Use your antibodies-online credentials, if available.
Human Polyclonal MOCOS Primary Antibody for ICC, IF - ABIN4335161
Féron, Gepner, Lacassagne, Stephan, Mesnage, Blanchard, Boulanger, Tardif, Devèze, Rousseau, Suzuki, Izpisua Belmonte, Khrestchatisky, Nivet, Erard-Garcia: Olfactory stem cells reveal MOCOS as a new player in autism spectrum disorders. in Molecular psychiatry 2016
MOCOS sulfurates the molybdenum cofactor of xanthine oxidase (XDH (显示 XDH 抗体)) and aldehyde oxidase 1 (AOX1 (显示 AOX1 抗体)), which is required for their activities.
Two mutations, both in the N-terminal domain of the Human Molybdenum Cofactor Sulfurase (HMCS), were reported in patients with type II xanthinuria.
MOCOS loss of function variant is highly likely to cause the renal syndrome in the affected animals
These data suggest that overexpression of LOS5/ABA3 could improve drought tolerance in transgenic soybean via enhanced abscissic acid accumulation.
Data indicate that overexpression of Arabidopsis molybdenum cofactor sulfurase gene (LOS5) in maize markedly enhanced the expression of ZmAO (显示 MAOB 抗体) and aldehyde oxidase (AO (显示 AOX1 抗体)) activity, leading to abscisic acid (ABA) accumulation and increased drought tolerance.
Identification of persulfide-binding and disulfide-forming cysteine residues in the NifS (显示 NFS1 抗体)-like domain of the molybdenum cofactor sulfurase ABA3.
Overexpression of LOS5 in transgenic tobacco can enhance drought tolerance.
Mutation in Moco-sulfurase causes diminished aldehyde oxidase (显示 AOX1 抗体) and xanthine dehydrogenase (显示 XDH 抗体) activities and loss of efficient chloroplast protein import.
analysis of the NifS (显示 NFS1 抗体)-like domain of ABA3 from Arabidopsis thaliana which has a role in molybdenum cofactor sulfuration
the C-terminal domain of ABA3 might act as a scaffold protein (显示 HOMER1 抗体) where prebound desulfo-molybdenum cofactor is converted into sulfurated cofactor prior to activation of aldehyde oxidase (显示 AOX1 抗体) and xanthine dehydrogenase (显示 XDH 抗体).
MOCOS sulfurates the molybdenum cofactor of xanthine dehydrogenase (XDH\; MIM 607633) and aldehyde oxidase (AOX1\; MIM 602841), which is required for their enzymatic activities (Ichida et al., 2001
, molybdenum cofactor sulfurtransferase
, molybdenum cofactor sulfurase
, protein organdy
, Molybdenum cofactor sulfurase-like