CCL15 蛋白
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- 抗原 See all CCL15 蛋白
- CCL15 (Chemokine (C-C Motif) Ligand 15 (CCL15))
- 生物活性
- Active
- 宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 序列
- QFTNDAETEL MMSKLPLENP VVLNSFHFAA DCCTSYISQS IPCSLMKSYF ETSSECSKPG VIFLTKKGRQ VCAKPSGPGV QDCMKKLKPY S
- 产品特性
- Fully biologically active when compared to standard. The ED50 determined by a chemotaxis bioassay using human T-lymphocytes is less than 10 ng/ml, corresponding to a specific activity of >, 1.0 × 105 IU/mg.
- 纯度
- > 97 % by SDS-PAGE and HPLC analyses.
- 内毒素水平
- Level Less than 1EU/µg of rHuMIP-5/CCL15 as determined by LAL method
- Top Product
- Discover our top product CCL15 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20 °C. Further dilutions should be made in appropriate buffered solutions.
- 储存条件
- 4 °C
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- 抗原
- CCL15 (Chemokine (C-C Motif) Ligand 15 (CCL15))
- 别名
- MIP-5/CCL15 (CCL15 产品)
- 别名
- HCC-2 Protein, HMRP-2B Protein, LKN-1 Protein, LKN1 Protein, MIP-1 delta Protein, MIP-1D Protein, MIP-5 Protein, MRP-2B Protein, NCC-3 Protein, NCC3 Protein, SCYA15 Protein, SCYL3 Protein, SY15 Protein, C-C motif chemokine ligand 15 Protein, CCL15 Protein
- 背景
- CCL15, a new human CC chemokine, was isolated from a human fetal spleen cDNA library. CCL15 cDNA encodes a predicted 113 amino acid (aa) protein containing a putative signal peptide of 21 amino acids that is cleaved to generate a 92 aa residue mature protein. Within the CC family members, human CCL15 shares 45%, 44%, 35%, and 30% aa homology with mouse C10, human MPIF-1, human HCC-1, and mouse MIP-1γ, respectively. The gene for MIP-5 is found on chromosome 17 where the genes for most of the human CC chemokines are located. Human CCL15 is expressed in T and B lymphocytes, NK cells, monocytes and monocyte-derived dendritic cells. Human MIP-5 is chemotactic for T cells and monocytes and has been shown to induce calcium flux in human CCR-1-transfected cells. Synonym: MIP-5/CCL15, Human. Formulation: Lyophilized from a 0.2µm filtered concentrated solution in 20mM PB, pH 7.4, 100mM NaCl.
- 分子量
- 10.1 kDa, a single non-glycosylated polypeptide chain containing 92 amino acids.
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