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RCAN2 产品

(Regulator of Calcineurin 2 (RCAN2))

Categories

This gene encodes a member of the regulator of calcineurin (RCAN) protein family. These proteins play a role in many physiological processes by binding to the catalytic domain of calcineurin A, inhibiting calcineurin-mediated nuclear translocation of the transcription factor NFATC1. Expression of this gene in skin fibroblasts is upregulated by thyroid hormone, and the encoded protein may also play a role in endothelial cell function and angiogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011].

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Featured RCAN2 Categories

RCAN2 抗体

High quality antibodies with extensive validation data.

RCAN2 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended RCAN2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, FACS, IHC (p)
Validations
  • (1)
  • (4)
Cat. No. ABIN652191
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB, IHC, IF
Validations
  • (3)
Cat. No. ABIN7146282
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN523636
Quantity 50 μg
Datasheet Datasheet

Recommended RCAN2 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6207443
Quantity 96 tests
Datasheet Datasheet

Recommended RCAN2 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124811
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1317679
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3086907
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our RCAN2 Products

Qin, Pan, Wu, Bauman, Cardozo: "Anabolic steroids activate calcineurin-NFAT signaling and thereby increase myotube size and reduce denervation atrophy." in: Molecular and cellular endocrinology, Vol. 399, pp. 336-45, (2014) (PubMed).

Calicchio, Collins, Kozakewich: "Identification of signaling systems in proliferating and involuting phase infantile hemangiomas by genome-wide transcriptional profiling." in: The American journal of pathology, Vol. 174, Issue 5, pp. 1638-49, (2009) (PubMed).

Rothermel, Vega, Yang, Wu, Bassel-Duby, Williams: "A protein encoded within the Down syndrome critical region is enriched in striated muscles and inhibits calcineurin signaling." in: The Journal of biological chemistry, Vol. 275, Issue 12, pp. 8719-25, (2000) (PubMed).

Strippoli, Lenzi, Petrini, Carinci, Zannotti: "A new gene family including DSCR1 (Down Syndrome Candidate Region 1) and ZAKI-4: characterization from yeast to human and identification of DSCR1-like 2, a novel human member (DSCR1L2)." in: Genomics, Vol. 64, Issue 3, pp. 252-63, (2000) (PubMed).

Fuentes, Genescà, Kingsbury, Cunningham, Pérez-Riba, Estivill, de la Luna: "DSCR1, overexpressed in Down syndrome, is an inhibitor of calcineurin-mediated signaling pathways." in: Human molecular genetics, Vol. 9, Issue 11, pp. 1681-90, (2000) (PubMed).

Synonyms and alternative names related to RCAN2

regulator of calcineurin 2 (rcan2), regulator of calcineurin 2 (RCAN2), regulator of calcineurin 2 (Rcan2), CSP2, Csp2, Dcip2, DKFZp459H071, DSCR1L1, Dscr1l1, MCIP2, RCAN2, rcan2, RCN2, si:ch211-124g24.1, ZAKI-4, Zaki-4, ZAKI4, zgc:85746

Protein level used designations for RCAN2

  • regulator of calcineurin 2
  • calcipressin-2
  • Down syndrome critical region gene 1-like 1
  • Calcipressin-2
  • Down syndrome candidate region 1-like 1
  • myocyte-enriched calcineurin-interacting protein 2
  • thyroid hormone-responsive (skin fibroblasts)
  • thyroid hormone-responsive protein ZAKI-4
  • calcineurin inhibitory protein ZAKI-4
  • down syndrome candidate region 1-like protein 1
  • myocyte-enriched calcineurin interactin protein 2
  • Down syndrome critical region gene1-like 1
  • Down syndrome critical region gene 1-like 1 protein
  • down syndrome candidate region 1-like 1
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