Phosphatase and Tensin Homolog 抗体
(Phosphatase and Tensin Homolog (PTEN))
This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded this gene is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT\\/PKB signaling pathway. [provided by RefSeq, Jul 2008].
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47 results :
PTEN
适用: 人
WB, IF, IHC (p)
宿主: 兔
Polyclonal
RB05082
unconjugated
2 references
PTEN
适用: 人
WB, IF, IHC (p)
宿主: 兔
Polyclonal
RB5083
unconjugated
1 reference
Latest Publications for our Phosphatase and Tensin Homolog 抗体
: "MiR221 promotes precursor B-cell retention in the bone marrow by amplifying the PI3K-signaling pathway in mice." in: European journal of immunology, Vol. 48, Issue 6, pp. 975-989, (2019) (PubMed).: "Gene expression profiles between cystic and solid vestibular schwannoma indicate susceptible molecules and pathways in the cystic formation of vestibular schwannoma." in: Functional & integrative genomics, Vol. 19, Issue 4, pp. 673-684, (2019) (PubMed).
: "TGF-β induces phosphorylation of phosphatase and tensin homolog: implications for fibrosis of the trabecular meshwork tissue in glaucoma." in: Scientific reports, Vol. 7, Issue 1, pp. 812, (2018) (PubMed).
: "Inhibitors of PARP-1 exert inhibitory effects on the biological characteristics of hepatocellular carcinoma cells in vitro." in: Molecular medicine reports, Vol. 16, Issue 1, pp. 208-214, (2018) (PubMed).
: "Pin1 Promotes Regulated Necrosis Induced by Glutamate in Rat Retinal Neurons via CAST/Calpain2 Pathway." in: Frontiers in cellular neuroscience, Vol. 11, pp. 425, (2018) (PubMed).
: "Bone marrow mesenchymal stem cell-derived exosomal miR-21 protects C-kit+ cardiac stem cells from oxidative injury through the PTEN/PI3K/Akt axis." in: PLoS ONE, Vol. 13, Issue 2, pp. e0191616, (2018) (PubMed).
: "Berberine inhibits IL-21/IL-21R mediated inflammatory proliferation of fibroblast-like synoviocytes through the attenuation of PI3K/Akt signaling pathway and ameliorates IL-21 mediated ..." in: Cytokine, Vol. 106, pp. 54-66, (2018) (PubMed).
: "Associations of Functional MicroRNA Binding Site Polymorphisms in IL23/Th17 Inflammatory Pathway Genes with Gastric Cancer Risk." in: Mediators of inflammation, Vol. 2017, pp. 6974696, (2018) (PubMed).
: "VprBP (DCAF1) Regulates RAG1 Expression Independently of Dicer by Mediating RAG1 Degradation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 201, Issue 3, pp. 930-939, (2018) (PubMed).
: "Changes in expression of special AT-rich sequence binding protein 1 and phosphatase and tensin homologue in kidneys of diabetic rats during ageing." in: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, Vol. 33, Issue 10, pp. 1734-1741, (2018) (PubMed).
Aliases for Phosphatase and Tensin Homolog 抗体
phosphatase and tensin homolog (PTEN) 抗体phosphatase and tensin homolog (Pten) 抗体
phosphatase and tensin homolog L homeolog (pten.L) 抗体
phosphatase and tensin homolog A (ptena) 抗体
phosphatase and tensin homolog B (ptenb) 抗体
10q23del 抗体
2310035O07Rik 抗体
A130070J02Rik 抗体
AI463227 抗体
B430203M17Rik 抗体
BZS 抗体
CWS1 抗体
DEC 抗体
fa11a08 抗体
fb73f10 抗体
fc83f12 抗体
fd16b10 抗体
fk90e11 抗体
GLM2 抗体
MHAM 抗体
Mmac 抗体
MMAC1 抗体
pten 抗体
PTEN1 抗体
PTENP1 抗体
si:bz1g13.4 抗体
TEP1 抗体
wu:fa11a08 抗体
wu:fb73f10 抗体
wu:fc52g04 抗体
wu:fc83f12 抗体
wu:fd16b10 抗体
wu:fk90e11 抗体
zgc:73086 抗体
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