Use your antibodies-online credentials, if available.
抗Mouse (Murine) 抗体:
抗Rat (Rattus) 抗体:
Human Polyclonal ZNF537 Primary Antibody for ICC, IF - ABIN4367363
Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. in Nature methods 2013
strong experimental evidence for a causal relationship between Tshz3 heterozygosity, functional defaults in cortical projection neurons, and autism spectrum disorder
suggest a novel mechanism for transcriptional repression by TSHZ3 in which TSHZ3 and BAF57 (显示 SMARCE1 抗体) cooperate to modulate MyoD (显示 MYOD1 抗体) activity on the Myog (显示 MYOG 抗体) promoter to regulate skeletal muscle differentiation.
Thus, a single gene, Tshz3, controls the development of diverse components of the circuitry required for breathing.
Mice that are null (显示 tshz2 抗体) mutant for the Teashirt3 (Tshz3) gene exhibit congenital pelvi-ureteric junction obstruction with defective smooth muscle differentiation and absent peristalsis in the proximal ureter.
three mouse Tsh genes are functionally equivalent to the Drosophila tsh gene when expressed in developing Drosophila embryos
ureteric smooth muscle cell precursors express the transcription factor teashirt 3 (TSHZ3), and Tshz3-null mutants have congenital hydronephrosis without anatomical obstruction
Gene product expressions of SHH (显示 SHH 抗体), TBX18 (显示 TBX18 抗体) and TSHZ3 are statistically higher in patients with UPJ obstruction, when compared with control group. The explanation may be the reactivation of the processes, which had shown their effects in the embryological period, due to the chronic inflammation and long-term micro-trauma created by the disease
Gli3 (显示 GLI3 抗体) and Teashirt3 might play an important role in the normal development of the ureter.
The dynamic expression of Sox9 (显示 SOX9 抗体) and the interaction between TSHZ3, SOX9 (显示 SOX9 抗体) and MYOCD (显示 MYOCD 抗体) provide a mechanism that regulates the pace the myogenic program in the ureter.
TSHZ3 gene promoter was found to be methylated in all the breast/prostate cancer cell lines and some of the breast cancer clinical specimens while the TSHZ2 (显示 tshz2 抗体) gene promoter was unmethylated except for the MDA-MB-231 breast cancer cell line.
Mutations in TSHZ2 (显示 tshz2 抗体) and TSHZ3 are not a major cause of pelvi-ureteric junction obstruction, at least in Albanian and Macedonian populations.
Transcriptional regulator involved in developmental processes. Function in association with APBB1, SET and HDAC factors as a transcriptional repressor, that inhibits the expression of CASP4. TSHZ3-mediated transcription repression involves the recruitment of histone deacetylases HDAC1 and HDAC2. Associates with chromatin in a region surrounding the CASP4 transcriptional start site(s). Regulates the development of neurons involved in both respiratory rhythm and airflow control. Promotes maintenance of nucleus ambiguus (nA) motoneurons, which govern upper airway function, and establishes a respiratory rhythm generator (RRG) activity compatible with survival at birth. Involved in the differentiation of the proximal uretic smooth muscle cells during developmental processes. Involved in the up- regulation of myocardin, that directs the expression of smooth muscle cells in the proximal ureter (By similarity).
teashirt family zinc finger 3
, zinc finger protein 537
, teashirt 3
, teashirt homolog 3
, teashirt zinc finger family member 3