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Human Polyclonal YBX1 Primary Antibody for IF, WB - ABIN1882002
Osada, Uno, Mineta, Kameoka, Takahashi, Terao: Ancient genome-wide admixture extends beyond the current hybrid zone between Macaca fascicularis and M. mulatta. in Molecular ecology 2010
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Human Polyclonal YBX1 Primary Antibody for ICC, IF - ABIN4366500
Dey, Robitaille, Remke, Maier, Malhotra, Gregorieff, Wrana, Taylor, Angers, Kenney: YB-1 is elevated in medulloblastoma and drives proliferation in Sonic hedgehog-dependent cerebellar granule neuron progenitor cells and medulloblastoma cells. in Oncogene 2016
Human Polyclonal YBX1 Primary Antibody for ICC, IF - ABIN4366502
Stickeler, Fraser, Honig, Chen, Berget, Cooper: The RNA binding protein YB-1 binds A/C-rich exon enhancers and stimulates splicing of the CD44 alternative exon v4. in The EMBO journal 2001
YB-1 regulates miR (显示 MLXIP 抗体)-155 expression via c-Myb (显示 MYB 抗体) in the laryngeal squamous cell carcinoma.Laryngeal squamous cell carcinoma patients with high YB-1 expression showed poor overall survival.
infiltrating CD4 (显示 CD4 抗体) + T cells promoted TGFbeta1 (显示 TGFB1 抗体) expression in both renal cell carcinoma (显示 MOK 抗体) and T cells and regulated renal cell carcinoma (显示 MOK 抗体) cells proliferation via modulating TGFbeta1 (显示 TGFB1 抗体)/YBX1/ HIF2alpha (显示 EPAS1 抗体) signals
structural basis of the interactions between YB-1 and mRNAs carrying the aforementioned motifs
YB-1 silencing sensitized SH-SY5Y cells to cisplatin and promoted the apoptosis induced by cisplatin due to down-regulation of multidrug resistance (MDR) 1 (显示 TBC1D9 抗体) protein via NF-kappaB (显示 NFKB1 抗体) signaling pathway.
YB-1 promoted lung adenocarcinoma growth and progression in vitro and in vivo through directly binding to the MACC1 promoter and enhancing MACC1/c-Met pathway.
Data indicate that YB-1 translocates to the nucleus coordinately with p53 (显示 TP53 抗体) expression and is involved in gemcitabine resistance in bladder cancer suggesting that nuclear expression of YB-1 is important for resistance to chemotherapy including gemcitabine in TP53 (显示 TP53 抗体)-mutated bladder cancer.
Results show that YBX1 expression is regulated by TP53TG1 which binds to YBX1 promoter and prevents its nuclear localization.
Kindlin-2 (显示 FERMT2 抗体) is up-regulated in glioma cells and acts as an oncogene (显示 RAB1A 抗体). It is an independent risk factor for poor prognosis. The Kindlin-2 (显示 FERMT2 抗体)/YB-1/beta-catenin (显示 CTNNB1 抗体) complex promotes EGFR (显示 EGFR 抗体) transcription and contributes to glioma progression. Kindlin-2 (显示 FERMT2 抗体) is a potential diagnostic and prognostic marker in glioma, and inhibition of Kindlin-2 (显示 FERMT2 抗体) may be a novel strategy for glioma treatment.
Results showed that YB-1 promoted hepatocellular carcinoma (HCC (显示 FAM126A 抗体)) cell proliferation, migration and colony formation. Also, YB-1 was found to increased drug resistance in HCC (显示 FAM126A 抗体). These findings suggested that YB-1 was a key factor in HCC (显示 FAM126A 抗体) tumorigenesis and maintained the HCC (显示 FAM126A 抗体) initiating cell population.
Furthermore, use of both indirubin 3'-oxime and actinomycin D in combination increased the anticancer effect on HepG2 cells. Indirubin 3'-oxime is a novel and efficient inhibitor of anticancer agent-induced YB-1 nuclear translocation.
The amounts of YB-1 and YB-1 mRNA in rabbit organs and several cell lines.
results prove direct inhibitory action of YB-1 on its mRNA translation, while the positive effect of PABP (显示 PABPC1 抗体) is realized through displacing YB-1 from the regulatory element
his is the first report showing the increased expression of YB-1 during muscle regeneration after ischemic injury.
YB-1 orchestrates onset and resolution of renal inflammation via IL-10 (显示 IL10 抗体) gene regulation.
Monocytic YB-1 has prominent and distinct roles for cellular feed-forward crosstalk and resolution of inflammatory processes by its ability to regulate cell differentiation and cytokine/chemokine (显示 CCL1 抗体) synthesis.
YB-1 is induced by Shh (显示 SHH 抗体) in CGNPs
this study shows that innate immunity activation by muramyl peptides is mediated via an interaction between YB1 and NOD2 (显示 NOD2 抗体)
In conclusion, TGF-beta (显示 TGFB1 抗体) signaling pathway may influence liver fibrosis by incorporating with YB-1, indicating that YB-1 could be a potential target for therapies against liver fibrosis.
Reduction in the expression of YBX1 and ILF3 controls the expression of pluripotency-related genes in ESCs (显示 NR2E3 抗体), suggesting their roles in further regulation of the pluripotent state of ESCs (显示 NR2E3 抗体).
In the initial stage of myocyte differentiation, transcription of the YB-1 gene was regulated by E2F1 (显示 E2F1 抗体) and Sp1 (显示 SP1 抗体), and was then gradually replaced under the control of both MyoD (显示 MYOD1 抗体) and myogenin (显示 MYOG 抗体).
YB-1 is a novel intracellular target of activated protein C (显示 PROC 抗体) in renal ischemia-reperfusion injury
miR (显示 MLXIP 抗体)-382 inhibits osteosarcoma metastasis and relapse by targeting YB-1 protein.
transcription factor; acts as a regulator of protein tyrosine phosphatase PTP1B expression
B box-binding protein
, CCAAT-binding transcription factor I subunit A
, DNA-binding protein B
, Y-box transcription factor
, Y-box-binding protein 1
, enhancer factor I subunit A
, major histocompatibility complex, class II, Y box-binding protein I
, nuclease sensitive element binding protein 1
, nuclease-sensitive element-binding protein 1
, CCAAT-binding transcription factor 1 subunit A
, DNA binding protein B
, Y box transcription factor
, enhancer factor 1 alpha
, enhancer factor 1 subunit A
, FRG Y
, frg y1
, frog Y-box proteins
, Y-box binding protein 1