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Human Polyclonal YBX1 Primary Antibody for IF, WB - ABIN1882002
Osada, Uno, Mineta, Kameoka, Takahashi, Terao: Ancient genome-wide admixture extends beyond the current hybrid zone between Macaca fascicularis and M. mulatta. in Molecular ecology 2010
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Human Polyclonal YBX1 Primary Antibody for IF (p), IHC (p) - ABIN675683
Wang, Sun, Gu, Li, Zhang, Chi, Hao: shRNA-Mediated Silencing of Y-Box Binding Protein-1 (YB-1) Suppresses Growth of Neuroblastoma Cell SH-SY5Y In Vitro and In Vivo. in PLoS ONE 2015
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Human Polyclonal YBX1 Primary Antibody for ICC, IF - ABIN4366502
Stickeler, Fraser, Honig, Chen, Berget, Cooper: The RNA binding protein YB-1 binds A/C-rich exon enhancers and stimulates splicing of the CD44 alternative exon v4. in The EMBO journal 2001
Human Polyclonal YBX1 Primary Antibody for ICC, IF - ABIN4366500
Dey, Robitaille, Remke, Maier, Malhotra, Gregorieff, Wrana, Taylor, Angers, Kenney: YB-1 is elevated in medulloblastoma and drives proliferation in Sonic hedgehog-dependent cerebellar granule neuron progenitor cells and medulloblastoma cells. in Oncogene 2016
Kindlin-2 (显示 FERMT2 抗体) is up-regulated in glioma cells and acts as an oncogene (显示 RAB1A 抗体). It is an independent risk factor for poor prognosis. The Kindlin-2 (显示 FERMT2 抗体)/YB-1/beta-catenin (显示 CTNNB1 抗体) complex promotes EGFR (显示 EGFR 抗体) transcription and contributes to glioma progression. Kindlin-2 (显示 FERMT2 抗体) is a potential diagnostic and prognostic marker in glioma, and inhibition of Kindlin-2 (显示 FERMT2 抗体) may be a novel strategy for glioma treatment.
Results showed that YB-1 promoted hepatocellular carcinoma (HCC (显示 FAM126A 抗体)) cell proliferation, migration and colony formation. Also, YB-1 was found to increased drug resistance in HCC (显示 FAM126A 抗体). These findings suggested that YB-1 was a key factor in HCC (显示 FAM126A 抗体) tumorigenesis and maintained the HCC (显示 FAM126A 抗体) initiating cell population.
Furthermore, use of both indirubin 3'-oxime and actinomycin D in combination increased the anticancer effect on HepG2 cells. Indirubin 3'-oxime is a novel and efficient inhibitor of anticancer agent-induced YB-1 nuclear translocation.
It would appear that YB-1 could regulate cell invasion and migration via downregulation of its indirect target coronin-1C (显示 CORO1C 抗体). The association between YB-1 and coronin-1C (显示 CORO1C 抗体) offers a novel approach by which metastasis of breast cancer cells could be targeted and abrogated.
Inhibition of YBX1 suppressed lung cancer growth partly via the CDC25a pathway and high expression of YBX1/CDC25a predicts poor prognosis in human lung adenocarcinoma.
The long noncoding RNA CAR intergenic 10 bound and stabilized transcription factor Y-box-binding protein 1 (YB-1), leading to up-regulation of the epidermal growth factor receptor (EGFR (显示 EGFR 抗体)) and proliferation of lung cancer cells.
Results firstly reported that YB-1 whose mRNA expression is regulated by HPV18 E6 promotes epithelial-mesenchymal transition and progression of cervical cancer via enhancing the expressions of Snail (显示 SNAI1 抗体).
YB-1 localization was significantly altered in the nuclei of tumor blasts derived from bone marrow or peripheral blood.
Two interacting partners of urokinase-type plasminogen activator (uPA) receptor (显示 PLAUR 抗体), the cysteine-rich angiogenic inducer 61 (Cyr61 (显示 CYR61 抗体)) and the Y-box-binding protein 1 (YB-1) were identified and their differential expression demonstrated in the triple-negative breast cancer (TNBC) cells as well as in tumors.
No other significant associations between clinical prognostic factors and YB-1/p18 (显示 CDKN2C 抗体) serum levels were detected.
The amounts of YB-1 and YB-1 mRNA in rabbit organs and several cell lines.
results prove direct inhibitory action of YB-1 on its mRNA translation, while the positive effect of PABP (显示 PABPC1 抗体) is realized through displacing YB-1 from the regulatory element
YB-1 is induced by Shh (显示 SHH 抗体) in CGNPs
this study shows that innate immunity activation by muramyl peptides is mediated via an interaction between YB1 and NOD2 (显示 NOD2 抗体)
In conclusion, TGF-beta (显示 TGFB1 抗体) signaling pathway may influence liver fibrosis by incorporating with YB-1, indicating that YB-1 could be a potential target for therapies against liver fibrosis.
Reduction in the expression of YBX1 and ILF3 controls the expression of pluripotency-related genes in ESCs (显示 NR2E3 抗体), suggesting their roles in further regulation of the pluripotent state of ESCs (显示 NR2E3 抗体).
In the initial stage of myocyte differentiation, transcription of the YB-1 gene was regulated by E2F1 (显示 E2F1 抗体) and Sp1 (显示 SP1 抗体), and was then gradually replaced under the control of both MyoD (显示 MYOD1 抗体) and myogenin (显示 MYOG 抗体).
YB-1 is a novel intracellular target of activated protein C (显示 PROC 抗体) in renal ischemia-reperfusion injury
miR (显示 MLXIP 抗体)-382 inhibits osteosarcoma metastasis and relapse by targeting YB-1 protein.
YB-1 was revealed in a population of Cajal bodies in 2-cell mouse embryos but not in other cells studied.
The effects of MIA/CD-RAP (显示 MIA 抗体) on transcriptional regulation in chondrocytes, through the regulation of p54(nrb (显示 NONO 抗体)) via YBX1 contributes to the understanding of chondrogenesis.
The formation of intracytoplasmic Gag-RNA complexes is facilitated by YB-1, which promotes MMTV virus assembly.
transcription factor; acts as a regulator of protein tyrosine phosphatase PTP1B expression
B box-binding protein
, CCAAT-binding transcription factor I subunit A
, DNA-binding protein B
, Y-box transcription factor
, Y-box-binding protein 1
, enhancer factor I subunit A
, major histocompatibility complex, class II, Y box-binding protein I
, nuclease sensitive element binding protein 1
, nuclease-sensitive element-binding protein 1
, CCAAT-binding transcription factor 1 subunit A
, DNA binding protein B
, Y box transcription factor
, enhancer factor 1 alpha
, enhancer factor 1 subunit A
, FRG Y
, frg y1
, frog Y-box proteins
, Y-box binding protein 1