SARM1 抗体 (AA 281-330)
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北京 101111
Quick Overview for SARM1 抗体 (AA 281-330) (ABIN8124968)
抗原
See all SARM1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 281-330
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原理
- SARM1 Antibody
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特异性
- SARM1 Polyclonal Antibody detects endogenous levels of protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from human protein . at AA range: 281-330
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亚型
- IgG
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anti-Sterile alpha and TIR Motif Containing 1 (SARM1) (AA 340-380) antibody
SARM1 适用: 人 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Sterile alpha and TIR Motif Containing 1 (SARM1) (AA 93-292) antibodySARM1 适用: 人 IHC, IP, IHC (p) 宿主: 小鼠 Monoclonal Sarmy-1 unconjugated
anti-Sterile alpha and TIR Motif Containing 1 (SARM1) (C-Term) antibodySARM1 适用: 人, 小鼠 WB, IHC, ICC, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
anti-Sterile alpha and TIR Motif Containing 1 (SARM1) antibodySARM1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Sterile alpha and TIR Motif Containing 1 (SARM1) (AA 361-376), (Intracellular) antibodySARM1 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sterile alpha and TIR Motif Containing 1 (SARM1) (C-Term) antibodySARM1 适用: 人, 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-2000 ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- SARM1 (Sterile alpha and TIR Motif Containing 1 (SARM1))
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别名
- SARM1
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背景
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Background: caution:Was initially reported to contain ARM repeats (PubMed:11386760). Such repeats are however not predicted by any detection method.,function:Involved in innate immnune response. Acts as a negative regulator of TICAM1/TRIF-dependent Toll-like receptor signaling by inhibiting induction of TLR3- and TLR4-dependent genes. Specifically blocks TICAM1/TRIF-dependent transcription-factor activation and gene induction, without affecting the MYD88-dependent pathway or non-TLR signaling. Negative regulator of NF-kappa-B and IRF activation.,similarity:Contains 1 TIR domain.,similarity:Contains 2 SAM (sterile alpha motif) domains.,subunit:Interacts with TICAM1/TRIF and thereby interferes with TICAM1/TRIF function.,tissue specificity:Predominantly expressed in kidney and liver. Expressed at lower level in placenta.,
Gene Name: SARM1 KIAA0524 SAMD2 SARM
Protein Name: Sterile alpha and TIR motif-containing protein 1 (Sterile alpha and Armadillo repeat protein) (Sterile alpha motif domain-containing protein 2) (SAM domain-containing protein 2) (Tir-1 homolog)
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基因ID
- 23098
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UniProt
- Q6SZW1
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途径
- TLR signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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