RBP3 产品
(Retinol Binding Protein 3, Interstitial (RBP3))
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Interphotoreceptor retinol-binding protein is a large glycoprotein known to bind retinoids and found primarily in the interphotoreceptor matrix of the retina between the retinal pigment epithelium and the photoreceptor cells. It is thought to transport retinoids between the retinal pigment epithelium and the photoreceptors, a critical role in the visual process.The human IRBP gene is approximately 9.5 kbp in length and consists of four exons separated by three introns. The introns are 1.6-1.9 kbp long. The gene is transcribed by photoreceptor and retinoblastoma cells into an approximately 4.3-kilobase mRNA that is translated and processed into a glycosylated protein of 135,000 Da. The amino acid sequence of human IRBP can be divided into four contiguous homology domains with 33-38% identity, suggesting a series of gene duplication events. In the gene, the boundaries of these domains are not defined by exon-intron junctions, as might have been expected. The first three homology domains and part of the fourth are all encoded by the first large exon, which is 3,180 base pairs long. The remainder of the fourth domain is encoded in the last three exons, which are 191, 143, and approximately 740 base pairs long, respectively. [provided by RefSeq, Jul 2008].
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Featured RBP3 Categories
RBP3 抗体
High quality antibodies with extensive validation data.
RBP3 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
RBP3 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended RBP3 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Application
WB, IHC, IP, ICC
Validations
- (2)
Cat. No.
ABIN7444433
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
IHC
Validations
- (2)
Cat. No.
ABIN7233795
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
Cat. No.
ABIN519681
Quantity
50 μL
Datasheet
Datasheet
Recommended RBP3 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969936
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6962335
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959153
Quantity
96 tests
Datasheet
Datasheet
Recommended RBP3 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7124850
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1317651
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3094986
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our RBP3 Products
: "Recovery from experimental autoimmune uveitis promotes induction of antiuveitic inducible Tregs." in: Journal of leukocyte biology, Vol. 97, Issue 6, pp. 1101-9, (2015) (PubMed).: "Oral delivery of ACE2/Ang-(1-7) bioencapsulated in plant cells protects against experimental uveitis and autoimmune uveoretinitis." in: Molecular therapy : the journal of the American Society of Gene Therapy, Vol. 22, Issue 12, pp. 2069-82, (2014) (PubMed).
: "Both MC5r and A2Ar are required for protective regulatory immunity in the spleen of post-experimental autoimmune uveitis in mice." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 191, Issue 8, pp. 4103-11, (2013) (PubMed).
: "Following EAU recovery there is an associated MC5r-dependent APC induction of regulatory immunity in the spleen." in: Investigative ophthalmology & visual science, Vol. 52, Issue 12, pp. 8862-7, (2011) (PubMed).
: "Blk, a BH3-containing mouse protein that interacts with Bcl-2 and Bcl-xL, is a potent death agonist." in: The Journal of biological chemistry, Vol. 273, Issue 14, pp. 7783-6, (1998) (PubMed).
: "Functional dissection of the pro-apoptotic protein Bik. Heterodimerization with anti-apoptosis proteins is insufficient for induction of cell death." in: The Journal of biological chemistry, Vol. 272, Issue 39, pp. 24494-8, (1997) (PubMed).
: "Induction of apoptosis by human Nbk/Bik, a BH3-containing protein that interacts with E1B 19K." in: Molecular and cellular biology, Vol. 16, Issue 10, pp. 5857-64, (1996) (PubMed).
: "Bik, a novel death-inducing protein shares a distinct sequence motif with Bcl-2 family proteins and interacts with viral and cellular survival-promoting proteins." in: Oncogene, Vol. 11, Issue 9, pp. 1921-8, (1995) (PubMed).
Synonyms and alternative names related to RBP3
retinol binding protein 3 (rbp3), retinol binding protein 3 (RBP3), interphotoreceptor retinoid-binding protein (glr2547), interphotoreceptor retinoid-binding protein (XOO2681), interphotoreceptor retinoid-binding protein (AMED_0162), interphotoreceptor retinoid-binding protein (ambt_08395), retinol binding protein 3, interstitial (Rbp3), retinol binding protein 3 (Rbp3), D10S64, D10S65, D10S66, Irbp, IRBP, Rbp-3, RBPI, RP66Protein level used designations for RBP3
- irbp gene 2
- retinol-binding protein 3
- interphotoreceptor retinoid-binding protein
- retinol binding protein 3, interstitial
- retinol-binding protein 3-like
- interstitial retinol-binding protein
- interphotoreceptor retinoid binding protein
- interphotoreceptor retinol- binding protein
- 7S protein
- IRBP
- protein 7S
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