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JMY 抗体

(Junction Mediating and Regulatory Protein, P53 Cofactor (JMY))
Acts both as a nuclear p53/TP53-cofactor and a cytoplasmic regulator of actin dynamics depending on conditions. In nucleus, acts as a cofactor that increases p53/TP53 response. Increases p53/TP53-dependent transcription and apoptosis, suggesting an important role in p53/TP53 stress response such as DNA damage. In cytoplasm, acts as a nucleation-promoting factor for both branched and unbranched actin filaments. Activates the Arp2/3 complex to induce branched actin filament networks. Also catalyzes actin polymerization in the absence of Arp2/3, creating unbranched filaments. Contributes to cell motility by controlling actin dynamics.
JMY 抗体  (AA 535-634) JMY 抗体  (AA 535-634) JMY 抗体 (AA 535-634) (ABIN530707)

JMY 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5B6 unconjugated

JMY 抗体  (AA 535-634) JMY 抗体  (AA 535-634) JMY 抗体 (AA 535-634) (ABIN530706)

JMY 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2D7 unconjugated

JMY 抗体  (AA 708-848) JMY 抗体  (AA 708-848) JMY 抗体 (AA 708-848) (ABIN7157162)

JMY 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

JMY 抗体 by 适用

Find JMY 抗体 for a variety of species such as anti-Human JMY, anti-Mouse JMY, anti-Cow JMY. The species listed below are among those available. Click on a link to go to the corresponding products.

JMY 抗体 by 应用范围

Find JMY 抗体 validated for a specific application such as WB, ELISA, IF, IHC. Some of the available applications are listed below. Click on a link to go to the corresponding products.

JMY 抗体 by 抗体来源

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JMY 抗体 by 抗原表位

Find JMY 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

JMY 抗体 by 克隆形成能力

Find available monoclonal or polyclonal JMY 抗体. Click on a link to go to the corresponding products.

JMY 抗体 by 克隆

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JMY 抗体 by 标记

Find JMY 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular JMY 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (4)
Cat. No. ABIN530707
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (3)
Cat. No. ABIN530706
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (2)
Cat. No. ABIN7157162
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN530705
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (5)
  • (1)
Cat. No. ABIN1881469
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF, ICC
Validations
  • (2)
Cat. No. ABIN6262708
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (1)
Cat. No. ABIN872348
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN7185068
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN3185267
Quantity 100 μL
Datasheet Datasheet
Reactivity Chicken, Cow, Dog, Human, Mouse, Pig
Application WB, IHC
Validations
  • (2)
Cat. No. ABIN7300900
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application
Validations
Cat. No. ABIN7157164
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7157165
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7157163
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application IHC (fp), IP
Validations
Cat. No. ABIN7454459
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
Cat. No. ABIN7452890
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our JMY 抗体

Coutts, Weston, La Thangue: "A transcription co-factor integrates cell adhesion and motility with the p53 response." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 47, pp. 19872-7, (2009) (PubMed).

Zuchero, Coutts, Quinlan, Thangue, Mullins: "p53-cofactor JMY is a multifunctional actin nucleation factor." in: Nature cell biology, Vol. 11, Issue 4, pp. 451-9, (2009) (PubMed).

Nordgard, Johansen, Alnaes, Bucher, Syvänen, Naume, Børresen-Dale, Kristensen: "Genome-wide analysis identifies 16q deletion associated with survival, molecular subtypes, mRNA expression, and germline haplotypes in breast cancer patients." in: Genes, chromosomes & cancer, Vol. 47, Issue 8, pp. 680-96, (2008) (PubMed).

Coutts, Boulahbel, Graham, La Thangue: "Mdm2 targets the p53 transcription cofactor JMY for degradation." in: EMBO reports, Vol. 8, Issue 1, pp. 84-90, (2007) (PubMed).

Shikama, Lee, France, Delavaine, Lyon, Krstic-Demonacos, La Thangue: "A novel cofactor for p300 that regulates the p53 response." in: Molecular cell, Vol. 4, Issue 3, pp. 365-76, (1999) (PubMed).

Aliases for JMY 抗体

junction mediating and regulatory protein, p53 cofactor (JMY) 抗体
junction mediating and regulatory protein, p53 cofactor (jmy) 抗体
junction-mediating and regulatory protein (Jmy) 抗体
WHDC1L3 抗体
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