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抗Mouse (Murine) 抗体:
Human Polyclonal ALDH1A2 Primary Antibody for IHC, IHC (p) - ABIN4279209
Kostareli, Holzinger, Bogatyrova, Hielscher, Wichmann, Keck, Lahrmann, Grabe, Flechtenmacher, Schmidt, Seiwert, Dyckhoff, Dietz, Höfler, Pawlita, Benner, Bosch, Plinkert, Plass, Weichenhan, Hess: HPV-related methylation signature predicts survival in oropharyngeal squamous cell carcinomas. in The Journal of clinical investigation 2013
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This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Four transcript variants encoding distinct isoforms have been identified for this gene.
, aldehyde dehydrogenase 1A2
, aldehyde dehydrogenase family 1 member A2
, aldehyde dehydrogenase family 1, subfamily A2
, retinal dehydrogenase 2
, retinal dehydrogenase, type II
, retinaldehyde-specific dehydrogenase type 2
, retinaldehyde dehydrogenase 2
, alcohol dehydrogenase family 1, subfamily A2
, alcohol dehydrogenase family 1, subfamily A7