SARM1 抗体
(Sterile alpha and TIR Motif Containing 1 (SARM1))
Involved in innate immnune response. Acts as a negative regulator of TICAM1/TRIF-dependent Toll-like receptor signaling by inhibiting induction of TLR3- and TLR4-dependent genes. Specifically blocks TICAM1/TRIF-dependent transcription-factor activation and gene induction, without affecting the MYD88- dependent pathway or non-TLR signaling. Negative regulator of NF- kappa-B and IRF activation (By similarity).
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| SARM1 抗体 (AA 51-724) (FL550) | 人 | 小鼠 Monoclonal |
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| SARM1 抗体 (AA 51-724) (FL650) | 人 | 小鼠 Monoclonal |
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| SARM1 抗体 (AA 51-724) | 人 | 小鼠 Monoclonal |
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| SARM1 抗体 (AA 51-724) (FL594) | 人 | 小鼠 Monoclonal |
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| SARM1 抗体 (AA 51-724) | 人 | 小鼠 Monoclonal |
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| SARM1 抗体 (AA 51-724) (FL490) | 人 | 小鼠 Monoclonal |
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| SARM1 抗体 | 人 | 小鼠 Monoclonal |
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| SARM1 抗体 (Intracellular) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| SARM1 抗体 (Center) | 人, 小鼠 | 兔 Polyclonal |
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| SARM1 抗体 (AA 281-330) | 人, 小鼠 | 兔 Polyclonal |
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| SARM1 抗体 (AA 51-724) | 人 | 小鼠 Monoclonal |
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Primary Antibody
- IHC (Immunohistochemistry: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 1561353
- 标记
- FL550
- 抗体亚型
- IgG2b
- 抗原表位
- AA 51-724
Primary Antibody
- IHC (Immunohistochemistry: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 1561353
- 标记
- FL650
- 抗体亚型
- IgG2b
- 抗原表位
- AA 51-724
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 6174-11
- 标记
- unconjugated
- 抗体亚型
- IgG2b
- 抗原表位
- AA 51-724
Primary Antibody
- IHC (Immunohistochemistry: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 1561353
- 标记
- FL594
- 抗体亚型
- IgG2b
- 抗原表位
- AA 51-724
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- 质量等级
- Carrier-free
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 6174-11
- 标记
- unconjugated
- 抗体亚型
- IgG2b
- 抗原表位
- AA 51-724
Primary Antibody
- IHC (Immunohistochemistry: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 1561353
- 标记
- FL490
- 抗体亚型
- IgG2b
- 抗原表位
- AA 51-724
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 质量等级
- Carrier-free
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 361-376, Intracellular
Primary Antibody
- WB (Western Blotting: 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- Center
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 281-330
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 6174-11
- 标记
- unconjugated
- 抗体亚型
- IgG2b
- 抗原表位
- AA 51-724
Latest Publications for our SARM1 抗体
: "Hm-MyD88 and Hm-SARM: two key regulators of the neuroimmune system and neural repair in the medicinal leech." in: Scientific reports, Vol. 5, pp. 9624, (2015) (PubMed).
: "Activation of TLR3 promotes the degeneration of retinal ganglion cells by upregulating the protein levels of JNK3." in: Investigative ophthalmology & visual science, Vol. 56, Issue 1, pp. 505-14, (2015) (PubMed).
: "SARM1 and TRAF6 bind to and stabilize PINK1 on depolarized mitochondria." in: Molecular biology of the cell, Vol. 24, Issue 18, pp. 2772-84, (2013) (PubMed).
: "Excitotoxicity upregulates SARM1 protein expression and promotes Wallerian-like degeneration of retinal ganglion cells and their axons." in: Investigative ophthalmology & visual science, Vol. 54, Issue 4, pp. 2771-80, (2013) (PubMed).
: "The Toll-IL-1 receptor adaptor family grows to five members." in: Trends in immunology, Vol. 24, Issue 6, pp. 286-90, (2003) (PubMed).
: "Toll-like receptors." in: Annual review of immunology, Vol. 21, pp. 335-76, (2003) (PubMed).
: "Innate immune recognition." in: Annual review of immunology, Vol. 20, pp. 197-216, (2002) (PubMed).
: "Activation of TLR3 promotes the degeneration of retinal ganglion cells by upregulating the protein levels of JNK3." in: Investigative ophthalmology & visual science, Vol. 56, Issue 1, pp. 505-14, (2015) (PubMed).
: "SARM1 and TRAF6 bind to and stabilize PINK1 on depolarized mitochondria." in: Molecular biology of the cell, Vol. 24, Issue 18, pp. 2772-84, (2013) (PubMed).
: "Excitotoxicity upregulates SARM1 protein expression and promotes Wallerian-like degeneration of retinal ganglion cells and their axons." in: Investigative ophthalmology & visual science, Vol. 54, Issue 4, pp. 2771-80, (2013) (PubMed).
: "The Toll-IL-1 receptor adaptor family grows to five members." in: Trends in immunology, Vol. 24, Issue 6, pp. 286-90, (2003) (PubMed).
: "Toll-like receptors." in: Annual review of immunology, Vol. 21, pp. 335-76, (2003) (PubMed).
: "Innate immune recognition." in: Annual review of immunology, Vol. 20, pp. 197-216, (2002) (PubMed).
Aliases for SARM1 抗体
sterile alpha and TIR motif containing 1 (SARM1) 抗体sterile alpha and HEAT/Armadillo motif containing 1 (Sarm1) 抗体
sterile alpha and TIR motif containing 1 (Sarm1) 抗体
sterile alpha and TIR motif containing 1 (sarm1) 抗体
A830091I15Rik 抗体
C78606 抗体
MyD88-5 抗体
MyD885 抗体
SAMD2 抗体
Sarm 抗体
SARM 抗体
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