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Polyclonal PDZK1IP1 Primary Antibody for WB - ABIN540344
Kojima, Sher-Chen, Green: Circadian control of mRNA polyadenylation dynamics regulates rhythmic protein expression. in Genes & development 2012
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Human Polyclonal PDZK1IP1 Primary Antibody for WB - ABIN152919
Silver, Wang, Vogel: Identification of small PDZK1-associated protein, DD96/MAP17, as a regulator of PDZK1 and plasma high density lipoprotein levels. in The Journal of biological chemistry 2003
MAP17 overexpression activates Notch (显示 NOTCH1 抗体) pathway by sequestering NUMB (显示 NUMB 抗体). High levels of MAP17 correlated with tumorsphere formation and Notch (显示 NOTCH1 抗体) and Stem gene transcription. Its direct modification causes direct alteration of tumorsphere number and Notch (显示 NOTCH1 抗体) and Stem pathway transcription
We found that the levels of MAP17 were related to clinical features and poor survival in a cohort of 69 patients with different sarcoma types and suggest that MAP17 is a new biomarker to predict the efficacy of bortezomib as a new therapy for sarcomas.
SGLT2 (显示 SLC5A2 抗体)/MAP17 functions as a low-affinity Na(+)-glucose cotransporter (显示 SLC5A1 抗体) in the kidney.
Differential gene expression analysis demonstrated significant upregulation of PDZK1IP1, EEF1A2 (显示 EEF1A2 抗体) and RPL41 (显示 RPL41 抗体) (ENSG00000279483) genes in the intrahepatic cholangiocarcinoma samples when compared with the matched paratumor samples.
Data show that bortezomib induces a prosurvival response through cytoprotective autophagy and nuclear factor kappa B (NFkappaB (显示 NFKB1 抗体)) nuclear translocation, which is repressed by high levels of membrane-associated protein 17 (MAP17).
In this study we found that the levels of MAP17 were related to clinical findings and survival in a cohort of 58 patients with larynx cancer
Results suggest that the use of MAP17 and SGLT1 (显示 SLC5A1 抗体) markers may identify patients who are likely to exhibit a better response to treatments that boost oxidative stress in other cancer types.
MAP17 is overexpressed in late-stage breast tumors, in which oncogenic activity relies on p38 (显示 CRK 抗体) insensitivity to induce intracellular ROS (显示 ROS1 抗体).
The Th cell cytokine-induced up-regulation of MAP17 expression may be linked to the down-regulation of filaggrin (显示 FLG 抗体) in normal epidermal keratinocytes, which may be associated with abnormal epidermal differentiation observed in the dermatological diseases.
Large scale genetic screening identifies MAP17 as protein bypassing TNF-alpha (显示 TNF 抗体)-induced growth arrest.
membrane associated protein 17 may be an endogenous regulator of cellular PDZ domain containing 1(PDZK1 (显示 PDZK1 抗体)) levels by regulating PDZK1 (显示 PDZK1 抗体) turnover
MAP17 1) interacts with PDZK1 (显示 PDZK1 抗体) only, 2) associates with the NH2 terminus of NaPi-IIa within the PDZK1 (显示 PDZK1 抗体)/NaPi-IIa/MAP17 complex, and 3) acts as an apical anchoring site for PDZK1 (显示 PDZK1 抗体).
the interaction between MAP17, NHERF3 (显示 PDZK1 抗体)/4, and NaPiIIa in the trans-Golgi network could be an important intermediate or alternate path in the internalization of NaPiIIa
Knockout mice for 3 members of the sodium-hydrogen regulatory factor (NHERF (显示 SLC9A3R1 抗体)) family of PDZ (显示 INADL 抗体) adaptor proteins, NHERF1 (EBP50 (显示 SLC9A3R1 抗体)), NHERF2 (E3KARP (显示 SLC9A3R2 抗体)) and NHERF3 (PDZK1 (显示 PDZK1 抗体)), have helped to show that NHERF1 (显示 SLC9A3R2 抗体) is essential for both normal and mutant CFTR (显示 CFTR 抗体) function [review]
Systematic analysis of Pdzk1ip1 is reported.
XPteg functions as a direct transcriptional target of RA signaling to regulate pronephric tubulogenesis in Xenopus early development
expressed specifically in kidney\; increased expression is detected in renal carcinoma
PDZK1-interacting protein 1
, 17 kDa membrane-associated protein
, PDZK1 interacting protein 1
, epithelial protein up-regulated in carcinoma, membrane associated protein 17
, membrane-associated protein 17
, membrane-associated protein 17 (Map17)
, MAP-like protein
, MAP17-like protein
, membrane-associated protein
, proximal tubules-expressed gene protein
, proximal tubules-expressing