin 抗体
: "Sae2/CtIP prevents R-loop accumulation in eukaryotic cells." in: eLife, Vol. 7, (2019) (PubMed).: "Dual Processing of R-Loops and Topoisomerase I Induces Transcription-Dependent DNA Double-Strand Breaks." in: Cell reports, Vol. 28, Issue 12, pp. 3167-3181.e6, (2019) (PubMed).
: "Senataxin resolves RNA:DNA hybrids forming at DNA double-strand breaks to prevent translocations." in: Nature communications, Vol. 9, Issue 1, pp. 533, (2018) (PubMed).
: "A senataxin-associated exonuclease SAN1 is required for resistance to DNA interstrand cross-links." in: Nature communications, Vol. 9, Issue 1, pp. 2592, (2018) (PubMed).
: "Altered translational repression of an RNA-binding protein, Elav by AOA2-causative Senataxin mutation." in: Synapse (New York, N.Y.), Vol. 71, Issue 5, (2017) (PubMed).
: "Functions of Replication Protein A as a Sensor of R Loops and a Regulator of RNaseH1." in: Molecular cell, Vol. 65, Issue 5, pp. 832-847.e4, (2017) (PubMed).
: "SMN and symmetric arginine dimethylation of RNA polymerase II C-terminal domain control termination." in: Nature, Vol. 529, Issue 7584, pp. 48-53, (2016) (PubMed).
: "A SUMO-dependent interaction between Senataxin and the exosome, disrupted in the neurodegenerative disease AOA2, targets the exosome to sites of transcription-induced DNA damage." in: Genes & development, Vol. 27, Issue 20, pp. 2227-32, (2013) (PubMed).
Aliases for Senataxin 抗体
senataxin (SETX) 抗体senataxin (setx) 抗体
senataxin (Setx) 抗体
A130090N03 抗体
A930037J23Rik 抗体
ALS4 抗体
Als4 抗体
AOA2 抗体
AW060766 抗体
bA479K20.2 抗体
mKIAA0625 抗体
RGD1565575 抗体
SCAR1 抗体
Sen1 抗体
SETX 抗体
wu:fj92h09 抗体
您还需要查找其他产品吗？
You are here:
