PSMC4 产品
(Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 4 (PSMC4))
Categories
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits\; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the triple-A family of ATPases that is a component of the 19S regulatory subunit and plays a role in 26S proteasome assembly. The encoded protein interacts with gankyrin, a liver oncoprotein, and may also play a role in Parkinson's disease through interactions with synphilin-1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012].
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Featured PSMC4 Categories
Recommended PSMC4 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (8)
Cat. No.
ABIN7442066
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, IHC (p)
Validations
- (6)
Cat. No.
ABIN562488
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA
Validations
- (3)
Cat. No.
ABIN7142234
Quantity
100 μg
Datasheet
Datasheet
Recommended PSMC4 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1316605
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3119814
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7414021
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our PSMC4 Products
: "Chaperone-mediated 26S proteasome remodeling facilitates free K63 ubiquitin chain production and aggresome clearance." in: The Journal of biological chemistry, Vol. 290, Issue 15, pp. 9455-64, (2015) (PubMed).: "Genetic background alters the severity and onset of neuromuscular disease caused by the loss of ubiquitin-specific protease 14 (usp14)." in: PLoS ONE, Vol. 8, Issue 12, pp. e84042, (2013) (PubMed).
: "Differential expression of novel tyrosine kinase substrates during breast cancer development." in: Molecular & cellular proteomics : MCP, Vol. 6, Issue 12, pp. 2072-87, (2007) (PubMed).
Synonyms and alternative names related to PSMC4
26S protease regulatory subunit 6B (LOC732870), regulatory particle, ATPase-like-3 (rpt-3), 26S protease regulatory subunit 6B (ATEG_04674), 26S protease regulatory subunit 6B (LELG_01296), 26S protease regulatory subunit 6B (HCAG_00039), 26S proteasome regulatory subunit 6B (LOC5568998), 26S protease regulatory subunit 6B (GL50803_7950), 26S protease regulatory subunit 6B (EDI_044950), 26S protease regulatory subunit 6B (AOR_1_1218154), 26S protease regulatory subunit 6B (PTRG_03339), 26S protease regulatory subunit 6B (psmC4), 26S protease regulatory subunit 6B (prs6b), 26S protease regulatory subunit 6B (LOC100381342), proteasome 26S subunit, ATPase 4 (psmc4), proteasome 26S subunit, ATPase 4 (PSMC4), proteasome (prosome, macropain) 26S subunit, ATPase, 4 (Psmc4), proteasome 26S subunit, ATPase 4 (Psmc4), AO090003000692, CIP21, DDBDRAFT_0188209, DDBDRAFT_0191435, DDB_0188209, DDB_0191435, MIP224, NCU02260.1, RPT3, S6, TBP-7, TBP7, Tbp7Protein level used designations for PSMC4
- 26S protease regulatory subunit 6B
- 26S protease regulatory subunit 6b
- 26S proteasome subunit ATPase 4
- HIV TAT binding-protein-related
- 26S proteasome regulatory complex ATPase RPT3
- GRMZM2G090904
- 26S proteasome AAA-ATPase subunit RPT3
- MB67-interacting protein
- Tat-binding protein 7
- protease 26S subunit 6
- CAR interacing protein 21
- CAR interacting protein 21
- TAT-binding protein 7
- TBP-7
- proteasome 26S ATPase subunit 4
- proteasome 26S subunit ATPase 4
- S6 ATPase
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