(Protein tyrosine Phosphatase, Non-Receptor Type 9 (PTPN9))
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain that shares a significant similarity with yeast SEC14, which is a protein that has phosphatidylinositol transfer activity and is required for protein secretion through the Golgi complex in yeast. This PTP was found to be activated by polyphosphoinositide, and is thought to be involved in signaling events regulating phagocytosis. [provided by RefSeq, Jul 2008].
Kruger, Fukushima, Cherepanov, Borregaard, Loeve, Shek, Sharma, Tanswell, Chow, Downey: "Protein-tyrosine phosphatase MEG2 is expressed by human neutrophils. Localization to the phagosome and activation by polyphosphoinositides." in: The Journal of biological chemistry, Vol. 277, Issue 4, pp. 2620-8, (2002) (PubMed).
Qi, Zhao, Cao, Sui, Krantz, Zhao: "Purification and characterization of protein tyrosine phosphatase PTP-MEG2." in: Journal of cellular biochemistry, Vol. 86, Issue 1, pp. 79-89, (2002) (PubMed).
Aliases for PTPN9 抗体
protein tyrosine phosphatase, non-receptor type 9 (ptpn9) 抗体 protein tyrosine phosphatase, non-receptor type 9 (PTPN9) 抗体 protein tyrosine phosphatase, non-receptor type 9 (Ptpn9) 抗体 MEG2 抗体 Meg2 抗体 PTPMEG2 抗体