beta Defensin 1 蛋白
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- 抗原 See all beta Defensin 1 (DEFB1) 蛋白
- beta Defensin 1 (DEFB1) (Defensin, beta 1 (DEFB1))
- 生物活性
- Active
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 序列
- GNFLTGLGHR SDHYNCVSSG GQCLYSACPI FTKIQGTCYR GKAKCC
- 产品特性
- Fully biologically active when compared to standard. The ED50 determined by a chemotaxis bioassay usingCD34+ dendritic cells is less than 1000 ng/ml, corresponding to a specific activity of >, 1.0 × 103 IU/mg.
- 纯度
- > 98 % by SDS-PAGE and HPLC analyses.
- 内毒素水平
- Level Less than 1EU/µg of rHuBD-1 as determined by LAL method
- Top Product
- Discover our top product DEFB1 蛋白
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Defensin, beta 1 (DEFB1) (Active) protein
DEFB1 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Defensin, beta 1 (DEFB1) (Active) proteinDEFB1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Defensin, beta 1 (DEFB1) (AA 22-68) protein (His tag)DEFB1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Defensin, beta 1 (DEFB1) (AA 33-69) protein (His tag)DEFB1 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Defensin, beta 1 (DEFB1) (AA 1-68) protein (GST tag)DEFB1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20 °C. Further dilutions should be made in appropriate buffered solutions.
- 储存条件
- 4 °C
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- 抗原
- beta Defensin 1 (DEFB1) (Defensin, beta 1 (DEFB1))
- 别名
- beta-Defensin 1 (BD-1) (DEFB1 产品)
- 别名
- BD1 Protein, DEFB-1 Protein, DEFB101 Protein, HBD1 Protein, AW260221 Protein, BD-1 Protein, DEFB1-like Protein, RHBD-1 Protein, CBD1 Protein, PBD-1 Protein, DEFB1 Protein, BNBD-1 Protein, defensin beta 1 Protein, avian beta-defensin 1 Protein, defensin, beta 1 Protein, beta-defensin 1-like Protein, beta-defensin 1 Protein, DEFB1 Protein, Defb1 Protein, AvBD1 Protein, LOC100861170 Protein
- 背景
- Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The ª-defensins are distinguished from the beta-defensins by the pairing of their three disulfide bonds. To date, four human beta-defensins have been identified, BD-1, BD-2, BD-3 and BD-4. beta-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they are chemoattractant towards immature dendritic cells and memory T cells. The beta-defensin proteins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a signal sequence and, in the case of BD-1 (36 a.a.), a propeptide region. beta-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. beta-Defensins are 3-5 kDa peptides ranging in size from 33-47 amino acid residues. Synonym: beta-Defensin 1 (BD-1), Human. Formulation: Lyophilized from a 0.2µm filtered concentrated solution in 20mM PB, pH 7.4, 130mM NaCl.
- 分子量
- Approximately 5.0 KDa, a single non-glycosylated polypeptide chain containing 47 amino acids.
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