PSMD2 产品
(Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 2 (PSMD2))
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The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits\; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid. In addition to participation in proteasome function, this subunit may also participate in the TNF signalling pathway since it interacts with the tumor necrosis factor type 1 receptor. A pseudogene has been identified on chromosome 1. [provided by RefSeq, Jul 2008].
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Featured PSMD2 Categories
PSMD2 抗体
High quality antibodies with extensive validation data.
PSMD2 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
PSMD2 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PSMD2 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (8)
Cat. No.
ABIN7439738
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Dog, Human, Monkey, Mouse, Rat
Application
WB, IF, IHC, IHC (p)
Validations
- (11)
Cat. No.
ABIN1500479
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (6)
Cat. No.
ABIN3015813
Quantity
100 μL
Datasheet
Datasheet
Recommended PSMD2 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN5648250
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Chicken
Analytical Method
Validations
Cat. No.
ABIN1773469
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Sheep
Analytical Method
Validations
Cat. No.
ABIN1774693
Quantity
96 tests
Datasheet
Datasheet
Recommended PSMD2 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1316633
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3094827
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3136721
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our PSMD2 Products
: "Acute ethanol exposure reduces serotonin receptor 1A internalization by increasing ubiquitination and degradation of β-arrestin2." in: The Journal of biological chemistry, Vol. 294, Issue 38, pp. 14068-14080, (2019) (PubMed).: "The transition zone protein Rpgrip1l regulates proteasomal activity at the primary cilium." in: The Journal of cell biology, Vol. 210, Issue 1, pp. 115-33, (2015) (PubMed).
: "Angiopoietin-2 secretion by endothelial cell exosomes: regulation by the phosphatidylinositol 3-kinase (PI3K)/Akt/endothelial nitric oxide synthase (eNOS) and syndecan-4/syntenin pathways." in: The Journal of biological chemistry, Vol. 289, Issue 1, pp. 510-9, (2014) (PubMed).
: "Impairment of proteostasis network in Down syndrome prior to the development of Alzheimer's disease neuropathology: redox proteomics analysis of human brain." in: Biochimica et biophysica acta, Vol. 1832, Issue 8, pp. 1249-59, (2013) (PubMed).
: "NAK is recruited to the TNFR1 complex in a TNFalpha-dependent manner and mediates the production of RANTES: identification of endogenous TNFR-interacting proteins by a proteomic approach." in: The Journal of biological chemistry, Vol. 279, Issue 51, pp. 53266-71, (2004) (PubMed).
Synonyms and alternative names related to PSMD2
26S proteasome non-ATPase regulatory subunit 2 (psmD2), 26S proteasome regulatory subunit S2 (NAEGRDRAFT_83014), 26S proteasome regulatory subunit S2 (DICPUDRAFT_55026), proteasome 26S subunit, non-ATPase 2 (psmd2), proteasome 26S subunit, non-ATPase 2 L homeolog (psmd2.L), proteasome 26S subunit, non-ATPase 2 S homeolog (psmd2.S), proteasome 26S subunit, non-ATPase 2 (PSMD2), proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 (psmd2), proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 (Psmd2), proteasome 26S subunit, non-ATPase 2 (Psmd2), 9430095H01Rik, AA407121, DDBDRAFT_0192101, DDBDRAFT_0232978, DDB_0192101, DDB_0232978, MGC83233, MGC97650, P97, psmd2, PSMD2, RPN1, S2, TEG-190, Tex190, TRAP2, zgc:65921Protein level used designations for PSMD2
- 26S proteasome regulatory subunit S2
- 26S proteasome non-ATPase regulatory subunit 2
- 26s proteasome regulatory subunit S2-like protein
- proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
- proteasome 26S non-ATPase subunit 2
- 55.11 protein
- TNFR-associated protein 2
- protein 55.11
- tumor necrosis factor type 1 receptor-associated protein 2
- 26S proteasome regulatory subunit RPN1
- 26S proteasome subunit p97
- testis expressed gene 190
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