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CXCL2 蛋白

CXCL2 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) > 97 % by SDS-PAGE and HPLC analyses. Active
产品编号 ABIN988160
发货至: 中国
  • 抗原 See all CXCL2 蛋白
    CXCL2 (Chemokine (C-X-C Motif) Ligand 2 (CXCL2))
    生物活性
    Active
    宿主
    • 16
    • 9
    • 6
    • 2
    • 1
    • 1
    小鼠
    资源
    • 22
    • 3
    • 2
    • 2
    • 2
    • 1
    大肠杆菌(E. Coli)
    序列
    AVVASELRCQ CLKTLPRVDF KNIQSLSVTP PGPHCAQTEV IATLKGGQKV CLDPEAPLVQ KIIQKILNKG KA
    产品特性
    Fully biologically active when compared to standard. The ED50 determined by a chemotaxis bioassay using human neutrophils is less than 10 ng/ml, corresponding to a specific activity of >, 1.0 × 105 IU/mg.
    纯度
    > 97 % by SDS-PAGE and HPLC analyses.
    内毒素水平
    Level Less than 1EU/µg of rMuMIP-2/CXCL2 as determined by LAL method
    Top Product
    Discover our top product CXCL2 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20 °C. Further dilutions should be made in appropriate buffered solutions.
    储存条件
    4 °C
  • 抗原
    CXCL2 (Chemokine (C-X-C Motif) Ligand 2 (CXCL2))
    别名
    MIP-2/CXCL2 (CXCL2 产品)
    别名
    CINC-2a Protein, GRO2 Protein, GROb Protein, MGSA-b Protein, MIP-2a Protein, MIP2 Protein, MIP2A Protein, SCYB2 Protein, GRO3 Protein, Gro2 Protein, MIP-2 Protein, Mgsa-b Protein, Mip2 Protein, Scyb Protein, Scyb2 Protein, Mip-2 Protein, GROB Protein, MIP-2alpha Protein, C-X-C motif chemokine ligand 2 Protein, chemokine (C-X-C motif) ligand 2 Protein, CXCL2 Protein, Cxcl2 Protein
    背景
    Macrophage Inflammatory Protein 2 (MIP-2) was originally identified as a heparin binding protein secreted from a mouse macrophage cell line in response to endotoxin stimulation. Based on its protein and DNA sequences, MIP-2 is a member of the alpha (CXC) subfamily of chemokines.Similarly to other alpha chemokines, mouse MIP-2 is a potent neutrophil attractant and activator. MIP-2 and KC can bind the mouse interleukin 8 type B receptor homologue with high affinity. The expression of MIP-2 was found to be associated with neutrophil influx in pulmonary inflammation and glomerulonephritis, suggesting that MIP-2 may contribute to the pathogenesis of inflammatory diseases. Synonym: MIP-2/CXCL2, Mouse. Formulation: Lyophilized from a 0.2µm filtered concentrated solution in 20mM PB, pH 7.4, 150mM NaCl.
    分子量
    7.8 kDa, a single, non-glycosylated polypeptide chain containing 73 amino acids.
    途径
    Cellular Response to Molecule of Bacterial Origin
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