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PSPH 产品

(Phosphoserine Phosphatase (PSPH))

Categories

The protein encoded by this gene belongs to a subfamily of the phosphotransferases. This encoded enzyme is responsible for the third and last step in L-serine formation. It catalyzes magnesium-dependent hydrolysis of L-phosphoserine and is also involved in an exchange reaction between L-serine and L-phosphoserine. Deficiency of this protein is thought to be linked to Williams syndrome. [provided by RefSeq, Jul 2008].

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Featured PSPH Categories

PSPH 抗体

High quality antibodies with extensive validation data.

PSPH ELISA试剂盒

Reliable ELISA kits for a wide range of species.

PSPH 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PSPH 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (4)
Cat. No. ABIN562501
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (4)
Cat. No. ABIN562500
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7163421
Quantity 100 μL
Datasheet Datasheet

Recommended PSPH ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5564548
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6951215
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6206856
Quantity 96 tests
Datasheet Datasheet

Recommended PSPH 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1316677
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1316675
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3128011
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our PSPH Products

Samanta, Park, Andrabi, Shelton, Gilkes, Semenza: "PHGDH Expression Is Required for Mitochondrial Redox Homeostasis, Breast Cancer Stem Cell Maintenance, and Lung Metastasis." in: Cancer research, Vol. 76, Issue 15, pp. 4430-42, (2016) (PubMed).

Possemato, Marks, Shaul, Pacold, Kim, Birsoy, Sethumadhavan, Woo, Jang, Jha, Chen, Barrett, Stransky, Tsun, Cowley, Barretina, Kalaany, Hsu, Ottina, Chan, Yuan, Garraway, Root, Mino-Kenudson et al.: "Functional genomics reveal that the serine synthesis pathway is essential in breast cancer. ..." in: Nature, Vol. 476, Issue 7360, pp. 346-50, (2011) (PubMed).

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Lamesch, Li, Milstein, Fan, Hao, Szabo, Hu, Venkatesan, Bethel, Martin, Rogers, Lawlor, McLaren, Dricot, Borick, Cusick, Vandenhaute, Dunham, Hill, Vidal: "hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes." in: Genomics, Vol. 89, Issue 3, pp. 307-15, (2007) (PubMed).

Veiga-da-Cunha, Collet, Prieur, Jaeken, Peeraer, Rabbijns, Van Schaftingen: "Mutations responsible for 3-phosphoserine phosphatase deficiency." in: European journal of human genetics : EJHG, Vol. 12, Issue 2, pp. 163-6, (2004) (PubMed).

Peeraer, Rabijns, Collet, Van Schaftingen, De Ranter: "How calcium inhibits the magnesium-dependent enzyme human phosphoserine phosphatase." in: European journal of biochemistry / FEBS, Vol. 271, Issue 16, pp. 3421-7, (2004) (PubMed).

Peeraer, Rabijns, Verboven, Collet, Van Schaftingen, De Ranter: "High-resolution structure of human phosphoserine phosphatase in open conformation." in: Acta crystallographica. Section D, Biological crystallography, Vol. 59, Issue Pt 6, pp. 971-7, (2003) (PubMed).

Kim, Heo, Kim, Park, Moon, Kim, Kwon, Yoon, Shin, Jeong, Park, Lee, Jeon, Ro, Cho, Hwang: "Molecular basis for the local conformational rearrangement of human phosphoserine phosphatase." in: The Journal of biological chemistry, Vol. 277, Issue 48, pp. 46651-8, (2002) (PubMed).

Veeranna, Shetty: "Phosphoserine phosphatase of human brain: partial purification, characterization, regional distribution, and effect of certain modulators including psychoactive drugs." in: Neurochemical research, Vol. 15, Issue 12, pp. 1203-10, (1991) (PubMed).

Synonyms and alternative names related to PSPH

phosphoserine phosphatase (PSPH), phosphoserine phosphatase (Psph), phosphoserine phosphatase L homeolog (psph.L), phosphoserine phosphatase (psph), phosphoserine phosphatase (serB), phosphoserine phosphatase (serB-1), PSP; O-phosphoserine phosphohydrolase; PSPase (serB), phosphoserine phosphatase (LOC5568588), phosphoserine phosphatase (PSP), phosphoserine phosphatase (Svir_29300), phosphoserine phosphatase SerB (MMAH_RS03435), BPI fold containing family A member 2 (BPIFA2), AI480570, DDBDRAFT_0183847, DDBDRAFT_0230054, DDB_0183847, DDB_0230054, MGC78828, PSP, PSPase, PSPH, psph, PSPHD, zgc:112414

Protein level used designations for PSPH

  • L-3-phosphoserine phosphatase
  • O-phosphoserine phosphohydrolase
  • PSPase
  • PSP
  • phosphoserine phosphatase
  • parotid secretory protein
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