WISP3 蛋白
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北京 101111
Quick Overview for WISP3 蛋白 (ABIN935912)
抗原
See all WISP3 蛋白蛋白类型
生物活性
宿主
资源
纯度
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序列
- TGPLDTTPEG RPGEVSDAPQ RKQFCHWPCK CPQQKPRCPP GVSLVRDGCG CCKICAKQPG EICNEADLCD PHKGLYCDYS VDRPRYETGV CAYLVAVGCE FNQVHYHNGQ VFQPNPLFSC LCVSGAIGCT PLFIPKLAGS HCSGAKGGKK SDQSNCSLEP LLQQLSTSYK TMPAYRNLPL IWKKKCLVQA TKWTPCSRTC GMGISNRVTN ENSNCEMRKE KRLCYIQPCD SNILKTIKIP KGKTCQPTFQ LSKAEKFVFS GCSSTQSYKP TFCGICLDKR CCIPNKSKMI TIQFDCPNEG SFKWKMLWIT SCVCQRNCRE PGDIFSELKI L
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产品特性
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Purified recombinant Human WISP3 protein
Expression System: E.coli
Bioactivity: The ED50 was determined by the dose-dependant proliferation of the MCF-7 cell line. The expected ED50 for this effect is 0.2-0.3 µg/mL. -
内毒素水平
- < 0.1 ng per µg (1 EU/µg).
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstitute in 10 M Acetic Acid o a concentration of 0.1 - 1.0 mg/mL.
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缓冲液
- Supplied lyophilized from 10 mM CH3COOH.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- WISP3 (Wnt1 Inducible Signaling Pathway Protein 3 (WISP3))
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别名
- WISP3
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背景
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WISP-3 is a member of the CCN family of secreted cysteine rich regulatory proteins. It is predominantly expressed in the adult kidney, testis and fetal kidney and weaker expression in placenta, ovary, prostate, small intestine, and skeletally-derived cells. WISP-3 is required for normal postnatal skeletal growth and cartilage homeostasis. Human WISP-3 is a 36.8 kDa protein containing 331 amino acid residues. It is composed of four distinct structural domains (modules), the IGF binding protein (IGFBP) domain, the von Willebrand Factor C (VWFC) domain, the thrombospondin type-1 repeat (TSP type-1) domain, and a C-terminal cystine knot-like (CTCK) domain.
Alternative Names: CCN6 protein, WISP 3 protein, WISP-3, WISP-3 protein, WNT-1 inducible signaling pathway protein-3 protein, WISP-3 protein, WISP 3, WISP3 -
途径
- WNT signaling, Growth Factor Binding
抗原
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