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PSMF1 产品

(Proteasome (Prosome, Macropain) Inhibitor Subunit 1 (PI31) (PSMF1))

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The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits\; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a protein that inhibits the activation of the proteasome by the 11S and 19S regulators. Alternative transcript variants have been identified for this gene. [provided by RefSeq, Jul 2008].

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Featured PSMF1 Categories

PSMF1 抗体

High quality antibodies with extensive validation data.

PSMF1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PSMF1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF
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  • (5)
Cat. No. ABIN184933
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7164936
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (3)
Cat. No. ABIN1500490
Quantity 100 μL
Datasheet Datasheet

Recommended PSMF1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6229191
Quantity 96 tests
Datasheet Datasheet

Recommended PSMF1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124622
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3086589
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3124845
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our PSMF1 Products

Li, Thompson, Kumar, DeMartino: "Molecular and cellular roles of PI31 (PSMF1) protein in regulation of proteasome function." in: The Journal of biological chemistry, Vol. 289, Issue 25, pp. 17392-405, (2014) (PubMed).

Sadaka, Marloie-Provost, Soumelis, Benaroch: "Developmental regulation of MHC II expression and transport in human plasmacytoid-derived dendritic cells." in: Blood, Vol. 113, Issue 10, pp. 2127-35, (2009) (PubMed).

McCutchen-Maloney, Matsuda, Shimbara, Binns, Tanaka, Slaughter, DeMartino: "cDNA cloning, expression, and functional characterization of PI31, a proline-rich inhibitor of the proteasome." in: The Journal of biological chemistry, Vol. 275, Issue 24, pp. 18557-65, (2000) (PubMed).

Synonyms and alternative names related to PSMF1

proteasome inhibitor subunit 1 (PSMF1), proteasome inhibitor subunit 1 (Psmf1), proteasome (prosome, macropain) inhibitor subunit 1 (Psmf1), proteasome inhibitor subunit 1 (psmf1), AW048666, BC012260, PI31, zgc:92785

Protein level used designations for PSMF1

  • hPI31
  • proteasome inhibitor PI31 subunit
  • proteasome inhibitor hP131 subunit
  • proteasome inhibitor subunit 1
  • proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
  • proteasome (prosome, macropain) inhibitor subunit 1
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