RAF1 蛋白
(V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1))
This gene is the cellular homolog of viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine/threonine specific protein kinases, ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration. Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| RAF1 Protein (AA 1-648) (GST tag) | 人 | 小麦胚 |
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| RAF1 Protein (AA 1-130) (GST tag) | 人 | 小麦胚 |
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| RAF1 Protein (His tag) | 人 | 大肠杆菌（E. Coli） |
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| RAF1 Protein (R391W) (GST tag) | 人 | Baculovirus infected Insect Cells |
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| RAF1 Protein (Y340E, Y341E) (GST tag) | 人 | Baculovirus infected Insect Cells |
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| RAF1 Protein (GST tag) | 人 | Baculovirus infected Insect Cells |
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| RAF1 Protein (AA 1-648) (Strep Tag) | 人 | Cell-free protein synthesis (CFPS) |
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| RAF1 Protein (AA 1-648) (Strep Tag) | 小鼠 | Cell-free protein synthesis (CFPS) |
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| RAF1 蛋白 | Hepatitis C Virus (HCV) | 大肠杆菌（E. Coli） |
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| RAF1 Protein (AA 2061-2302) (GST tag) | Hepatitis C Virus (HCV) | 大肠杆菌（E. Coli） |
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| RAF1 Protein (GST tag) | 人 | Insect Cells |
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| RAF1 Protein (AA 1-648, full length) (His-SUMO Tag) | 人 | 大肠杆菌（E. Coli） |
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| RAF1 Protein (Myc-DYKDDDDK Tag) | 人 | HEK-293 Cells |
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| RAF1 Protein (AA 1-648) (His tag) | 大鼠 | 酵母菌 |
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| RAF1 Protein (His tag) | Tick-Borne Encephalitis Virus (TBEV) | 大肠杆菌（E. Coli） |
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| RAF1 Protein (AA 342-619) (His tag) | 人 | Bacteria |
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| RAF1 Protein (His tag) | 人 | 大肠杆菌（E. Coli） |
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Protein
- AP (Affinity Purification: 所列应用)
- AA (Antibody Array: 所列应用)
- ELISA (ELISA: 所列应用)
- WB (Western Blotting: 所列应用)
1 reference - 宿主
- 人
- 宿主
- 小麦胚
- 蛋白类型
- Recombinant
Protein
- ELISA (ELISA: 所列应用)
- WB (Western Blotting: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
Protein
- KAA (Kinase Activity Assay: 所列应用)
- 宿主
- 人
- 宿主
- Baculovirus infected Insect Cells
- 蛋白类型
- Recombinant
- 生物活性
- Active
Protein
- WB (Western Blotting: 所列应用)
- KAA (Kinase Activity Assay: 所列应用)
- 宿主
- 人
- 宿主
- Baculovirus infected Insect Cells
- 蛋白类型
- Recombinant
- 生物活性
- Active
Protein
- 宿主
- 人
- 宿主
- Baculovirus infected Insect Cells
- 蛋白类型
- Recombinant
- 生物活性
- Active
Protein
- ELISA (ELISA: 所列应用)
- WB (Western Blotting: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- 质量等级
- custom-made
- 宿主
- 人
- 宿主
- Cell-free protein synthesis (CFPS)
- 蛋白类型
- Recombinant
- 纯度
- approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Protein
- ELISA (ELISA: 所列应用)
- WB (Western Blotting: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- 质量等级
- custom-made
- 宿主
- 小鼠
- 宿主
- Cell-free protein synthesis (CFPS)
- 蛋白类型
- Recombinant
- 纯度
- approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Protein
- ELISA (ELISA: 所列应用)
- WB (Western Blotting: 所列应用)
- 宿主
- Hepatitis C Virus (HCV)
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 95 % pure
Protein
- Func (Functional Studies: 所列应用)
- 宿主
- 人
- 宿主
- Insect Cells
- 蛋白类型
- Recombinant
- 纯度
- 70 % - 90 %
Protein
- SDS (SDS-PAGE: 有验证图片)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- Greater than 90 % as determined by SDS-PAGE.
Protein
- WB (Western Blotting: 有验证图片)
- AbP (Antibody Production: 所列应用)
- STD (Standard: 所列应用)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
Protein
- ELISA (ELISA: 所列应用)
- 宿主
- 大鼠
- 宿主
- 酵母菌
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
Protein
- ELISA (ELISA: 所列应用)
- WB (Western Blotting: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- Imm (Immunogen: 所列应用)
- 宿主
- Tick-Borne Encephalitis Virus (TBEV)
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
Protein
- ELISA (ELISA: 所列应用)
- WB (Western Blotting: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- Imm (Immunogen: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
Latest Publications for our RAF1 蛋白
: "NO-released zinc supports the simultaneous binding of Raf-1 and PKC? cysteine-rich domains to HINT1 protein at the mu-opioid receptor." in: Antioxidants & redox signaling, Vol. 14, Issue 12, pp. 2413-25, (2011) (PubMed).
Aliases for RAF1 蛋白
Raf-1 proto-oncogene, serine/threonine kinase (RAF1) 蛋白Raf-1 proto-oncogene, serine/threonine kinase (Raf1) 蛋白
Raf-1 proto-oncogene, serine/threonine kinase a (raf1a) 蛋白
Raf-1 proto-oncogene, serine/threonine kinase (raf1) 蛋白
v-raf-leukemia viral oncogene 1 (Raf1) 蛋白
Raf-1 proto-oncogene, serine/threonine kinase S homeolog (raf1.S) 蛋白
6430402F14Rik 蛋白
AA990557 蛋白
BB129353 蛋白
c-Raf 蛋白
c-raf 蛋白
CRAF 蛋白
craf 蛋白
cRaf 蛋白
Craf1 蛋白
D830050J10Rik 蛋白
NS5 蛋白
raf 蛋白
Raf-1 蛋白
raf1 蛋白
RAF1 蛋白
v-Raf 蛋白
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