RAGE 蛋白
(Advanced Glycosylation End Product-Specific Receptor (AGER))
The advanced glycosylation end product (AGE) receptor encoded by this gene is a member of the immunoglobulin superfamily of cell surface receptors. It is a multiligand receptor, and besides AGE, interacts with other molecules implicated in homeostasis, development, and inflammation, and certain diseases, such as diabetes and Alzheimer's disease. Many alternatively spliced transcript variants encoding different isoforms, as well as non-protein-coding variants, have been described for this gene (PMID:18089847). [provided by RefSeq, May 2011].
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29 results
AGER
宿主: 人
宿主: HEK-293T Cells
Recombinant
WB, SDS, ELISA, PI
2 images
AGER
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
Greater than 95 % by SDS-PAGE gel analyses
WB, ELISA
1 image
AGER
宿主: 小鼠
宿主: HEK-293 Cells
Recombinant
> 96 % as determined by SDS-PAGE
Active
1 image
AGER
宿主: 人
宿主: HEK-293 Cells
Recombinant
The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
1 image
AGER
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
> 85 % as determined by reducing SDS-PAGE.
AGER
宿主: 大鼠
宿主: HEK-293 Cells
Recombinant
> 90 % as determined by reducing SDS-PAGE.
AGER
宿主: Cynomolgus
宿主: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE
AGER
宿主: 人
宿主: Mammalian Cells
Recombinant
>90 % as determined by SDS-PAGE.
WB, SDS, ELISA, Imm, AcA
Active
AGER
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 95 % as determined by reducing SDS-PAGE.
AGER
宿主: 小鼠
宿主: 大肠杆菌（E. Coli）
Recombinant
> 95 %
WB, SDS, Imm, PC
AGER
宿主: 大鼠
宿主: 大肠杆菌（E. Coli）
Recombinant
> 90 %
WB, SDS, Imm, PC
Latest Publications for our RAGE 蛋白
: "Nicousamide protects kidney podocyte by inhibiting the TGFβ receptor II phosphorylation and AGE-RAGE signaling." in: American journal of translational research, Vol. 9, Issue 1, pp. 115-125, (2017) (PubMed).: "PD-L1 (Programmed Death Ligand 1) Protects Against Experimental Intracerebral Hemorrhage-Induced Brain Injury." in: Stroke, Vol. 48, Issue 8, pp. 2255-2262, (2017) (PubMed).
: "A Novel, Multi-Target Natural Drug Candidate, Matrine, Improves Cognitive Deficits in Alzheimer's Disease Transgenic Mice by Inhibiting A? Aggregation and Blocking the RAGE/A? Axis." in: Molecular neurobiology, (2016) (PubMed).
: "The role of hyperglycemia in mechanisms of exacerbated inflammatory responses within the oral cavity." in: Cellular immunology, Vol. 272, Issue 1, pp. 45-52, (2011) (PubMed).
Aliases for RAGE 蛋白
advanced glycosylation end-product specific receptor (AGER) 蛋白advanced glycosylation end product-specific receptor (Ager) 蛋白
advanced glycosylation end-product specific receptor (Ager) 蛋白
MAPK/MAK/MRK overlapping kinase (LOC719012) 蛋白
AGER 蛋白
RAGE 蛋白
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