RCC1 产品
(Regulator of Chromosome Condensation 1 (RCC1))
Categories
Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo- cytoplasmic transport, mitosis and nuclear-envelope assembly.
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Featured RCC1 Categories
Recommended RCC1 抗体
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ABIN6146817
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Cat. No.
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Recommended RCC1 ELISA试剂盒
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Recommended RCC1 蛋白
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Latest Publications for our RCC1 Products
: "C9orf72 arginine-rich dipeptide repeat proteins disrupt karyopherin-mediated nuclear import." in: eLife, Vol. 9, (2020) (PubMed).: "Exercise attenuates age-associated changes in motoneuron number, nucleocytoplasmic transport proteins and neuromuscular health." in: GeroScience, Vol. 40, Issue 2, pp. 177-192, (2018) (PubMed).
: "Structure-dependent mitochondrial dysfunction and hypoxia induced with single-walled carbon nanotubes." in: Small (Weinheim an der Bergstrasse, Germany), Vol. 10, Issue 14, pp. 2859-69, (2014) (PubMed).
: "Phosphorylation of RCC1 in mitosis is essential for producing a high RanGTP concentration on chromosomes and for spindle assembly in mammalian cells." in: Genes & development, Vol. 18, Issue 5, pp. 512-27, (2004) (PubMed).
: "Large-scale characterization of HeLa cell nuclear phosphoproteins." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 33, pp. 12130-5, (2004) (PubMed).
: "The dynamic association of RCC1 with chromatin is modulated by Ran-dependent nuclear transport." in: Molecular biology of the cell, Vol. 15, Issue 1, pp. 245-55, (2003) (PubMed).
: "Altered p27(Kip1) phosphorylation, localization, and function in human epithelial cells resistant to transforming growth factor beta-mediated G(1) arrest." in: Molecular and cellular biology, Vol. 22, Issue 9, pp. 2993-3002, (2002) (PubMed).
: "Perturbation of SUMOlation enzyme Ubc9 by distinct domain within nucleoporin RanBP2/Nup358." in: The Journal of biological chemistry, Vol. 277, Issue 7, pp. 4755-63, (2002) (PubMed).
: "Ran binds to chromatin by two distinct mechanisms." in: Current biology : CB, Vol. 12, Issue 13, pp. 1151-6, (2002) (PubMed).
: "Ran-binding protein 3 links Crm1 to the Ran guanine nucleotide exchange factor." in: The Journal of biological chemistry, Vol. 277, Issue 20, pp. 17385-8, (2002) (PubMed).
Synonyms and alternative names related to RCC1
regulator of chromosome condensation 1 (rcc1), regulator of chromosome condensation 1 (RCC1), regulator of chromosome condensation 1 L homeolog (rcc1.L), Regulator of chromosome condensation 1 (Rcc1), N terminal fragment of RCC1; similar to S. cerevisiae SRM1 (YGL097W) guanine nucleotide exchange factor for Gsp1 GTPase involved in assembly of nuclear pore complex; frameshifted (RCC1), regulator of chromosome condensation 1 S homeolog (rcc1.S), regulator of chromosome condensation 1 (Rcc1), 4931417M11Rik, AI326872, BJ1, CG10480, CG18640 (Bj1), Chc1, CHC1, chc1-a, chc1-b, Dmel\\CG10480, dRCC1, inxs, MGC115703, MGC132085, RanGEF, rcc1, RCC1, Rcc1, RCC1-I, sdt, SNHG3-RCC1, wu:fj77f08, xrcc1, zgc:65796, zgc:77114Protein level used designations for RCC1
- chromosome condensation 1
- fj77f08
- regulator of chromosome condensation
- regulator of chromosome condensation 1
- RCC1 protein
- Bj1-PA
- Bj1-PB
- Bj1-PC
- CG10480-PA
- CG10480-PB
- CG10480-PC
- in excess
- side-out
- possible fragment of potential guanine nucleotide exchange factor
- SNHG3-RCC1 readthrough transcript
- cell cycle regulatory protein
- guanine nucleotide-releasing protein
- chromosome condensation protein 1
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